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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 106176262.

SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans

Valerie J. Robert, Matthieu Caron, Loic Gely, Annie Adrait, Victoria Pakulska, Yohann Couté, Manon Chevalier, Christian G. Riedel, Cecile Bedet, Francesca Palladino

Development. 2023 Nov 1; 150(21): dev201755. Published online 2023 Oct 17. doi: 10.1242/dev.201755

PMCID:: PMC10617626

Abstract Article

Select item 100942973.

The Attenuation of Insulin/IGF-1 Signaling Pathway Plays a Crucial Role in the Myo-Inositol-Alleviated Aging in Caenorhabditis elegans

Nae-Cherng Yang, Chia-Yu Chin, Ya-Xin Zheng, Inn Lee

Int J Mol Sci. 2023 Apr; 24(7): 6194. Published online 2023 Mar 24. doi: 10.3390/ijms24076194

PMCID:: PMC10094297

Abstract Article PDF–3.1M

Select item 97487234.

Characterizing Variants of Unknown Significance of the PTEN tumour suppressorHomolog DAF-18

Glafira Ermakova, Chadwick Hou, Jeffrey Boudreau, William G Bendena, Ian D Chin-Sang

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000689. Published online 2022 Nov 28. doi: 10.17912/micropub.biology.000689

PMCID:: PMC9748723

Abstract Article PDF–2.3M

Select item 93713565.

The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan

İçten Meraş, Laëtitia Chotard, Thomas Liontis, Zakaria Ratemi, Benjamin Wiles, Jung Hwa Seo, Jeremy M. Van Raamsdonk, Christian E. Rocheleau

PLoS Genet. 2022 Aug; 18(8): e1010328. Published online 2022 Aug 1. doi: 10.1371/journal.pgen.1010328

PMCID:: PMC9371356

Abstract Article PDF–3.3M

Select item 91571516.

Genetic analysis of DAF-18/PTEN missense mutants for the ability to maintain quiescence of the somatic gonad and germ line in Caenorhabditis elegans dauer larvae

Julia Wittes, Iva Greenwald

G3 (Bethesda) 2022 Jun; 12(6): jkac093. Published online 2022 Apr 22. doi: 10.1093/g3journal/jkac093

PMCID:: PMC9157151

Abstract Article PDF–1.0M

Select item 91571427.

Genetic analysis of daf-18/PTEN missense mutants for starvation resistance and developmental regulation during Caenorhabditis elegans L1 arrest

Jingxian Chen, Linda Y Tang, Maya E Powell, James M Jordan, L Ryan Baugh

G3 (Bethesda) 2022 Jun; 12(6): jkac092. Published online 2022 Apr 22. doi: 10.1093/g3journal/jkac092

PMCID:: PMC9157142

Abstract Article PDF–1.6M

Select item 90106578.

Pediococcus acidilactici Promotes the Longevity of C. elegans by Regulating the Insulin/IGF-1 and JNK/MAPK Signaling, Fat Accumulation and Chloride Ion

Rui Hu, Yong Zhang, Weiyi Qian, Yan Leng, Yan Long, Xinjie Liu, Jinping Li, Xiangyuan Wan, Xun Wei

Front Nutr. 2022; 9: 821685. Published online 2022 Apr 1. doi: 10.3389/fnut.2022.821685

PMCID:: PMC9010657

Abstract Article PDF–1.6M

Select item 87334579.

Insulin signaling and osmotic stress response regulate arousal and developmental progression of C. elegans at hatching

Emily A Bayer, Katarina M Liberatore, Jordan R Schneider, Evan Schlesinger, Zhengying He, Susanna Birnbaum, Bruce Wightman

Genetics. 2022 Jan; 220(1): iyab202. Published online 2021 Nov 12. doi: 10.1093/genetics/iyab202

PMCID:: PMC8733457

Abstract Article PDF–1.1M

Select item 849270710.

C. elegans feed yolk to their young in a form of primitive lactation

Carina C. Kern, StJohn Townsend, Antoine Salzmann, Nigel B. Rendell, Graham W. Taylor, Ruxandra M. Comisel, Lazaros C. Foukas, Jürg Bähler, David Gems

Nat Commun. 2021; 12: 5801. Published online 2021 Oct 5. doi: 10.1038/s41467-021-25821-y

PMCID:: PMC8492707

Abstract Article PDF–1.5M

Select item 846353911.

A PTEN variant uncouples longevity from impaired fitness in Caenorhabditis elegans with reduced insulin/IGF-1 signaling

Hae-Eun H. Park, Wooseon Hwang, Seokjin Ham, Eunah Kim, Ozlem Altintas, Sangsoon Park, Heehwa G. Son, Yujin Lee, Dongyeop Lee, Won Do Heo, Seung-Jae V. Lee

Nat Commun. 2021; 12: 5631. Published online 2021 Sep 24. doi: 10.1038/s41467-021-25920-w

PMCID:: PMC8463539

Abstract Article PDF–4.1M

Select item 833118312.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 829448713.

DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence

Amanda L. Fry, Amy K. Webster, Julia Burnett, Rojin Chitrakar, L. Ryan Baugh, E. Jane Albert Hubbard

PLoS Genet. 2021 Jul; 17(7): e1009650. Published online 2021 Jul 21. doi: 10.1371/journal.pgen.1009650

PMCID:: PMC8294487

Abstract Article PDF–3.0M

Select item 800114914.

Caffeic and Dihydrocaffeic Acids Promote Longevity and Increase Stress Resistance in Caenorhabditis elegans by Modulating Expression of Stress-Related Genes

Sofia M. Gutierrez-Zetina, Susana González-Manzano, Begoña Ayuda-Durán, Celestino Santos-Buelga, Ana M. González-Paramás

Molecules. 2021 Mar; 26(6): 1517. Published online 2021 Mar 10. doi: 10.3390/molecules26061517

PMCID:: PMC8001149

Abstract Article PDF–1.6M

Select item 799517615.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 754981516.

Mutually exclusive dendritic arbors in C. elegans neurons share a common architecture and convergent molecular cues

Rebecca J. Androwski, Nadeem Asad, Janet G. Wood, Allison Hofer, Steven Locke, Cassandra M. Smith, Becky Rose, Nathan E. Schroeder

PLoS Genet. 2020 Sep; 16(9): e1009029. Published online 2020 Sep 30. doi: 10.1371/journal.pgen.1009029

PMCID:: PMC7549815

Abstract Article PDF–3.7M

Select item 747914517.

The precursor of PI(3,4,5)P₃ alleviates aging by activating daf-18(Pten) and independent of daf-16

Dawei Shi, Xian Xia, Aoyuan Cui, Zhongxiang Xiong, Yizhen Yan, Jing Luo, Guoyu Chen, Yingying Zeng, Donghong Cai, Lei Hou, Joseph McDermott, Yu Li, Hong Zhang, Jing-Dong J. Han

Nat Commun. 2020; 11: 4496. Published online 2020 Sep 8. doi: 10.1038/s41467-020-18280-4

PMCID:: PMC7479145

Abstract Article PDF–2.0M

Select item 725232018.

Effects of ASD-associated daf-18/PTEN missense variants on C. elegans dauer development

Carolina González-Cavazos, Mengyi Cao, Wan-Rong Wong, Cynthia Chai, Paul W Sternberg

MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000177. Published online 2019 Oct 16. doi: 10.17912/micropub.biology.000177

PMCID:: PMC7252320

Article PDF–334K

Select item 697187819.

WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans

Basten L Snoek, Mark G Sterken, Margi Hartanto, Albert-Jan van Zuilichem, Jan E Kammenga, Dick de Ridder, Harm Nijveen

Database (Oxford) 2020; 2020: baz149. Published online 2020 Jan 21. doi: 10.1093/database/baz149

PMCID:: PMC6971878

Abstract Article PDF–1.0M

Select item 694365320.

Exploring Target Genes Involved in the Effect of Quercetin on the Response to Oxidative Stress in Caenorhabditis elegans

Begoña Ayuda-Durán, Susana González-Manzano, Antonio Miranda-Vizuete, Eva Sánchez-Hernández, Marta R. Romero, Montserrat Dueñas, Celestino Santos-Buelga, Ana M. González-Paramás

Antioxidants (Basel) 2019 Dec; 8(12): 585. Published online 2019 Nov 25. doi: 10.3390/antiox8120585