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Select item 116156931.

Effects of glucokinase haploinsufficiency on the pancreatic β‐cell mass and function of long‐term high‐fat, high‐sucrose diet‐fed mice

Ikumi Shigesawa, Akinobu Nakamura, Yuki Yamauchi, Shinichiro Kawata, Asuka Miyazaki, Hiroshi Nomoto, Hiraku Kameda, Yasuo Terauchi, Tatsuya Atsumi

J Diabetes Investig. 2024 Dec; 15(12): 1732–1742. Published online 2024 Sep 21. doi: 10.1111/jdi.14307

PMCID:: PMC11615693

Abstract Article PDF–6.5M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 101914414.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 99382165.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 96177816.

Alzheimer’s disease/dementia-associated brain pathology in aging DPP6-KO mice

Lin Lin, Ronald S. Petralia, Lynne Holtzclaw, Ya-Xian Wang, Daniel Abebe, Dax A. Hoffman

Neurobiol Dis. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: Neurobiol Dis. 2022 Nov; 174: 105887. Published online 2022 Oct 6. doi: 10.1016/j.nbd.2022.105887

PMCID:: PMC9617781

Abstract Article PDF–6.3M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76821099.

A novel structure associated with aging is augmented in the DPP6-KO mouse brain

Lin Lin, Ronald S. Petralia, Ross Lake, Ya-Xian Wang, Dax A. Hoffman

Acta Neuropathol Commun. 2020; 8: 197. Published online 2020 Nov 23. doi: 10.1186/s40478-020-01065-7

PMCID:: PMC7682109

Abstract Article PDF–4.9M

Select item 740631710.

Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor

Keri A. Drake, Christopher P. Chaney, Amrita Das, Priti Roy, Callie S. Kwartler, Dinesh Rakheja, Thomas J. Carroll

Development. 2020 Nov 1; 147(21): dev189597. Published online 2020 Jul 31. doi: 10.1242/dev.189597

PMCID:: PMC7406317

Abstract Article

Select item 588488511.

DPP6 Loss Impacts Hippocampal Synaptic Development and Induces Behavioral Impairments in Recognition, Learning and Memory

Lin Lin, Jonathan G. Murphy, Rose-Marie Karlsson, Ronald S. Petralia, Jakob J. Gutzmann, Daniel Abebe, Ya-Xian Wang, Heather A. Cameron, Dax A. Hoffman

Front Cell Neurosci. 2018; 12: 84. Published online 2018 Mar 29. doi: 10.3389/fncel.2018.00084

PMCID:: PMC5884885

Abstract Article PDF–3.0M

Select item 500488312.

Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity

Iain Williamson, Laura A. Lettice, Robert E. Hill, Wendy A. Bickmore

Development. 2016 Aug 15; 143(16): 2994–3001. doi: 10.1242/dev.139188

PMCID:: PMC5004883

Abstract Article

Select item 387357713.

The Prion Protein Modulates A-type K⁺ Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6

Robert C. C. Mercer, Li Ma, Joel C. Watts, Robert Strome, Serene Wohlgemuth, Jing Yang, Neil R. Cashman, Michael B. Coulthart, Gerold Schmitt-Ulms, Jack H. Jhamandas, David Westaway

J Biol Chem. 2013 Dec 27; 288(52): 37241–37255. Published online 2013 Nov 13. doi: 10.1074/jbc.M113.488650

PMCID:: PMC3873577

Abstract Article PDF–2.4M

Select item 377561114.

DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development

Lin Lin, Wei Sun, Ben Throesch, Faith Kung, Jameice T Decoster, Cory J Berner, Richard E. Cheney, Bernardo Rudy, Dax A Hoffman

Nat Commun. Author manuscript; available in PMC 2014 Feb 5.

Published in final edited form as: Nat Commun. 2013; 4: 2270. doi: 10.1038/ncomms3270

PMCID:: PMC3775611

Abstract Article PDF–2.5M

Select item 375888515.

The Dipeptidyl-Peptidase-Like Protein DPP6 Determines the Unitary Conductance of Neuronal Kv4.2 Channels

Yuri A. Kaulin, José A. De Santiago-Castillo, Carmen A. Rocha, Marcela S. Nadal, Bernardo Rudy, Manuel Covarrubias

J Neurosci. 2009 Mar 11; 29(10): 3242–3251. doi: 10.1523/JNEUROSCI.4767-08.2009

PMCID:: PMC3758885

Abstract Article PDF–1.8M

Select item 367803416.

Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K⁺ channels

Jon K Maffie, Elena Dvoretskova, Pierre Edouard Bougis, Marie-France Martin-Eauclaire, Bernardo Rudy

J Physiol. 2013 May 15; 591(Pt 10): 2419–2427. Published online 2013 Feb 25. doi: 10.1113/jphysiol.2012.248831

PMCID:: PMC3678034

Abstract Article PDF–837K

Select item 362190517.

A New TASK for Dipeptidyl Peptidase-like Protein 6

Brian M. Nadin, Paul J. Pfaffinger

PLoS One. 2013; 8(4): e60831. Published online 2013 Apr 9. doi: 10.1371/journal.pone.0060831

PMCID:: PMC3621905

Abstract Article PDF–2.5M

Select item 356702418.

Epigenetic Regulation of Dpp6 Expression by Dnmt3b and Its Novel Role in the Inhibition of RA Induced Neuronal Differentiation of P19 Cells

Muhammad Abid Sheikh, Yousra Saeed Malik, Huali Yu, Mingming Lai, Xingzhi Wang, Xiaojuan Zhu

PLoS One. 2013; 8(2): e55826. Published online 2013 Feb 7. doi: 10.1371/journal.pone.0055826

PMCID:: PMC3567024

Abstract Article PDF–2.1M

Select item 330878319.

Augmentation of Kv4.2-encoded Currents by Accessory Dipeptidyl Peptidase 6 and 10 Subunits Reflects Selective Cell Surface Kv4.2 Protein Stabilization

Nicholas C. Foeger, Aaron J. Norris, Lisa M. Wren, Jeanne M. Nerbonne

J Biol Chem. 2012 Mar 16; 287(12): 9640–9650. Published online 2012 Feb 6. doi: 10.1074/jbc.M111.324574

PMCID:: PMC3308783

Abstract Article PDF–2.1M

Select item 318423720.

DPP6 establishes the A-type K⁺ current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons

Wei Sun, Jon K. Maffie, Lin Lin, Ronald S. Petralia, Bernardo Rudy, Dax A. Hoffman

Neuron. Author manuscript; available in PMC 2012 Sep 22.

Published in final edited form as: Neuron. 2011 Sep 22; 71(6): 1102–1115. Published online 2011 Sep 21. doi: 10.1016/j.neuron.2011.08.008

PMCID:: PMC3184237

Abstract Article PDF–3.9M

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