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Select item 109217931.

Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression

Cuncan Deng, Mingyu Huo, Hongwu Chu, Xiaomei Zhuang, Guofei Deng, Wenchao Li, Hongfa Wei, Leli Zeng, Yulong He, Huashan Liu, Jia Li, Changhua Zhang, Hengxing Chen

Mol Cancer. 2024; 23: 49. Published online 2024 Mar 8. doi: 10.1186/s12943-024-01966-4

PMCID:: PMC10921793

Abstract Article PDF–2.6M

Select item 102841172.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 90958803.

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis

Dae Gyu Kim, Yongseok Choi, Yuno Lee, Semi Lim, Jiwon Kong, JaeHa Song, Younah Roh, Dipesh S. Harmalkar, Kwanshik Lee, Ja-il Goo, Hye Young Cho, Ameeq Ul Mushtaq, Jihye Lee, Song Hwa Park, Doyeun Kim, Byung Soh Min, Kang Young Lee, Young Ho Jeon, Sunkyung Lee, Kyeong Lee, Sunghoon Kim

Nat Commun. 2022; 13: 2572. Published online 2022 May 11. doi: 10.1038/s41467-022-30149-2

PMCID:: PMC9095880

Abstract Article PDF–2.1M

Select item 83641814.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81579576.

AP-3–dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells

Seunghyi Kook, Ping Wang, Shufang Meng, Christopher S. Jetter, Jennifer M. S. Sucre, John T. Benjamin, Jason J. Gokey, Hayley A. Hanby, Alexa Jaume, Laura Goetzl, Michael S. Marks, Susan H. Guttentag

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2025208118. Published online 2021 May 14. doi: 10.1073/pnas.2025208118

PMCID:: PMC8157957

Abstract Article PDF–1.9M

Select item 63737417.

Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets

Weidong Jing, Mehmet Yabas, Angelika Bröer, Lucy Coupland, Elizabeth E. Gardiner, Anselm Enders, Stefan Bröer

Blood Adv. 2019 Feb 12; 3(3): 219–229. Published online 2019 Jan 23. doi: 10.1182/bloodadvances.2018023473

PMCID:: PMC6373741

Abstract Article PDF–1.7M

Select item 63350998.

Blood-Brain Barrier: From Physiology to Disease and Back

Melanie D. Sweeney, Zhen Zhao, Axel Montagne, Amy R. Nelson, Berislav V. Zlokovic

Physiol Rev. 2019 Jan 1; 99(1): 21–78. Published online 2018 Oct 3. doi: 10.1152/physrev.00050.2017

PMCID:: PMC6335099

Abstract Article

Select item 62564299.

Over-Expression of ATPase II Alleviates Ethanol-Induced Hepatocyte Injury in HL-7702 Cells

Qing Li, Yan Yang, Ying Liu

Med Sci Monit. 2018; 24: 8372–8382. Published online 2018 Nov 20. doi: 10.12659/MSM.910254

PMCID:: PMC6256429

Abstract Article PDF–1.3M

Select item 582692610.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 566588711.

Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

Tatsuyuki Matsudaira, Kojiro Mukai, Taishin Noguchi, Junya Hasegawa, Tomohisa Hatta, Shun-ichiro Iemura, Tohru Natsume, Norio Miyamura, Hiroshi Nishina, Jun Nakayama, Kentaro Semba, Takuya Tomita, Shigeo Murata, Hiroyuki Arai, Tomohiko Taguchi

Nat Commun. 2017; 8: 1246. Published online 2017 Nov 1. doi: 10.1038/s41467-017-01255-3

PMCID:: PMC5665887

Abstract Article PDF–4.3M

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 483187313.

An improved smaller biotin ligase for BioID proximity labeling

Dae In Kim, Samuel C. Jensen, Kyle A. Noble, Birendra KC, Kenneth H. Roux, Khatereh Motamedchaboki, Kyle J. Roux

Mol Biol Cell. 2016 Apr 15; 27(8): 1188–1196. doi: 10.1091/mbc.E15-12-0844

PMCID:: PMC4831873

Abstract Article PDF–2.1M

Select item 436503514.

Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

Shoken Lee, Yasunori Uchida, Jiao Wang, Tatsuyuki Matsudaira, Takatoshi Nakagawa, Takuma Kishimoto, Kojiro Mukai, Takehiko Inaba, Toshihide Kobayashi, Robert S Molday, Tomohiko Taguchi, Hiroyuki Arai

EMBO J. 2015 Mar 4; 34(5): 669–688. Published online 2015 Jan 16. doi: 10.15252/embj.201489703

PMCID:: PMC4365035

Abstract Article PDF–2.5M

Select item 430502815.

Genetic Analysis of the Pathogenic Molecular Sub-phenotype Interferon Alpha Identifies Multiple Novel Loci Involved in Systemic Lupus Erythematosus

Silvia N. Kariuki, Yogita Ghodke-Puranik, Jessica M. Dorschner, Beverly S. Chrabot, Jennifer A. Kelly, Betty P. Tsao, Robert P. Kimberly, Marta E. Alarcón-Riquelme, Chaim O. Jacob, Lindsey A. Criswell, Kathy L. Sivils, Carl D. Langefeld, John B. Harley, Andrew D. Skol, Timothy B. Niewold

Genes Immun. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Genes Immun. 2015 Jan-Feb; 16(1): 15–23. Published online 2014 Oct 23. doi: 10.1038/gene.2014.57

PMCID:: PMC4305028

Abstract Article PDF–1.2M

Select item 417058516.

Genome-Wide Analysis of Polymorphisms Associated with Cytokine Responses in Smallpox Vaccine Recipients

Richard B. Kennedy, Inna G. Ovsyannikova, V. Shane Pankratz, Iana H. Haralambieva, Robert A. Vierkant, Gregory A. Poland

Hum Genet. Author manuscript; available in PMC 2014 Sep 22.

Published in final edited form as: Hum Genet. 2012 Sep; 131(9): 1403–1421. Published online 2012 May 19. doi: 10.1007/s00439-012-1174-2

PMCID:: PMC4170585

Abstract Article PDF–594K

Select item 377350517.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561