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Select item 105538191.

ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia

Ananya Mahapatra, Alfa Dhakal, Aika Noguchi, Pranathi Vadlamani, Heather A. Hundley

PLoS Biol. 2023 Sep; 21(9): e3002150. Published online 2023 Sep 25. doi: 10.1371/journal.pbio.3002150

PMCID:: PMC10553819

Abstract Article PDF–1.7M

Select item 104418032.

Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways

Yi-Ting Tsai, Chen-Hsi Chang, Hsin-Yue Tsai

PLoS Genet. 2023 Aug; 19(8): e1010869. Published online 2023 Aug 9. doi: 10.1371/journal.pgen.1010869

PMCID:: PMC10441803

Abstract Article PDF–3.9M

Select item 104151813.

An intestinal sphingolipid confers intergenerational neuroprotection

Wenyue Wang, Tessa Sherry, Xinran Cheng, Qi Fan, Rebecca Cornell, Jie Liu, Zhicheng Xiao, Roger Pocock

Nat Cell Biol. 2023; 25(8): 1196–1207. Published online 2023 Aug 3. doi: 10.1038/s41556-023-01195-9

PMCID:: PMC10415181

Abstract Article PDF–4.4M

Select item 103450904.

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi

Nat Commun. 2023; 14: 4176. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39882-8

PMCID:: PMC10345090

Abstract Article PDF–8.1M

Select item 102877385.

Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

Eunah Kim, Andrea Annibal, Yujin Lee, Hae-Eun H. Park, Seokjin Ham, Dae-Eun Jeong, Younghun Kim, Sangsoon Park, Sujeong Kwon, Yoonji Jung, JiSoo Park, Sieun S. Kim, Adam Antebi, Seung-Jae V. Lee

Nat Commun. 2023; 14: 3716. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39393-6

PMCID:: PMC10287738

Abstract Article PDF–1.7M

Select item 99528816.

Selective Destabilization of Transcripts by mRNA Decapping Regulates Oocyte Maturation and Innate Immunity Gene Expression during Ageing in C. elegans

Fivos Borbolis, Dimitra Ranti, Maria-Despina Papadopoulou, Sofia Dimopoulou, Apostolos Malatras, Ioannis Michalopoulos, Popi Syntichaki

Biology (Basel) 2023 Feb; 12(2): 171. Published online 2023 Jan 21. doi: 10.3390/biology12020171

PMCID:: PMC9952881

Abstract Article PDF–4.1M

Select item 99104037.

Early-life starvation alters lipid metabolism in adults to cause developmental pathology in Caenorhabditis elegans

James M Jordan, Amy K Webster, Jingxian Chen, Rojin Chitrakar, L Ryan Baugh

Genetics. 2023 Feb; 223(2): iyac172. Published online 2022 Nov 30. doi: 10.1093/genetics/iyac172

PMCID:: PMC9910403

Abstract Article PDF–6.6M

Select item 98566748.

Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments

İrem Çelen, Aroshan Jayasinghe, Jung H. Doh, Chandran R. Sabanayagam

Cells. 2023 Jan; 12(2): 270. Published online 2023 Jan 10. doi: 10.3390/cells12020270

PMCID:: PMC9856674

Abstract Article PDF–2.2M

Select item 98086179.

Systematic transcriptome analysis associated with physiological and chronological aging in Caenorhabditis elegans

Seokjin Ham, Sieun S. Kim, Sangsoon Park, Eun Ji E. Kim, Sujeong Kwon, Hae-Eun H. Park, Yoonji Jung, Seung-Jae V. Lee

Genome Res. 2022 Nov-Dec; 32(11-12): 2003–2014. doi: 10.1101/gr.276515.121

PMCID:: PMC9808617

Abstract Article PDF–2.2M

Select item 957915110.

The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans

Mehul Vora, Stephanie M. Pyonteck, Tatiana Popovitchenko, Tarmie L. Matlack, Aparna Prashar, Nanci S. Kane, John Favate, Premal Shah, Christopher Rongo

Nat Commun. 2022; 13: 6168. Published online 2022 Oct 18. doi: 10.1038/s41467-022-33849-x

PMCID:: PMC9579151

Abstract Article PDF–2.9M

Select item 951484911.

H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

Meng Huang, Minjie Hong, Xinhao Hou, Chengming Zhu, Di Chen, Xiangyang Chen, Shouhong Guang, Xuezhu Feng

eLife. 2022; 11: e74812. Published online 2022 Sep 20. doi: 10.7554/eLife.74812

PMCID:: PMC9514849

Abstract Article PDF–2.1M

Select item 946503612.

Gonadotropin-releasing hormone-like receptor 2 inversely regulates somatic proteostasis and reproduction in Caenorhabditis elegans

Mor Kishner, Libat Habaz, Lana Meshnik, Tomer Dvir Meidan, Alexandra Polonsky, Anat Ben-Zvi

Front Cell Dev Biol. 2022; 10: 951199. Published online 2022 Aug 29. doi: 10.3389/fcell.2022.951199

PMCID:: PMC9465036

Abstract Article PDF–1.9M

Select item 939137913.

Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons

Tina Pekec, Jarosław Lewandowski, Alicja A. Komur, Daria Sobańska, Yanwu Guo, Karolina Świtońska-Kurkowska, Jędrzej M. Małecki, Abhishek Anil Dubey, Wojciech Pokrzywa, Marcin Frankowski, Maciej Figiel, Rafal Ciosk

Nat Commun. 2022; 13: 4883. Published online 2022 Aug 19. doi: 10.1038/s41467-022-32500-z

PMCID:: PMC9391379

Abstract Article PDF–2.5M

Select item 912776914.

Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions

Alejandra Zárate-Potes, Irtiqa Ali, Margarida Ribeiro Camacho, Hayley Brownless, Alexandre Benedetto

Front Microbiol. 2022; 13: 853629. Published online 2022 May 10. doi: 10.3389/fmicb.2022.853629

PMCID:: PMC9127769

Abstract Article PDF–4.6M

Select item 875312215.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663