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Select item 109663871.

The tyrosine kinase inhibitor Gefitinib reduces C. elegans stress-induced sleep, but not likely via LET-23/EGFR inhibition

Caroline Coto, Adrian Arimie, Jesse G Jones, Cheryl Van Buskirk

MicroPubl Biol. 2024; 2024: 10.17912/micropub.biology.001138. Published online 2024 Mar 12. doi: 10.17912/micropub.biology.001138

PMCID:: PMC10966387

Abstract Article PDF–758K

Select item 106922752.

Golgi localization of the LIN-2/7/10 complex points to a role in basolateral secretion of LET-23 EGFR in the Caenorhabditis elegans vulval precursor cells

Kimberley D. Gauthier, Christian E. Rocheleau

Development. 2021 Mar 1; 148(5): dev194167. Published online 2021 Mar 5. doi: 10.1242/dev.194167

PMCID:: PMC10692275

Abstract Article

Select item 97934183.

EGFR signal transduction is downregulated in C. elegans vulval precursor cells during dauer diapause

Catherine O'Keeffe, Iva Greenwald

Development. 2022 Nov 1; 149(21): dev201094. Published online 2022 Oct 31. doi: 10.1242/dev.201094

PMCID:: PMC9793418

Abstract Article

Select item 95260674.

Discovery of nonautonomous modulators of activated Ras

Marcos Corchado-Sonera, Komal Rambani, Kristen Navarro, Raleigh Kladney, James Dowdle, Gustavo Leone, Helen M Chamberlin

G3 (Bethesda) 2022 Oct; 12(10): jkac200. Published online 2022 Aug 5. doi: 10.1093/g3journal/jkac200

PMCID:: PMC9526067

Abstract Article PDF–1.2M

Select item 94737485.

SALSA, a genetically-encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo

Justin M. Shaffer, Iva Greenwald

Dev Cell. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Dev Cell. 2022 Apr 11; 57(7): 930–944.e6. doi: 10.1016/j.devcel.2022.03.008

PMCID:: PMC9473748

Abstract Article PDF–2.3M

Select item 87830446.

Reciprocal EGFR signaling in the anchor cell ensures precise inter-organ connection during Caenorhabditis elegans vulval morphogenesis

Silvan Spiri, Simon Berger, Louisa Mereu, Andrew DeMello, Alex Hajnal

Development. 2022 Jan 1; 149(1): dev199900. Published online 2022 Jan 4. doi: 10.1242/dev.199900

PMCID:: PMC8783044

Abstract Article

Select item 85534287.

Overactive EGF signaling suppresses a C. eleganspnc-1 egg-laying phenotype independent of known signaling mediators.

Matt Crook, Wendy Hanna-Rose

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000482. Published online 2021 Oct 4. doi: 10.17912/micropub.biology.000482

PMCID:: PMC8553428

Abstract Article PDF–2.1M

Select item 81085138.

LIN-10 can promote LET-23 EGFR signaling and trafficking independently of LIN-2 and LIN-7

Kimberley D. Gauthier, Christian E. Rocheleau

Mol Biol Cell. 2021 Apr 15; 32(8): 788–799. doi: 10.1091/mbc.E20-07-0490

PMCID:: PMC8108513

Abstract Article PDF–3.9M

Select item 80806629.

A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics

Jessica Knox, Nicolas Joly, Edmond M. Linossi, José A. Carmona-Negrón, Natalia Jura, Lionel Pintard, William Zuercher, Peter J. Roy

Sci Rep. 2021; 11: 9161. Published online 2021 Apr 28. doi: 10.1038/s41598-021-88150-6

PMCID:: PMC8080662

Abstract Article PDF–4.3M

Select item 747701410.

Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum

Marialetizia Motta, Luca Pannone, Francesca Pantaleoni, Gianfranco Bocchinfuso, Francesca Clementina Radio, Serena Cecchetti, Andrea Ciolfi, Martina Di Rocco, Mariet W. Elting, Eva H. Brilstra, Stefania Boni, Laura Mazzanti, Federica Tamburrino, Larry Walsh, Katelyn Payne, Alberto Fernández-Jaén, Mythily Ganapathi, Wendy K. Chung, Dorothy K. Grange, Ashita Dave-Wala, Shalini C. Reshmi, Dennis W. Bartholomew, Danielle Mouhlas, Giovanna Carpentieri, Alessandro Bruselles, Simone Pizzi, Emanuele Bellacchio, Francesca Piceci-Sparascio, Christina Lißewski, Julia Brinkmann, Ronald R. Waclaw, Quinten Waisfisz, Koen van Gassen, Ingrid M. Wentzensen, Michelle M. Morrow, Sara Álvarez, Mónica Martínez-García, Alessandro De Luca, Luigi Memo, Giuseppe Zampino, Cesare Rossi, Marco Seri, Bruce D. Gelb, Martin Zenker, Bruno Dallapiccola, Lorenzo Stella, Carlos E. Prada, Simone Martinelli, Elisabetta Flex, Marco Tartaglia

Am J Hum Genet. 2020 Sep 3; 107(3): 499–513. Published online 2020 Jul 27. doi: 10.1016/j.ajhg.2020.06.018

PMCID:: PMC7477014

Abstract Article PDF–3.6M

Select item 735158611.

Overactive EGF signaling promotes uv1 cell survival via increased phosphatidylcholine levels and suppression of SBP-1

Matt Crook, Wendy Hanna-Rose

MicroPubl Biol. 2020; 2020: 10.17912/micropub.biology.000266. Published online 2020 Jun 29. doi: 10.17912/micropub.biology.000266

PMCID:: PMC7351586

Article PDF–2.8M

Select item 725227212.

EOR-1 and EOR-2 act independently of RAS and WNT signaling pathways in RMED/V neuron specification

Xun Huang, Yishi Jin

MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000140. Published online 2019 Jul 31. doi: 10.17912/micropub.biology.000140

PMCID:: PMC7252272

Article PDF–1.0M

Select item 711515913.

Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males

Jimmy Goncalves, Yufeng Wan, Xiaoyan Guo, Kyoungsun Rha, Brigitte LeBoeuf, Liusuo Zhang, Kerolayne Estler, L. René Garcia

iScience. 2020 Apr 24; 23(4): 100990. Published online 2020 Mar 19. doi: 10.1016/j.isci.2020.100990

PMCID:: PMC7115159

Abstract Article PDF–8.6M

Select item 705796114.

A quiescent state following mild sensory arousal in Caenorhabditis elegans is potentiated by stress

Patrick D. McClanahan, Jessica M. Dubuque, Daphne Kontogiorgos-Heintz, Ben F. Habermeyer, Joyce H. Xu, Anthony M. Ma, David M. Raizen, Christopher Fang-Yen

Sci Rep. 2020; 10: 4140. Published online 2020 Mar 5. doi: 10.1038/s41598-020-60994-4