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Select item 110893641.

Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation

Alice Shaam Al Abed, Tiarne Vickie Allen, Noorya Yasmin Ahmed, Azza Sellami, Yovina Sontani, Elise Caitlin Rawlinson, Aline Marighetto, Aline Desmedt, Nathalie Dehorter

iScience. 2024 May 17; 27(5): 109747. Published online 2024 Apr 16. doi: 10.1016/j.isci.2024.109747

PMCID:: PMC11089364

Abstract Article PDF–3.3M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109047593.

Contactin-associated protein-like 2 (CNTNAP2) mutations impair the essential α-secretase cleavages, leading to autism-like phenotypes

Qing Zhang, Mengen Xing, Zhengkai Bao, Lu Xu, Yang Bai, Wanqi Chen, Wenhao Pan, Fang Cai, Qunxian Wang, Shipeng Guo, Jing Zhang, Zhe Wang, Yili Wu, Yun Zhang, Jia-Da Li, Weihong Song

Signal Transduct Target Ther. 2024; 9: 51. Published online 2024 Mar 1. doi: 10.1038/s41392-024-01768-6

PMCID:: PMC10904759

Abstract Article PDF–5.1M

Select item 107669754.

Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain

Manish Kumar Tripathi, Shashank Kumar Ojha, Maryam Kartawy, Igor Khaliulin, Wajeha Hamoudi, Haitham Amal

Sci Rep. 2024; 14: 10. Published online 2024 Jan 4. doi: 10.1038/s41598-023-50248-4

PMCID:: PMC10766975

Abstract Article PDF–2.8M

Select item 106654865.

Beatriz G. Robinson, Beau A. Oster, Keiramarie Robertson, Julia A. Kaltschmidt

Front Neurosci. 2023; 17: 1287057. Published online 2023 Nov 9. doi: 10.3389/fnins.2023.1287057

PMCID:: PMC10665486

Abstract Article PDF–3.7M

Select item 105943496.

Long wavelength light reduces the negative consequences of dim light at night

Huei-Bin Wang, David Zhou, Shu Hon Christopher Luk, Hye In Cha, Amanda Mac, Rim Chae, Anna Matynia, Ben Harrison, Sina Afshari, Gene D. Block, Cristina A. Ghiani, Christopher S. Colwell

Neurobiol Dis. Author manuscript; available in PMC 2023 Oct 24.

Published in final edited form as: Neurobiol Dis. 2023 Jan; 176: 105944. Published online 2022 Dec 6. doi: 10.1016/j.nbd.2022.105944

PMCID:: PMC10594349

Abstract Article PDF–2.1M

Select item 104708497.

The Novel Somatosensory Nose-Poke Adapted Paradigm (SNAP) Is an Effective Tool to Assess Differences in Tactile Sensory Preferences in Autistic-Like Mice

Matthew S. Binder, Angelique Bordey

eNeuro. 2023 Aug; 10(8): ENEURO.0478-22.2023. Prepublished online 2023 Aug 18. Published online 2023 Aug 28. doi: 10.1523/ENEURO.0478-22.2023

PMCID:: PMC10470849

Abstract Article PDF–944K

Select item 104276888.

Sexual dimorphism in the social behaviour of Cntnap2-null mice correlates with disrupted synaptic connectivity and increased microglial activity in the anterior cingulate cortex

Matt S. Dawson, Kevin Gordon-Fleet, Lingxin Yan, Vera Tardos, Huanying He, Kwong Mui, Smriti Nawani, Zeinab Asgarian, Marco Catani, Cathy Fernandes, Uwe Drescher

Commun Biol. 2023; 6: 846. Published online 2023 Aug 15. doi: 10.1038/s42003-023-05215-0

PMCID:: PMC10427688

Abstract Article PDF–2.9M

Select item 102397539.

CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors

Jing Zhang, Fang Cai, Renbin Lu, Xiaoliang Xing, Lu Xu, Kunyang Wu, Zishan Gong, Qing Zhang, Yun Zhang, Mengen Xing, Weihong Song, Jia-Da Li

Signal Transduct Target Ther. 2023; 8: 219. Published online 2023 Jun 5. doi: 10.1038/s41392-023-01431-6

PMCID:: PMC10239753

Abstract Article PDF–3.2M

Select item 1022563910.

Comparing synaptic proteomes across five mouse models for autism reveals converging molecular similarities including deficits in oxidative phosphorylation and Rho GTPase signaling

Abigail U. Carbonell, Carmen Freire-Cobo, Ilana V. Deyneko, Saunil Dobariya, Hediye Erdjument-Bromage, Amy E. Clipperton-Allen, Damon T. Page, Thomas A. Neubert, Bryen A. Jordan

Front Aging Neurosci. 2023; 15: 1152562. Published online 2023 May 15. doi: 10.3389/fnagi.2023.1152562

PMCID:: PMC10225639

Abstract Article PDF–2.0M

Select item 1004326611.

Behavioral regulation by perineuronal nets in the prefrontal cortex of the CNTNAP2 mouse model of autism spectrum disorder

Tanya Gandhi, Chin-Chi Liu, Tolulope T. Adeyelu, Cade R. Canepa, Charles C. Lee

Front Behav Neurosci. 2023; 17: 1114789. Published online 2023 Mar 14. doi: 10.3389/fnbeh.2023.1114789

PMCID:: PMC10043266

Abstract Article PDF–3.9M

Select item 993010412.

Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder

Noorya Yasmin Ahmed, Rhys Knowles, Lixinyu Liu, Yiming Yan, Xiaohan Li, Ulrike Schumann, Yumeng Wang, Yovina Sontani, Nathan Reynolds, Riccardo Natoli, Jiayu Wen, Isabel Del Pino, Da Mi, Nathalie Dehorter

Front Cell Dev Biol. 2023; 11: 1112062. Published online 2023 Feb 1. doi: 10.3389/fcell.2023.1112062

PMCID:: PMC9930104

Abstract Article PDF–3.5M

Select item 992286913.

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse

Carmen Cifuentes-Diaz, Giorgia Canali, Marta Garcia, Mélanie Druart, Taylor Manett, Mythili Savariradjane, Camille Guillaume, Corentin Le Magueresse, Laurence Goutebroze

Front Neurosci. 2023; 17: 1100121. Published online 2023 Jan 30. doi: 10.3389/fnins.2023.1100121

PMCID:: PMC9922869

Abstract Article PDF–6.4M

Select item 990854414.

Cntnap2-dependent molecular networks in autism spectrum disorder revealed through an integrative multi-omics analysis

Wooyoung Eric Jang, Ji Hwan Park, Gaeun Park, Geul Bang, Chan Hyun Na, Jin Young Kim, Kwang-Youl Kim, Kwang Pyo Kim, Chan Young Shin, Joon-Yong An, Yong-Seok Lee, Min-Sik Kim

Mol Psychiatry. 2023; 28(2): 810–821. Published online 2022 Oct 17. doi: 10.1038/s41380-022-01822-1

PMCID:: PMC9908544

Abstract Article PDF–2.4M

Select item 948988115.

From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems

Cornelia Carey, Nisha Singh, Joel T. Dunn, Teresa Sementa, Maria Andreina Mendez, Hester Velthuis, Andreia C. Pereira, Charlotte Marie Pretzsch, Jamie Horder, Stefan Hader, David J. Lythgoe, Diana-Georgina Rotaru, Anthony Gee, Diana Cash, Mattia Veronese, Declan Murphy, Grainne McAlonan

Transl Psychiatry. 2022; 12: 395. Published online 2022 Sep 20. doi: 10.1038/s41398-022-02143-1

PMCID:: PMC9489881

Abstract Article PDF–1.4M

Select item 899674516.

Dissecting the contribution of host genetics and the microbiome in complex behaviors

Shelly A. Buffington, Sean W. Dooling, Martina Sgritta, Cecilia Noecker, Oscar D. Murillo, Daniela F. Felice, Peter J. Turnbaugh, Mauro Costa-Mattioli

Cell. Author manuscript; available in PMC 2022 Apr 11.

Published in final edited form as: Cell. 2021 Apr 1; 184(7): 1740–1756.e16. Published online 2021 Mar 10. doi: 10.1016/j.cell.2021.02.009

PMCID:: PMC8996745

Abstract Article PDF–3.1M

Select item 894491517.

Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse

Katrina Y. Choe, Richard A. I. Bethlehem, Martin Safrin, Hongmei Dong, Elena Salman, Ying Li, Valery Grinevich, Peyman Golshani, Laura A. DeNardo, Olga Peñagarikano, Neil G. Harris, Daniel H. Geschwind

Neuron. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: Neuron. 2022 Mar 2; 110(5): 795–808.e6. Published online 2021 Dec 20. doi: 10.1016/j.neuron.2021.11.031

PMCID:: PMC8944915

Abstract Article PDF–2.3M

Select item 891766018.

Deep phenotyping reveals movement phenotypes in mouse neurodevelopmental models

Ugne Klibaite, Mikhail Kislin, Jessica L. Verpeut, Silke Bergeler, Xiaoting Sun, Joshua W. Shaevitz, Samuel S.-H. Wang

Mol Autism. 2022; 13: 12. Published online 2022 Mar 12. doi: 10.1186/s13229-022-00492-8

PMCID:: PMC8917660

Abstract Article PDF–7.4M

Select item 888790319.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 885854520.

Decreased in vivo glutamate/GABA ratio correlates with the social behavior deficit in a mouse model of autism spectrum disorder

Gaeun Park, Se Jin Jeon, In Ok Ko, Ji Hwan Park, Kyo Chul Lee, Min-Sik Kim, Chan Young Shin, Hyeonjin Kim, Yong-Seok Lee

Mol Brain. 2022; 15: 19. Published online 2022 Feb 19. doi: 10.1186/s13041-022-00904-z

PMCID:: PMC8858545

Abstract Article PDF–2.0M

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