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Select item 114484061.

Hepatitis B surface antigen impairs TLR4 signaling by upregulating A20 expression in monocytes

Cong Wang, Chenlu Huang, Yaming Li, Jinjin Bai, Kuangjie Zhao, Zhong Fang, Jieliang Chen

Microbiol Spectr. 2024 Oct; 12(10): e00909-24. Published online 2024 Sep 9. doi: 10.1128/spectrum.00909-24

PMCID:: PMC11448406

Abstract Article PDF–3.0M

Select item 112039762.

A20 in Kidney Transplantation and Autoimmunity

Andreas Kommer, Myriam Meineck, Paul Classen, Julia Weinmann-Menke

Int J Mol Sci. 2024 Jun; 25(12): 6628. Published online 2024 Jun 16. doi: 10.3390/ijms25126628

PMCID:: PMC11203976

Abstract Article PDF–1.0M

Select item 106765023.

The Prevalence of MYD88 L265P and TNFAIP3 Mutations and Their Correlations with Clinico-Hematological Profile in Egyptian Patients with Diffuse Large B Cell Lymphoma

Osama Elbaz, Rana M. Shaat, Hasan A. Abd El Ghaffar, Sameh Shamaa, Hanaa M. Abdel-Masseih, Nahla Anber, Metwaly Ibrahim Mortada

Asian Pac J Cancer Prev. 2023; 24(7): 2485–2491. doi: 10.31557/APJCP.2023.24.7.2485

PMCID:: PMC10676502

Abstract Article PDF–419K

Select item 106079904.

Association between PYTPN22 rs2476601, VEGF rs833070, TNFAIP3 rs6920220 Polymorphisms and Risk for Rheumatoid Arthritis in Early Undifferentiated Arthritis Patients: A Pilot Study

Regina Sakalyte, Sigita Stropuviene, Gabija Jasionyte, Loreta Bagdonaite, Algirdas Venalis

Medicina (Kaunas) 2023 Oct; 59(10): 1824. Published online 2023 Oct 13. doi: 10.3390/medicina59101824

PMCID:: PMC10607990

Abstract Article PDF–323K

Select item 105236655.

Human osteoarthritic articular cartilage stem cells suppress osteoclasts and improve subchondral bone remodeling in experimental knee osteoarthritis partially by releasing TNFAIP3

Zhi-Ling Li, Xiao-Tong Li, Rui-Cong Hao, Fei-Yan Wang, Yu-Xing Wang, Zhi-Dong Zhao, Pei-Lin Li, Bo-Feng Yin, Ning Mao, Li Ding, Heng Zhu

Stem Cell Res Ther. 2023; 14: 253. Published online 2023 Sep 27. doi: 10.1186/s13287-023-03411-7

PMCID:: PMC10523665

Abstract Article PDF–16M

Select item 104448276.

A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block “eat-me” signal

Min Luo, Xueping Wang, Shaocong Wu, Chuan Yang, Qiao Su, Lamei Huang, Kai Fu, Sainan An, Fachao Xie, Kenneth Kin Wah To, Fang Wang, Liwu Fu

Signal Transduct Target Ther. 2023; 8: 312. Published online 2023 Aug 23. doi: 10.1038/s41392-023-01545-x

PMCID:: PMC10444827

Abstract Article PDF–6.7M

Select item 102845997.

A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation

Elma El Khouri, Farah Diab, Camille Louvrier, Eman Assrawi, Aphrodite Daskalopoulou, Alexandre Nguyen, William Piterboth, Samuel Deshayes, Alexandra Desdoits, Bruno Copin, Florence Dastot Le Moal, Sonia Athina Karabina, Serge Amselem, Achille Aouba, Irina Giurgea

eLife. 2023; 12: e81280. Published online 2023 Jun 21. doi: 10.7554/eLife.81280

PMCID:: PMC10284599

Abstract Article PDF–4.1M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100909639.

Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis

Luxi Zou, Ling Sun, Ruixue Hua, Yu Wu, Linlin Sun, Ting Chen

J Innate Immun. 2023 Jan-Dec; 15(1): 428–441. Published online 2023 Mar 21. doi: 10.1159/000527624

PMCID:: PMC10090963

Abstract Article PDF–1.4M

Select item 997749910.

A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny

Ina Rohwedder, Lou Martha Wackerbarth, Kristina Heinig, Annamaria Ballweg, Johannes Altstätter, Myriam Ripphahn, Claudia Nussbaum, Melanie Salvermoser, Susanne Bierschenk, Tobias Straub, Matthias Gunzer, Marc Schmidt-Supprian, Thomas Kolben, Christian Schulz, Averil Ma, Barbara Walzog, Matthias Heinig, Markus Sperandio

JCI Insight. 2023 Feb 22; 8(4): e155968. Published online 2023 Feb 22. doi: 10.1172/jci.insight.155968

PMCID:: PMC9977499

Abstract Article PDF–3.9M

Select item 997213911.

TNFAIP3 mutation is an independent poor overall survival factor for patients with T‐cell acute lymphoblastic leukemia

Cunte Chen, Lingling Zhou, Lihua Zhu, Gengxin Luo, Liang Wang, Chengwu Zeng, Hongsheng Zhou, Yangqiu Li

Cancer Med. 2023 Feb; 12(4): 3952–3961. Published online 2022 Sep 3. doi: 10.1002/cam4.5196

PMCID:: PMC9972139

Abstract Article PDF–9.0M

Select item 988113112.

ZNF212 promotes genomic integrity through direct interaction with TRAIP

Hee Jin Chung, Joo Rak Lee, Tae Moon Kim, Soomi Kim, Kibeom Park, Myung-Jin Kim, Eunyoung Jung, Subin Kim, Eun A Lee, Jae Sun Ra, Sunyoung Hwang, Ja Yil Lee, Orlando D Schärer, Yonghwan Kim, Kyungjae Myung, Hongtae Kim

Nucleic Acids Res. 2023 Jan 25; 51(2): 631–649. Published online 2023 Jan 3. doi: 10.1093/nar/gkac1226

PMCID:: PMC9881131

Abstract Article PDF–4.1M

Select item 979798813.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 970452714.

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen

Biochem J. 2022 Oct 28; 479(20): 2195–2216. Published online 2022 Oct 21. doi: 10.1042/BCJ20220401

PMCID:: PMC9704527

Abstract Article PDF–7.7M

Select item 952163215.

GSTO1 confers drug resistance in HCT-116 colon cancer cells through an interaction with TNFαIP3/A20

Souren Paul, Monika Bhardwaj, Sun Chul Kang

Int J Oncol. 2022 Nov; 61(5): 136. Published online 2022 Sep 21. doi: 10.3892/ijo.2022.5426

PMCID:: PMC9521632

Abstract Article PDF–3.4M

Select item 944671216.

TNFAIP3 mutation causing haploinsufficiency of A20 with a hemophagocytic lymphohistiocytosis phenotype: a report of two cases

Nahid Aslani, Kosar Asnaashari, Nima Parvaneh, Mohammad Shahrooei, Maryam Sotoudeh-Anvari, Farhad Shahram, Vahid Ziaee

Pediatr Rheumatol Online J. 2022; 20: 78. Published online 2022 Sep 5. doi: 10.1186/s12969-022-00735-1

PMCID:: PMC9446712

Abstract Article PDF–694K

Select item 934331117.

USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection

Phatcharida Jantaree, Supattra Chaithongyot, Olga Sokolova, Michael Naumann

Cell Mol Life Sci. 2022 Aug; 79(8): 461. Published online 2022 Aug 1. doi: 10.1007/s00018-022-04489-7

PMCID:: PMC9343311

Abstract Article PDF–2.2M

Select item 930985218.

Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Lilla ERDEI, Beáta Szilvia BOLLA, Renáta BOZÓ, Gábor TAX, Edit URBÁN, Katalin BURIÁN, Lajos KEMÉNY, Kornélia SZABÓ

Acta Derm Venereol. 2021; 101(1): 1470. Published online 2021 Jan 13. doi: 10.2340/00015555-3707

PMCID:: PMC9309852

Abstract Article PDF–4.3M

Select item 926261419.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538