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Items: 1 to 20 of 60

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Discovery and validation of genes driving drug‐intake and related behavioral traits in mice
Tyler A. Roy, Jason A. Bubier, Price E. Dickson, Troy D. Wilcox, Juliet Ndukum, James W. Clark, Stacey J. Sukoff Rizzo, John C. Crabbe, James M. Denegre, Karen L. Svenson, Robert E. Braun, Vivek Kumar, Stephen A. Murray, Jacqueline K. White, Vivek M. Philip, Elissa J. Chesler
Genes Brain Behav. 2024 Feb; 23(1): e12875. Published online 2024 Jan 2. doi: 10.1111/gbb.12875
PMCID:
PMC10780947
AbstractArticlePDF–2.6M
3.
Low ceruloplasmin levels exacerbate retinal degeneration in a hereditary hemochromatosis model
Brandon D. Anderson, Timothy Lee, Brent Bell, Ying Song, Joshua L. Dunaief
Dis Model Mech. 2023 Jul 1; 16(7): dmm050226. Published online 2023 Jul 13. doi: 10.1242/dmm.050226
PMCID:
PMC10354715
AbstractArticle
4.
Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis
Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner
Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6
PMCID:
PMC10335937
AbstractArticlePDF–25M
5.
Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
Liping Xie, Yanmei Yuan, Simiao Xu, Sijia Lu, Jinyang Gu, Yanping Wang, Yibing Wang, Xianjing Zhang, Suzhen Chen, Jian Li, Junxi Lu, Honglin Sun, Ruixiang Hu, Hailong Piao, Wen Wang, Cunchuan Wang, Jing Wang, Na Li, Morris F. White, Liu Han, Weiping Jia, Ji Miao, Junli Liu
Cell Rep. Author manuscript; available in PMC 2023 May 2.
Published in final edited form as: Cell Rep. 2022 Oct 18; 41(3): 111498. doi: 10.1016/j.celrep.2022.111498
PMCID:
PMC10153649
AbstractArticlePDF–1.6M
6.
Ceruloplasmin-Deficient Mice Show Dysregulation of Lipid Metabolism in Liver and Adipose Tissue Reduced by a Protein Replacement
Sara Raia, Antonio Conti, Alan Zanardi, Barbara Ferrini, Giulia Maria Scotti, Enrica Gilberti, Giuseppe De Palma, Samuel David, Massimo Alessio
Int J Mol Sci. 2023 Jan; 24(2): 1150. Published online 2023 Jan 6. doi: 10.3390/ijms24021150
PMCID:
PMC9863737
AbstractArticlePDF–3.9M
7.
The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice
Zhong-Da Li, Haiyan Li, Shaomeng Kang, Yan-Ge Cui, Huiwen Zheng, Peina Wang, Kang Han, Peng Yu, Yan-Zhong Chang
Cell Death Dis. 2022 Nov; 13(11): 1006. Published online 2022 Nov 28. doi: 10.1038/s41419-022-05459-4
PMCID:
PMC9705310
AbstractArticlePDF–11M
8.
Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration
Yingrui Liu, Bailey Baumann, Ying Song, Kevin Zhang, Jacob K. Sterling, Samira Lakhal-Littleton, Zbynek Kozmik, Guanfang Su, Joshua L. Dunaief
Exp Eye Res. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Exp Eye Res. 2022 May; 218: 108988. Published online 2022 Feb 21. doi: 10.1016/j.exer.2022.108988
PMCID:
PMC9050912
AbstractArticlePDF–808K
9.
Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis
Kevin R. Zhang, Bailey Baumann, Ying Song, Jacob Sterling, Elizabeth A. Erler, Samyuktha Guttha, Zbynek Kozmik, Joshua L. Dunaief
Exp Eye Res. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Exp Eye Res. 2022 May; 218: 109028. Published online 2022 Mar 8. doi: 10.1016/j.exer.2022.109028
PMCID:
PMC9050911
AbstractArticlePDF–2.0M
10.
Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems
D.A. Santiago González, V.T. Cheli, S.L. Rosenblum, G. Denaroso, P.M. Paez
Redox Biol. 2021 Oct; 46: 102118. Published online 2021 Aug 27. doi: 10.1016/j.redox.2021.102118
PMCID:
PMC8408659
AbstractArticlePDF–31M
11.
Schwann Cells Provide Iron to Axonal Mitochondria and Its Role in Nerve Regeneration
Bruno Siqueira Mietto, Priya Jhelum, Katrin Schulz, Samuel David
J Neurosci. 2021 Aug 25; 41(34): 7300–7313. doi: 10.1523/JNEUROSCI.0900-21.2021
PMCID:
PMC8387113
AbstractArticlePDF–3.2M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Klf14 is an imprinted transcription factor that regulates placental growth
Erik Koppes, Ben Shaffer, Elena Sadovsky, Katherine Himes, Yaacov Barak, Yoel Sadovsky, J. Richard Chaillet
Placenta. Author manuscript; available in PMC 2020 Dec 31.
Published in final edited form as: Placenta. 2019 Dec; 88: 61–67. Published online 2019 Sep 27. doi: 10.1016/j.placenta.2019.09.013
PMCID:
PMC7774094
AbstractArticlePDF–834K
14.
Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling
Krishnakali Dasgupta, Jong Uk Chung, Kesava Asam, Juhee Jeong
Dev Biol. Author manuscript; available in PMC 2020 Nov 15.
Published in final edited form as: Dev Biol. 2019 Nov 15; 455(2): 434–448. Published online 2019 Jul 24. doi: 10.1016/j.ydbio.2019.07.015
PMCID:
PMC6842427
AbstractArticlePDF–6.1M
15.
Ceruloplasmin Regulates Iron Levels in the CNS and Prevents Free Radical Injury
Bharatkumar N. Patel, Robert J. Dunn, Suh Young Jeong, Qinzhang Zhu, Jean-Pierre Julien, Samuel David
J Neurosci. 2002 Aug 1; 22(15): 6578–6586. doi: 10.1523/JNEUROSCI.22-15-06578.2002
PMCID:
PMC6758125
AbstractArticlePDF–830K
16.
Age-Related Changes in Iron Homeostasis and Cell Death in the Cerebellum of Ceruloplasmin-Deficient Mice
Suh Young Jeong, Samuel David
J Neurosci. 2006 Sep 20; 26(38): 9810–9819. doi: 10.1523/JNEUROSCI.2922-06.2006
PMCID:
PMC6674433
AbstractArticlePDF–589K
17.
Ceruloplasmin Protects Injured Spinal Cord from Iron-Mediated Oxidative Damage
Khizr I. Rathore, Bradley J. Kerr, Adriana Redensek, Rubèn López-Vales, Suh Young Jeong, Prem Ponka, Samuel David
J Neurosci. 2008 Nov 26; 28(48): 12736–12747. doi: 10.1523/JNEUROSCI.3649-08.2008
PMCID:
PMC6671786
AbstractArticlePDF–742K
18.
Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes
Zheng Chen, Ruiwei Jiang, Mengxia Chen, Jiashuo Zheng, Min Chen, Nady Braidy, Shunli Liu, Guohao Liu, Zaitunamu Maimaitiming, Tianqi Shen, Joshua L. Dunaief, Christopher D. Vulpe, Gregory J. Anderson, Huijun Chen
Sci Rep. 2019; 9: 9437. Published online 2019 Jul 1. doi: 10.1038/s41598-019-46019-9
PMCID:
PMC6603037
AbstractArticlePDF–2.4M
19.
Ceruloplasmin Plays a Neuroprotective Role in Cerebral Ischemia
Fari Ryan, Juan G. Zarruk, Lena Lößlein, Samuel David
Front Neurosci. 2018; 12: 988. Published online 2019 Jan 8. doi: 10.3389/fnins.2018.00988
PMCID:
PMC6331473
AbstractArticlePDF–4.9M
20.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M

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