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Select item 107457011.

Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer

Mehdi Chaib, Jeremiah R. Holt, Emilie L. Fisher, Laura M. Sipe, Margaret S. Bohm, Sydney C. Joseph, Boston W. Simmons, Samson Eugin Simon, Johnathan R. Yarbro, Ubaid Tanveer, Jessica L. Halle, James A. Carson, T.J. Hollingsworth, QingQing Wei, Jeffrey C. Rathmell, Paul G. Thomas, D. Neil Hayes, Liza Makowski

Sci Adv. 2023 Dec 22; 9(51): eadd3231. Published online 2023 Dec 22. doi: 10.1126/sciadv.add3231

PMCID:: PMC10745701

Abstract Article PDF–2.0M

Select item 105142402.

MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel

Ping Lu, Yonghui Zhao, Zili Xie, Huan Zhou, Xinzhong Dong, Gregory F. Wu, Brian S. Kim, Jing Feng, Hongzhen Hu

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Apr 25; 42(4): 112283. Published online 2023 Mar 22. doi: 10.1016/j.celrep.2023.112283

PMCID:: PMC10514240

Abstract Article PDF–2.0M

Select item 103769343.

Dual Regulation of Spine-Specific and Synapse-to-Nucleus Signaling by PKCδ during Plasticity

Lesley A. Colgan, Paula Parra-Bueno, Heather L. Holman, Xun Tu, Anant Jain, Mariah F. Calubag, Jaime A. Misler, Chancellor Gary, Goksu Oz, Irena Suponitsky-Kroyter, Elwy Okaz, Ryohei Yasuda

J Neurosci. 2023 Jul 26; 43(30): 5432–5447. doi: 10.1523/JNEUROSCI.0208-22.2023

PMCID:: PMC10376934

Abstract Article PDF–1.9M

Select item 96601894.

The metabolomics of a protein kinase C delta (PKCδ) knock-out mouse model

Du Toit Loots, Adetomiwa Ayodele Adeniji, Mari Van Reenen, Mumin Ozturk, Frank Brombacher, Suraj P. Parihar

Metabolomics. 2022; 18(11): 92. Published online 2022 Nov 13. doi: 10.1007/s11306-022-01949-w

PMCID:: PMC9660189

Abstract Article PDF–2.6M

Select item 94819335.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 91708086.

Inhibition of PKC‐δ reduce rhabdomyolysis‐induced acute kidney injury

Dengke Wu, Jian Pan, Dongshan Zhang

J Cell Mol Med. 2022 Jun; 26(11): 3243–3253. Published online 2022 May 2. doi: 10.1111/jcmm.17331

PMCID:: PMC9170808

Abstract Article PDF–4.1M

Select item 89995227.

Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells

Norikiyo Honzawa, Kei Fujimoto, Masaki Kobayashi, Daisuke Kohno, Osamu Kikuchi, Hiromi Yokota-Hashimoto, Eri Wada, Yuichi Ikeuchi, Yoko Tabei, Gerald W. Dorn, II, Kazunori Utsunomiya, Rimei Nishimura, Tadahiro Kitamura

Int J Mol Sci. 2022 Apr; 23(7): 4003. Published online 2022 Apr 4. doi: 10.3390/ijms23074003

PMCID:: PMC8999522

Abstract Article PDF–10M

Select item 87673148.

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs

Shao-bin Wang, Siddharth Narendran, Shuichiro Hirahara, Akhil Varshney, Felipe Pereira, Ivana Apicella, Meenakshi Ambati, Vidya L. Ambati, Praveen Yerramothu, Kameshwari Ambati, Yosuke Nagasaka, Dionne Argyle, Peirong Huang, Kirstie L. Baker, Kenneth M. Marion, Kartik Gupta, Bo Liu, David R. Hinton, Scott W. Canna, Tamer Sallam, Srinivas R. Sadda, Nagaraj Kerur, Bradley D. Gelfand, Jayakrishna Ambati

Sci Immunol. Author manuscript; available in PMC 2022 Jun 3.

Published in final edited form as: Sci Immunol. 2021 Dec 3; 6(66): eabi4493. Published online 2021 Dec 3. doi: 10.1126/sciimmunol.abi4493

PMCID:: PMC8767314

Abstract Article PDF–1.0M

Select item 86104929.

Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria

Saori Fukao, Kei Haniuda, Hiromasa Tamaki, Daisuke Kitamura

eLife. 2021; 10: e72116. Published online 2021 Oct 25. doi: 10.7554/eLife.72116

PMCID:: PMC8610492

Abstract Article PDF–1.4M

Select item 848173810.

Endothelial deletion of PKCδ prevents VEGF inhibition and restores blood flow reperfusion in diabetic ischemic limb

Laura Croteau, Clément Mercier, Étienne Fafard-Couture, Alexandre Nadeau, Stéphanie Robillard, Valérie Breton, Andréanne Guay, Farah Lizotte, Marc-Antoine Despatis, Pedro Geraldes

Diab Vasc Dis Res. 2021 Mar-Apr; 18(2): 1479164121999033. Published online 2021 Mar 15. doi: 10.1177/1479164121999033

PMCID:: PMC8481738

Abstract Article PDF–3.9M

Select item 844895211.

Protein kinase C δ as a neuronal mechanism for headache in a chronic intermittent nitroglycerin model of migraine in mice

Ying He, Zuoxiao Shi, Yavnika Kashyap, Robert O. Messing, Zaijie Jim Wang

Pain. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Pain. 2021 Oct 1; 162(10): 2499–2511. doi: 10.1097/j.pain.0000000000002353

PMCID:: PMC8448952

Article PDF–3.9M

Select item 832113212.

TREM-1 inhibition attenuates neuroinflammation via PKC δ/CARD9 signaling pathway after intracerebral hemorrhage in mice

Qin Lu, Rui Liu, Prativa Sherchan, Reng Ren, Wei He, Yuanjian Fang, Yi Huang, Hui Shi, Lihui Tang, Shuxu Yang, John H. Zhang, Jiping Tang

Stroke. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Stroke. 2021 Jun; 52(6): 2162–2173. Published online 2021 May 5. doi: 10.1161/STROKEAHA.120.032736

PMCID:: PMC8321132

Abstract Article PDF–1.5M

Select item 824872813.

PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice

Yuko S. Niino, Ikuo Kawashima, Yoshinobu Iguchi, Hiroaki Kanda, Kiyoshi Ogura, Kaoru Mita-Yoshida, Tomio Ono, Maya Yamazaki, Kenji Sakimura, Satomi Yogosawa, Kiyotsugu Yoshida, Seiji Shioda, Takaya Gotoh

PLoS One. 2021; 16(7): e0253912. Published online 2021 Jul 1. doi: 10.1371/journal.pone.0253912

PMCID:: PMC8248728

Abstract Article PDF–4.0M

Select item 816404614.

Phosphorylation of protein kinase Cδ Tyr311 positively regulates thromboxane generation in platelets

John C. Kostyak, Benjamin Mauri, Akruti Patel, Carol Dangelmaier, Haritha Reddy, Satya P. Kunapuli

J Biol Chem. 2021 Jan-Jun; 296: 100720. Published online 2021 Apr 28. doi: 10.1016/j.jbc.2021.100720

PMCID:: PMC8164046

Abstract Article PDF–1.3M

Select item 795191915.

MARK2 phosphorylates eIF2α in response to proteotoxic stress

Yu-Ning Lu, Sarah Kavianpour, Tao Zhang, Xumei Zhang, Dao Nguyen, Ravi Thombre, Lu He, Jiou Wang

PLoS Biol. 2021 Mar; 19(3): e3001096. Published online 2021 Mar 11. doi: 10.1371/journal.pbio.3001096

PMCID:: PMC7951919

Abstract Article PDF–3.7M

Select item 793877016.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 777121717.

Disruption of Astrocytic Glutamine Turnover by Manganese Is Mediated by the Protein Kinase C Pathway

MARTA SIDORYK-WEGRZYNOWICZ, EUNSOOK LEE, NI MINGWEI, MICHAEL ASCHNER

Glia. Author manuscript; available in PMC 2020 Dec 29.

Published in final edited form as: Glia. 2011 Nov; 59(11): 1732–1743. Published online 2011 Aug 2. doi: 10.1002/glia.21219

PMCID:: PMC7771217

Abstract Article PDF–1.0M

Select item 749489718.

PKC-δ deficiency in B cells displays osteopenia accompanied with upregulation of RANKL expression and osteoclast–osteoblast uncoupling

Shangfu Li, Qiuli Liu, Depeng Wu, Tianwei He, Jinbo Yuan, Heng Qiu, Jennifer Tickner, Song Guo Zheng, Xiaojuan Li, Jiake Xu, Limin Rong

Cell Death Dis. 2020 Sep; 11(9): 762. Published online 2020 Sep 16. doi: 10.1038/s41419-020-02947-3

PMCID:: PMC7494897

Abstract Article PDF–13M

Select item 746473019.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s Disease

Manikandan Samidurai, Prashant Tarale, Chelva Janarthanam, Crystal Gomez Estrada, Richard Gordon, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy

Cells. 2020 Aug; 9(8): 1831. Published online 2020 Aug 4. doi: 10.3390/cells9081831

PMCID:: PMC7464730

Abstract Article PDF–6.7M

Select item 741599120.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

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