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Select item 107988581.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977003.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922104.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 102333685.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98363486.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 96309867.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92860238.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 857691710.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L. Gupta, Jr.

J Cell Biol. 2021 Dec 6; 220(12): e202010155. Published online 2021 Nov 5. doi: 10.1083/jcb.202010155

PMCID:: PMC8576917

Abstract Article PDF–7.4M

Select item 854891611.

Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels

Michal Eisenberg-Bord, Naama Zung, Javier Collado, Layla Drwesh, Emma J. Fenech, Amir Fadel, Nili Dezorella, Yury S. Bykov, Doron Rapaport, Ruben Fernandez-Busnadiego, Maya Schuldiner

J Cell Biol. 2021 Nov 1; 220(11): e202104100. Published online 2021 Oct 25. doi: 10.1083/jcb.202104100

PMCID:: PMC8548916

Abstract Article PDF–6.5M

Select item 852129912.

Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline‐auxotroph yeast

Xue Bao, Martijn C Koorengevel, Marian J A Groot Koerkamp, Amir Homavar, Amrah Weijn, Stefan Crielaard, Mike F Renne, Joseph H Lorent, Willie JC Geerts, Michal A Surma, Muriel Mari, Frank C P Holstege, Christian Klose, Anton I P M de Kroon

EMBO J. 2021 Oct 18; 40(20): e107966. Published online 2021 Sep 14. doi: 10.15252/embj.2021107966

PMCID:: PMC8521299

Abstract Article PDF–4.1M

Select item 826033113.

Water soluble lipid precursor contaminants in yeast culture medium ingredients

Mike F Renne, Xue Bao, Anton I P M de Kroon

FEMS Yeast Res. 2020 Aug; 20(5): foaa029. Published online 2020 Jun 27. doi: 10.1093/femsyr/foaa029

PMCID:: PMC8260331

Abstract Article PDF–956K

Select item 805418914.

Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine

Donna M. Iadarola, Alaumy Joshi, Cameron B. Caldwell, Vishal M. Gohil

J Biol Chem. 2021 Jan-Jun; 296: 100539. Published online 2021 Mar 12. doi: 10.1016/j.jbc.2021.100539

PMCID:: PMC8054189

Abstract Article PDF–901K

Select item 794911615.

Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling

Akinori Eiyama, Mari J. Aaltonen, Hendrik Nolte, Takashi Tatsuta, Thomas Langer

J Biol Chem. 2021 Jan-Jun; 296: 100335. Published online 2021 Jan 23. doi: 10.1016/j.jbc.2021.100335

PMCID:: PMC7949116

Abstract Article PDF–1.8M

Select item 771875116.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 766412217.

The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Teresa M. Buck, Xuemei Zeng, Pamela S. Cantrell, Richard T. Cattley, Zikri Hasanbasri, Megan E. Yates, Diep Nguyen, Nathan A. Yates, Jeffrey L. Brodsky

Mol Cell Proteomics. 2020 Nov; 19(11): 1896–1909. Published online 2020 Aug 31. doi: 10.1074/mcp.RA120.002050

PMCID:: PMC7664122

Abstract Article PDF–1.2M

Select item 727317718.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 726171819.

Growth-Regulated Hsp70 Phosphorylation Regulates Stress Responses and Prion Maintenance

Chung-Hsuan Kao, Seung W. Ryu, Min J. Kim, Xuemei Wen, Oshadi Wimalarathne, Tanya T. Paull

Mol Cell Biol. 2020 Jun; 40(12): e00628-19. Prepublished online 2020 Mar 23. Published online 2020 May 28. doi: 10.1128/MCB.00628-19

PMCID:: PMC7261718

Abstract Article PDF–3.4M

Select item 719238820.

Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca²⁺-dependent phosphatase

Gerardo R. Corradi, Luciana R. Mazzitelli, Guido D. Petrovich, Paula Grenon, Danny M. Sørensen, Michael Palmgren, Felicitas de Tezanos Pinto, Hugo P. Adamo

PLoS One. 2020; 15(4): e0232476. Published online 2020 Apr 30. doi: 10.1371/journal.pone.0232476