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Select item 103078521.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95223413.

Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors

Daniel Cabello-Rivera, Patricia Ortega-Sáenz, Lin Gao, Ana M. Muñoz-Cabello, Victoria Bonilla-Henao, Paul T. Schumacker, José López-Barneo

Proc Natl Acad Sci U S A. 2022 Sep 27; 119(39): e2202178119. Published online 2022 Sep 19. doi: 10.1073/pnas.2202178119

PMCID:: PMC9522341

Abstract Article PDF–2.3M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73933515.

Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis

Yi Yao, Queping Liu, Indra Adrianto, Xiaojun Wu, James Glassbrook, Namir Khalasawi, Congcong Yin, Qijun Yi, Zheng Dong, Frederic Geissmann, Li Zhou, Qing-Sheng Mi

Nat Commun. 2020; 11: 3822. Published online 2020 Jul 30. doi: 10.1038/s41467-020-17630-6

PMCID:: PMC7393351

Abstract Article PDF–2.9M

Select item 64716136.

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Shuang Zhang, Samuel Weinberg, Matthew DeBerge, Anastasiia Gainullina, Matthew Schipma, Jason M. Kinchen, Issam Ben-Sahra, David R. Gius, Laurent Yvan-Charvet, Navdeep S. Chandel, Paul T. Schumacker, Edward B. Thorp

Cell Metab. Author manuscript; available in PMC 2020 Feb 5.

Published in final edited form as: Cell Metab. 2019 Feb 5; 29(2): 443–456.e5. Published online 2018 Dec 27. doi: 10.1016/j.cmet.2018.12.004

PMCID:: PMC6471613

Abstract Article PDF–1.2M

Select item 63455967.

Mitochondrial complex III is essential for regulatory T cell suppressive function

Samuel E. Weinberg, Benjamin D. Singer, Elizabeth M. Steinert, Carlos A. Martinez, Manan M. Mehta, Inmaculada Martínez-Reyes, Peng Gao, Kathryn A. Helmin, Hiam Abdala-Valencia, Laura A. Sena, Paul T. Schumacker, Laurence A. Turka, Navdeep S. Chandel

Nature. Author manuscript; available in PMC 2019 Jul 9.

Published in final edited form as: Nature. 2019 Jan; 565(7740): 495–499. Published online 2019 Jan 9. doi: 10.1038/s41586-018-0846-z

PMCID:: PMC6345596

Abstract Article PDF–4.4M

Select item 62441838.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 60697059.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin

Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5

PMCID:: PMC6069705

Abstract Article PDF–5.5M

Select item 579902310.

Chemical cross-linking mass spectrometry analysis of protein conformations and supercomplexes in heart tissue

Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Andrew Keller, Rong Tian, James E. Bruce

Cell Syst. Author manuscript; available in PMC 2019 Jan 24.

Published in final edited form as: Cell Syst. 2018 Jan 24; 6(1): 136–141.e5. Published online 2017 Nov 29. doi: 10.1016/j.cels.2017.10.017

PMCID:: PMC5799023

Abstract Article PDF–730K

Select item 579538811.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Abstract Article PDF–4.4M

Select item 577859612.

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria

Taru Hilander, Xiao-Long Zhou, Svetlana Konovalova, Fu-Ping Zhang, Liliya Euro, Dmitri Chilov, Matti Poutanen, Joseph Chihade, En-Duo Wang, Henna Tyynismaa

Nucleic Acids Res. 2018 Jan 25; 46(2): 849–860. Published online 2017 Dec 8. doi: 10.1093/nar/gkx1231

PMCID:: PMC5778596

Abstract Article PDF–10M

Select item 547476013.

The mitochondrial respiratory chain is essential for haematopoietic stem cell function

Elena Ansó, Samuel E. Weinberg, Lauren P. Diebold, Benjamin J. Thompson, Sébastien Malinge, Paul T. Schumacker, Xin Liu, Yuannyu Zhang, Zhen Shao, Mya Steadman, Kelly M. Marsh, Jian Xu, John D. Crispino, Navdeep S. Chandel

Nat Cell Biol. Author manuscript; available in PMC 2017 Nov 15.

Published in final edited form as: Nat Cell Biol. 2017 Jun; 19(6): 614–625. Published online 2017 May 15. doi: 10.1038/ncb3529

PMCID:: PMC5474760

Abstract Article PDF–2.8M

Select item 538122614.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 532103215.

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

Devin K. Schweppe, Juan D. Chavez, Chi Fung Lee, Arianne Caudal, Shane E. Kruse, Rudy Stuppard, David J. Marcinek, Gerald S. Shadel, Rong Tian, James E. Bruce

Proc Natl Acad Sci U S A. 2017 Feb 14; 114(7): 1732–1737. Published online 2017 Jan 27. doi: 10.1073/pnas.1617220114

PMCID:: PMC5321032

Abstract Article PDF–1.1M

Select item 425582016.

Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolism

Jérôme Lapointe, Bryan G. Hughes, Eve Bigras, Siegfried Hekimi

Physiol Rep. 2014 Nov; 2(11): e12214. Published online 2014 Nov 20. doi: 10.14814/phy2.12214

PMCID:: PMC4255820

Abstract Article PDF–3.2M

Select item 360359517.

Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation

Gregory B. Waypa, Jeremy D. Marks, Robert D. Guzy, Paul T. Mungai, Jacqueline M. Schriewer, Danijela Dokic, Molly K. Ball, Paul T. Schumacker

Am J Respir Crit Care Med. 2013 Feb 15; 187(4): 424–432. Published online 2013 Feb 15. doi: 10.1164/rccm.201207-1294OC

PMCID:: PMC3603595

Abstract Article PDF–1.2M

Select item 358274118.

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling

Laura A. Sena, Sha Li, Amit Jairaman, Murali Prakriya, Teresa Ezponda, David A. Hildeman, Chyung-Ru Wang, Paul T. Schumacker, Jonathan D. Licht, Harris Perlman, Paul J. Bryce, Navdeep S. Chandel

Immunity. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Immunity. 2013 Feb 21; 38(2): 225–236. Published online 2013 Feb 15. doi: 10.1016/j.immuni.2012.10.020

PMCID:: PMC3582741

Abstract Article PDF–2.6M

Select item 349051319.

A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions

Francisca Diaz, Sofia Garcia, Kyle R. Padgett, Carlos T. Moraes

Hum Mol Genet. 2012 Dec 1; 21(23): 5066–5077. Published online 2012 Aug 21. doi: 10.1093/hmg/dds350

PMCID:: PMC3490513

Abstract Article PDF–528K

Select item 325578220.

Cells Lacking Rieske Iron-Sulfur Protein Have a Reactive Oxygen Species-Associated Decrease in Respiratory Complexes I and IV

Francisca Diaz, José Antonio Enríquez, Carlos T. Moraes

Mol Cell Biol. 2012 Jan; 32(2): 415–429. doi: 10.1128/MCB.06051-11

PMCID:: PMC3255782

Abstract Article PDF–2.2M

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