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Items: 1 to 20 of 30

1.
ELF4 contributes to esophageal squamous cell carcinoma growth and metastasis by augmenting cancer stemness via FUT9: Role of ELF4 in esophageal squamous cell carcinoma
Aiping Xu, Mingchuang Sun, Zhaoxing Li, Yuan Chu, Kang Fang, Yunwei Zhang, Jingjing Lian, Li Zhang, Tao Chen, Meidong Xu
Acta Biochim Biophys Sin (Shanghai) 2024 Jan 25; 56(1): 129–139. Published online 2023 Sep 7. doi: 10.3724/abbs.2023225
PMCID:
PMC10875363
AbstractArticlePDF–2.6M
2.
Reciprocal regulation of lncRNA MEF and c-Myc drives colorectal cancer tumorigenesis
Shuang Wu, Xiangyu Dai, Zhipu Zhu, Dianhui Fan, Su Jiang, Yi Dong, Bing Chen, Qi Xie, Zhihui Yao, Qun Li, Rick Francis Thorne, Yao Lu, Hao Gu, Wanglai Hu
Neoplasia. 2024 Mar; 49: 100971. Published online 2024 Feb 1. doi: 10.1016/j.neo.2024.100971
PMCID:
PMC10847691
AbstractArticlePDF–6.5M
3.
ELF4 is a critical component of a miRNA-transcription factor network and is a bridge regulator of glioblastoma receptor signaling and lipid dynamics
Adam Kosti, Jennifer Chiou, Gabriela D A Guardia, Xiufen Lei, Henriette Balinda, Tesha Landry, Xiyuan Lu, Mei Qiao, Andrea Gilbert, Andrew Brenner, Pedro A F Galante, Stefano Tiziani, Luiz O F Penalva
Neuro Oncol. 2023 Mar; 25(3): 459–470. Published online 2022 Jul 21. doi: 10.1093/neuonc/noac179
PMCID:
PMC10013642
AbstractArticlePDF–5.2M
4.
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC
Xilang Chen, Jie Chen, Weibo Feng, Wenjie Huang, Guodong Wang, Mengyu Sun, Xiangyuan Luo, Yijun Wang, Yongzhan Nie, Daiming Fan, Kaichun Wu, Limin Xia
Theranostics. 2023; 13(4): 1401–1418. Published online 2023 Feb 22. doi: 10.7150/thno.82269
PMCID:
PMC10008733
AbstractArticlePDF–16M
5.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
6.
An ELF4 hypomorphic variant results in NK cell deficiency
Sandra Andrea Salinas, Emily M. Mace, Matilde I. Conte, Chun Shik Park, Yu Li, Joshua I. Rosario-Sepulveda, Sanjana Mahapatra, Emily K. Moore, Evelyn R. Hernandez, Ivan K. Chinn, Abigail E. Reed, Barclay J. Lee, Alexander Frumovitz, Richard A. Gibbs, Jennifer E. Posey, Lisa R. Forbes Satter, Akaluck Thatayatikom, Eric J. Allenspach, Theodore G. Wensel, James R. Lupski, H. Daniel Lacorazza, Jordan S. Orange
JCI Insight. 2022 Dec 8; 7(23): e155481. Published online 2022 Dec 8. doi: 10.1172/jci.insight.155481
PMCID:
PMC9746917
AbstractArticlePDF–7.0M
7.
Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation
Paul M. Tyler, Molly L. Bucklin, Mengting Zhao, Timothy J. Maher, Andrew J. Rice, Weizhen Ji, Neil Warner, Jie Pan, Raffaella Morotti, Paul McCarthy, Anne Griffiths, Annemarie M.C. van Rossum, Iris H.I.M. Hollink, Virgil A.S.H. Dalm, Jason Catanzaro, Saquib A. Lakhani, Aleixo M. Muise, Carrie L. Lucas
Nat Immunol. Author manuscript; available in PMC 2022 Apr 6.
Published in final edited form as: Nat Immunol. 2021 Sep; 22(9): 1118–1126. Published online 2021 Jul 29. doi: 10.1038/s41590-021-00984-4
PMCID:
PMC8985851
AbstractArticlePDF–3.7M
8.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
9.
ELF4通过激活Akt通路促进胰岛素瘤细胞增殖并抑制细胞凋亡
卫 国红, 王 利, 万 学思, 谭 泳谣
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Aug 31; 41(9): 1329–1333. Chinese. doi: 10.12122/j.issn.1673-4254.2021.09.06
PMCID:
PMC8526310
AbstractArticlePDF–1.4M
10.
High ELF4 expression in human cancers is associated with worse disease outcomes and increased resistance to anticancer drugs
Doris Kafita, Victor Daka, Panji Nkhoma, Mildred Zulu, Ephraim Zulu, Rabecca Tembo, Zifa Ngwira, Florence Mwaba, Musalula Sinkala, Sody Munsaka
PLoS One. 2021; 16(4): e0248984. Published online 2021 Apr 9. doi: 10.1371/journal.pone.0248984
PMCID:
PMC8034723
AbstractArticlePDF–2.1M
11.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
12.
Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma
Karen Man‐Fong Sze, Daniel Wai‐Hung Ho, Yung‐Tuen Chiu, Yu‐Man Tsui, Lo‐Kong Chan, Joyce Man‐Fong Lee, Kenneth Siu‐Ho Chok, Albert Chi‐Yan Chan, Chung‐Ngai Tang, Victor Wai‐Lun Tang, Irene Lai‐Oi Lo, Derek Tsz‐Wai Yau, Tan‐To Cheung, Irene Oi‐Lin Ng
Hepatology. 2021 Jan; 73(1): 23–40. Published online 2020 Nov 26. doi: 10.1002/hep.31231
PMCID:
PMC7898544
AbstractArticlePDF–2.2M
13.
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
Jonathan Poh, Amy H. Ponsford, James Boyd, Jonathan Woodsmith, Ulrich Stelzl, Erich Wanker, Nicholas Harper, David MacEwan, Christopher M. Sanderson
Redox Biol. 2020 Oct; 37: 101686. Published online 2020 Aug 20. doi: 10.1016/j.redox.2020.101686
PMCID:
PMC7490560
AbstractArticlePDF–8.6M
14.
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state
Adam Kosti, Liqin Du, Haridha Shivram, Mei Qiao, Suzanne Burns, Juan Gabriel Garcia, Alexander Pertsemlidis, Vishwanath R. Iyer, Erzsebet Kokovay, Luiz O.F. Penalva
Mol Cancer Res. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Mol Cancer Res. 2020 Jan; 18(1): 68–78. Published online 2019 Oct 17. doi: 10.1158/1541-7786.MCR-19-0187
PMCID:
PMC6942226
AbstractArticlePDF–3.1M
15.
H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids
Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth
Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9
PMCID:
PMC6420097
ArticlePDF–1.7M
16.
An improved smaller biotin ligase for BioID proximity labeling
Dae In Kim, Samuel C. Jensen, Kyle A. Noble, Birendra KC, Kenneth H. Roux, Khatereh Motamedchaboki, Kyle J. Roux
Mol Biol Cell. 2016 Apr 15; 27(8): 1188–1196. doi: 10.1091/mbc.E15-12-0844
PMCID:
PMC4831873
AbstractArticlePDF–2.1M
17.
The Transcription Factor MEF/Elf4 Is Dually Modulated by p53-MDM2 Axis and MEF-MDM2 Autoregulatory Mechanism
Mary Ann Suico, Ryosuke Fukuda, Rui Miyakita, Kosuke Koyama, Manabu Taura, Tsuyoshi Shuto, Hirofumi Kai
J Biol Chem. 2014 Sep 19; 289(38): 26143–26154. Published online 2014 Jul 31. doi: 10.1074/jbc.M114.580209
PMCID:
PMC4176203
AbstractArticlePDF–2.1M
18.
HIV-1 gp120 impairs B cell proliferation by inducing TGF-ß1 production and FcRL4 expression
Katija Jelicic, Raffaello Cimbro, Fatima Nawaz, Da Wei Huang, Xin Zheng, Jun Yang, Richard A. Lempicki, Massimiliano Pascuccio, Donald Van Ryk, Catherine Schwing, Joseph Hiatt, Noreen Okwara, Danlan Wei, Gregg Roby, Antonio David, Young Hwang, II, John H. Kehrl, James Arthos, Claudia Cicala, Anthony S. Fauci
Nat Immunol. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: Nat Immunol. 2013 Dec; 14(12): 1256–1265. Published online 2013 Oct 27. doi: 10.1038/ni.2746
PMCID:
PMC3870659
AbstractArticlePDF–1.4M
19.
MEF promotes stemness in the pathogenesis of gliomas
Elena Bazzoli, Teodoro Pulvirenti, Moritz C. Oberstadt, Fabiana Perna, Boyoung Wee, Nikolaus Schultz, Jason T. Huse, Elena I. Fomchenko, Francesca Voza, Viviane Tabar, Cameron W. Brennan, Lisa M. DeAngelis, Stephen D. Nimer, Eric C. Holland, Massimo Squatrito
Cell Stem Cell. Author manuscript; available in PMC 2013 Dec 7.
Published in final edited form as: Cell Stem Cell. 2012 Dec 7; 11(6): 10.1016/j.stem.2012.09.012. doi: 10.1016/j.stem.2012.09.012
PMCID:
PMC3812924
AbstractArticlePDF–642K
20.
Mutations in the Nucleolar Phosphoprotein, Nucleophosmin, Promote the Expression of the Oncogenic Transcription Factor MEF/ELF4 in Leukemia Cells and Potentiates Transformation
Koji Ando, Hideki Tsushima, Emi Matsuo, Kensuke Horio, Shinya Tominaga-Sato, Daisuke Imanishi, Yoshitaka Imaizumi, Masako Iwanaga, Hidehiro Itonaga, Shinichiro Yoshida, Tomoko Hata, Ryozo Moriuchi, Hitoshi Kiyoi, Stephen Nimer, Hiroyuki Mano, Tomoki Naoe, Masao Tomonaga, Yasushi Miyazaki
J Biol Chem. 2013 Mar 29; 288(13): 9457–9467. Published online 2013 Feb 7. doi: 10.1074/jbc.M112.415703
PMCID:
PMC3611015
AbstractArticlePDF–1.7M

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