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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 103450902.

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi

Nat Commun. 2023; 14: 4176. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39882-8

PMCID:: PMC10345090

Abstract Article PDF–8.1M

Select item 103356763.

Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

Zhongliang Hu, Yamei Luo, Yuting Liu, Yaru Luo, Liangce Wang, Shengsong Gou, Yuling Peng, Rui Wei, Da Jia, Yuan Wang, Shangbang Gao, Yan Zhang

PLoS Biol. 2023 Jul; 21(7): e3002165. Published online 2023 Jul 11. doi: 10.1371/journal.pbio.3002165

PMCID:: PMC10335676

Abstract Article PDF–2.2M

Select item 102273754.

Mechanistic impacts of bacterial diet on dopaminergic neurodegeneration in a Caenorhabditis elegans α-synuclein model of Parkinson’s disease

Anthony L. Gaeta, Karolina Willicott, Corey W. Willicott, Luke E. McKay, Candice M. Keogh, Tyler J. Altman, Logan C. Kimble, Abigail L. Yarbrough, Kim A. Caldwell, Guy A. Caldwell

iScience. 2023 Jun 16; 26(6): 106859. Published online 2023 May 12. doi: 10.1016/j.isci.2023.106859

PMCID:: PMC10227375

Abstract Article PDF–3.6M

Select item 101329775.

Ageing-associated changes in transcriptional elongation influence longevity

Cédric Debès, Antonios Papadakis, Sebastian Grönke, Özlem Karalay, Luke S. Tain, Athanasia Mizi, Shuhei Nakamura, Oliver Hahn, Carina Weigelt, Natasa Josipovic, Anne Zirkel, Isabell Brusius, Konstantinos Sofiadis, Mantha Lamprousi, Yu-Xuan Lu, Wenming Huang, Reza Esmaillie, Torsten Kubacki, Martin R. Späth, Bernhard Schermer, Thomas Benzing, Roman-Ulrich Müller, Adam Antebi, Linda Partridge, Argyris Papantonis, Andreas Beyer

Nature. 2023; 616(7958): 814–821. Published online 2023 Apr 12. doi: 10.1038/s41586-023-05922-y

PMCID:: PMC10132977

Abstract Article PDF–12M

Select item 101053286.

Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness

Ellen Geens, Pieter Van de Walle, Francesca Caroti, Rob Jelier, Christian Steuwe, Liliane Schoofs, Liesbet Temmerman

Life Sci Alliance. 2023 Jun; 6(6): e202201675. Published online 2023 Apr 14. doi: 10.26508/lsa.202201675

PMCID:: PMC10105328

Abstract Article PDF–2.0M

Select item 96083537.

Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrest

Amy K. Webster, Rojin Chitrakar, Seth M. Taylor, L. Ryan Baugh

Cell Rep. Author manuscript; available in PMC 2022 Oct 27.

Published in final edited form as: Cell Rep. 2022 Oct 11; 41(2): 111473. doi: 10.1016/j.celrep.2022.111473

PMCID:: PMC9608353

Abstract Article PDF–2.7M

Select item 95791518.

The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans

Mehul Vora, Stephanie M. Pyonteck, Tatiana Popovitchenko, Tarmie L. Matlack, Aparna Prashar, Nanci S. Kane, John Favate, Premal Shah, Christopher Rongo

Nat Commun. 2022; 13: 6168. Published online 2022 Oct 18. doi: 10.1038/s41467-022-33849-x

PMCID:: PMC9579151

Abstract Article PDF–2.9M

Select item 94327179.

Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans

Anthony L. Gaeta, J. Brucker Nourse, Jr., Karolina Willicott, Luke E. McKay, Candice M. Keogh, Kylie Peter, Shannon N. Russell, Shusei Hamamichi, Laura A. Berkowitz, Kim A. Caldwell, Guy A. Caldwell

PLoS Genet. 2022 Aug; 18(8): e1010115. Published online 2022 Aug 19. doi: 10.1371/journal.pgen.1010115

PMCID:: PMC9432717

Abstract Article PDF–2.7M

Select item 924683510.

C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens

Shouyong Ju, Hanqiao Chen, Shaoying Wang, Jian Lin, Yanli Ma, Raffi V. Aroian, Donghai Peng, Ming Sun

Commun Biol. 2022; 5: 643. Published online 2022 Jun 30. doi: 10.1038/s42003-022-03589-1

PMCID:: PMC9246835

Abstract Article PDF–5.1M

Select item 916964611.

The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans

Diego M. Jofré, Dane K. Hoffman, Ailen S. Cervino, Gabriella M. Hahn, McKenzie Grundy, Sijung Yun, Francis R. G. Amrit, Donna B. Stolz, Luciana F. Godoy, Esteban Salvatore, Fabiana A. Rossi, Arjumand Ghazi, M. Cecilia Cirio, Judith L. Yanowitz, Daniel Hochbaum

Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2109508119. Published online 2022 Apr 8. doi: 10.1073/pnas.2109508119

PMCID:: PMC9169646

Abstract Article PDF–2.0M

Select item 907367312.

Inducible degradation of dosage compensation protein DPY-27 facilitates isolation of Caenorhabditis elegans males for molecular and biochemical analyses

Qianyan Li, Arshdeep Kaur, Benjamin Mallory, Sara Hariri, JoAnne Engebrecht

G3 (Bethesda) 2022 May; 12(5): jkac085. Published online 2022 Apr 11. doi: 10.1093/g3journal/jkac085

PMCID:: PMC9073673

Abstract Article PDF–1.5M

Select item 833118313.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517614.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 794118115.

Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop

Yujin Lee, Yoonji Jung, Dae-Eun Jeong, Wooseon Hwang, Seokjin Ham, Hae-Eun H. Park, Sujeong Kwon, Jasmine M. Ashraf, Coleen T. Murphy, Seung-Jae V. Lee

J Cell Biol. 2021 May 3; 220(5): e202006174. Published online 2021 Mar 5. doi: 10.1083/jcb.202006174

PMCID:: PMC7941181

Abstract Article PDF–4.4M

Select item 788875116.

Caenorhabditis elegans establishes germline versus soma by balancing inherited histone methylation

Brandon S. Carpenter, Teresa W. Lee, Caroline F. Plott, Juan D. Rodriguez, Jovan S. Brockett, Dexter A. Myrick, David J. Katz

Development. 2021 Feb 1; 148(3): dev196600. Published online 2021 Feb 10. doi: 10.1242/dev.196600

PMCID:: PMC7888751

Abstract Article

Select item 772545517.

RNA polymerase II CTD S2P is dispensable for embryogenesis but mediates exit from developmental diapause in C. elegans

C. Cassart, C. Yague-Sanz, F. Bauer, P. Ponsard, F. X. Stubbe, V. Migeot, M. Wery, A. Morillon, F. Palladino, V. Robert, D. Hermand

Sci Adv. 2020 Dec; 6(50): eabc1450. Published online 2020 Dec 9. doi: 10.1126/sciadv.abc1450

PMCID:: PMC7725455

Abstract Article PDF–3.9M

Select item 761325818.

Gene expression profiling of epidermal cell types in C. elegans using Targeted DamID

Dimitris Katsanos, Mar Ferrando-Marco, Iqrah Razzaq, Gabriel Aughey, Tony D. Southall, Michalis Barkoulas

Development. 2021 Sep 1; 148(17): dev199452. Published online 2021 Sep 3. doi: 10.1242/dev.199452

PMCID:: PMC7613258

Abstract Article

Select item 726531119.

Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Yasmine J. Liu, Rebecca L. McIntyre, Georges E. Janssens, Evan G. Williams, Jiayi Lan, Michel van Weeghel, Bauke Schomakers, Henk van der Veen, Nicole N. van der Wel, Pallas Yao, William B. Mair, Ruedi Aebersold, Alyson W. MacInnes, Riekelt H. Houtkooper

J Cell Biol. 2020 Jun 1; 219(6): e201907067. Published online 2020 Apr 7. doi: 10.1083/jcb.201907067

PMCID:: PMC7265311

Abstract Article PDF–7.5M

Select item 688528920.

Mitochondrial Oxidative Stress Impairs Energy Metabolism and Reduces Stress Resistance and Longevity of C. elegans

Benjamin Dilberger, Stefan Baumanns, Fabian Schmitt, Tommy Schmiedl, Martin Hardt, Uwe Wenzel, Gunter P. Eckert

Oxid Med Cell Longev. 2019; 2019: 6840540. Published online 2019 Nov 15. doi: 10.1155/2019/6840540

PMCID:: PMC6885289

Abstract Article PDF–1.1M

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