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Items: 1 to 20 of 65

1.
CMG helicase disassembly is essential and driven by two pathways in budding yeast
Cristian Polo Rivera, Tom D Deegan, Karim P M Labib
EMBO J. 2024 Sep; 43(18): 3818–3845. Published online 2024 Jul 22. doi: 10.1038/s44318-024-00161-x
PMCID:
PMC11405719
ArticlePDF–6.9M
2.
A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome
Ottavia Olson, Simone Pelliciari, Emma D Heron, Tom D Deegan
EMBO J. 2024 Sep; 43(18): 3846–3875. Published online 2024 Jul 22. doi: 10.1038/s44318-024-00168-4
PMCID:
PMC11405395
ArticlePDF–3.3M
3.
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
Aurora Yáñez-Vilches, Antonia M. Romero, Marta Barrientos-Moreno, Esther Cruz, Román González-Prieto, Sushma Sharma, Alfred C. O. Vertegaal, Félix Prado
PLoS Genet. 2024 May; 20(5): e1011148. Published online 2024 May 22. doi: 10.1371/journal.pgen.1011148
PMCID:
PMC11149843
ArticlePDF–3.5M
4.
Characterization of the dimeric CMG/pre-initiation complex and its transition into DNA replication forks
Lu Liu, Yue Zhang, Jingjing Zhang, Jian-Hua Wang, Qinhong Cao, Zhen Li, Judith L. Campbell, Meng-Qiu Dong, Huiqiang Lou
Cell Mol Life Sci. 2020 Aug; 77(15): 3041–3058. Published online 2019 Nov 15. doi: 10.1007/s00018-019-03333-9
PMCID:
PMC11104849
ArticlePDF–9.1M
5.
Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle
Michael J. O’Brien, Athar Ansari
Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968
PMCID:
PMC10872477
ArticlePDF–1.7M
6.
The social and structural architecture of the yeast protein interactome
André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann
Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5
PMCID:
PMC10700138
ArticlePDF–20M
7.
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability
Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai
Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108
PMCID:
PMC10551700
ArticlePDF–3.7M
8.
Synergism between CMG helicase and leading strand DNA polymerase at replication fork
Zhichun Xu, Jianrong Feng, Daqi Yu, Yunjing Huo, Xiaohui Ma, Wai Hei Lam, Zheng Liu, Xiang David Li, Toyotaka Ishibashi, Shangyu Dang, Yuanliang Zhai
Nat Commun. 2023; 14: 5849. Published online 2023 Sep 20. doi: 10.1038/s41467-023-41506-0
PMCID:
PMC10511561
ArticlePDF–5.3M
9.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
ArticlePDF–818K
10.
A conserved mechanism for regulating replisome disassembly in eukaryotes
Michael Jenkyn-Bedford, Morgan L. Jones, Yasemin Baris, Karim P. M. Labib, Giuseppe Cannone, Joseph T. P. Yeeles, Tom D. Deegan
Nature. 2021; 600(7890): 743–747. Published online 2021 Oct 26. doi: 10.1038/s41586-021-04145-3
PMCID:
PMC8695382
ArticlePDF–80M
11.
Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase—Pol ε Interaction
Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Shizuko Endo, Hiroyuki Araki, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska
Int J Mol Sci. 2020 Dec; 21(24): 9484. Published online 2020 Dec 13. doi: 10.3390/ijms21249484
PMCID:
PMC7762974
ArticlePDF–2.8M
12.
Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1
Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman
G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709
PMCID:
PMC7718751
ArticlePDF–1.2M
13.
Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication
Katy Stokes, Alicja Winczura, Boyuan Song, Giacomo De Piccoli, Daniel B Grabarczyk
Nucleic Acids Res. 2020 Aug 20; 48(14): 8128–8145. Published online 2020 Jun 25. doi: 10.1093/nar/gkaa541
PMCID:
PMC7641331
ArticlePDF–9.1M
14.
CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold
Tom D Deegan, Progya P Mukherjee, Ryo Fujisawa, Cristian Polo Rivera, Karim Labib
eLife. 2020; 9: e60371. Published online 2020 Aug 17. doi: 10.7554/eLife.60371
PMCID:
PMC7462611
ArticlePDF–4.9M
15.
DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis
Xiangzhou Meng, Lei Wei, Sujan Devbhandari, Tuo Zhang, Jenny Xiang, Dirk Remus, Xiaolan Zhao
Nat Commun. 2020; 11: 2437. Published online 2020 May 15. doi: 10.1038/s41467-020-16095-x
PMCID:
PMC7228970
ArticlePDF–2.7M
16.
Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability
Rowin Appanah, Emma Claire Lones, Umberto Aiello, Domenico Libri, Giacomo De Piccoli
Cell Rep. 2020 Feb 18; 30(7): 2094–2105.e9. Published online 2020 Feb 18. doi: 10.1016/j.celrep.2020.01.087
PMCID:
PMC7034062
Article
17.
Defects in the GINS complex increase the instability of repetitive sequences via a recombination-dependent mechanism
Malgorzata Jedrychowska, Milena Denkiewicz-Kruk, Malgorzata Alabrudzinska, Adrianna Skoneczna, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska
PLoS Genet. 2019 Dec; 15(12): e1008494. Published online 2019 Dec 9. doi: 10.1371/journal.pgen.1008494
PMCID:
PMC6922473
ArticlePDF–3.7M
18.
In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast
Progya P. Mukherjee, Karim P.M. Labib
Cell Rep. 2019 Sep 10; 28(11): 2777–2783.e4. Published online 2019 Sep 10. doi: 10.1016/j.celrep.2019.08.026
PMCID:
PMC6899518
Article
19.
The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε
Alicja Winczura, Rowin Appanah, Michael H. Tatham, Ronald T. Hay, Giacomo De Piccoli
PLoS Genet. 2019 Nov; 15(11): e1008427. Published online 2019 Nov 25. doi: 10.1371/journal.pgen.1008427
PMCID:
PMC6876773
ArticlePDF–2.8M
20.
Ctf4 organizes sister replisomes and Pol α into a replication factory
Zuanning Yuan, Roxana Georgescu, Ruda de Luna Almeida Santos, Daniel Zhang, Lin Bai, Nina Y Yao, Gongpu Zhao, Michael E O'Donnell, Huilin Li
eLife. 2019; 8: e47405. Published online 2019 Oct 7. doi: 10.7554/eLife.47405
PMCID:
PMC6800005
ArticlePDF–7.0M

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