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Select item 110631601.

Large-language models facilitate discovery of the molecular signatures regulating sleep and activity

Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang

Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w

PMCID:: PMC11063160

Abstract Article PDF–2.7M

Select item 109627592.

A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

Annabel Guichard, Shenzhao Lu, Oguz Kanca, Daniel Bressan, Yan Huang, Mengqi Ma, Sara Sanz Juste, Jonathan C. Andrews, Kristy L. Jay, Marketta Sneider, Ruth Schwartz, Mei-Chu Huang, Danqing Bei, Hongling Pan, Liwen Ma, Wen-Wen Lin, Ankush Auradkar, Pranjali Bhagwat, Soo Park, Kenneth H. Wan, Takashi Ohsako, Toshiyuki Takano-Shimizu, Susan E. Celniker, Michael F. Wangler, Shinya Yamamoto, Hugo J. Bellen, Ethan Bier

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112842. Published online 2023 Jul 20. doi: 10.1016/j.celrep.2023.112842

PMCID:: PMC10962759

Abstract Article PDF–3.0M

Select item 108477153.

Fourth Chromosome Resource Project: a comprehensive resource for genetic analysis in Drosophila that includes humanized stocks

Michael J Stinchfield, Brandon P Weasner, Bonnie M Weasner, David Zhitomersky, Justin P Kumar, Michael B O’Connor, Stuart J Newfeld

Genetics. 2024 Feb; 226(2): iyad201. Published online 2023 Nov 20. doi: 10.1093/genetics/iyad201

PMCID:: PMC10847715

Abstract Article PDF–1.2M

Select item 106655744.

Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster

Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang

Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555

PMCID:: PMC10665574

Abstract Article PDF–1.1M

Select item 98619075.

ATP13A2 Gene Silencing in Drosophila Affects Autophagic Degradation of A53T Mutant α-Synuclein

Nisha R. Dhanushkodi, Salema B. Abul Khair, Mustafa T. Ardah, M. Emdadul Haque

Int J Mol Sci. 2023 Jan; 24(2): 1775. Published online 2023 Jan 16. doi: 10.3390/ijms24021775

PMCID:: PMC9861907

Abstract Article PDF–2.9M

Select item 92396806.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 82704848.

Loss of UCHL1 rescues the defects related to Parkinson’s disease by suppressing glycolysis

Su Jin Ham, Daewon Lee, Wen Jun Xu, Eunjoo Cho, Sekyu Choi, Soohong Min, Sunghyouk Park, Jongkyeong Chung

Sci Adv. 2021 Jul; 7(28): eabg4574. Published online 2021 Jul 9. doi: 10.1126/sciadv.abg4574

PMCID:: PMC8270484

Abstract Article PDF–7.4M

Select item 79983169.

The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson’s Disease

Melissa Vos, Christine Klein

Cells. 2021 Mar; 10(3): 579. Published online 2021 Mar 6. doi: 10.3390/cells10030579

PMCID:: PMC7998316

Abstract Article PDF–1.7M

Select item 688105510.

SON protects nascent transcripts from unproductive degradation by counteracting DIP1

Mandy Li-Ian Tay, Jun Wei Pek

PLoS Genet. 2019 Nov; 15(11): e1008498. Published online 2019 Nov 15. doi: 10.1371/journal.pgen.1008498

PMCID:: PMC6881055

Abstract Article PDF–1.9M

Select item 631455211.

ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion

Ruoxi Wang, Jieqiong Tan, Tingting Chen, Hailong Han, Runyi Tian, Ya Tan, Yiming Wu, Jingyi Cui, Fang Chen, Jie Li, Lu Lv, Xinjie Guan, Shuai Shang, Jiahong Lu, Zhuohua Zhang

J Cell Biol. 2019 Jan 7; 218(1): 267–284. doi: 10.1083/jcb.201804165

PMCID:: PMC6314552

Abstract Article PDF–5.0M

Select item 591973212.

Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells

Stephanie E. Mohr, Kirstin Rudd, Yanhui Hu, Wei Roc Song, Quentin Gilly, Michael Buckner, Benjamin E. Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, Norbert Perrimon

G3 (Bethesda) 2018 Feb; 8(2): 631–641. Published online 2017 Dec 9. doi: 10.1534/g3.117.300447

PMCID:: PMC5919732

Abstract Article PDF–1.0M

Select item 570780513.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900214.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 549914515.

The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects

Amanda S. Lobell, Rachel R. Kaspari, Yazmin L. Serrano Negron, Susan T. Harbison

G3 (Bethesda) 2017 Jul; 7(7): 2391–2403. Published online 2017 May 26. doi: 10.1534/g3.117.042390

PMCID:: PMC5499145

Abstract Article PDF–1.7M

Select item 532559516.

RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides

Katharine C. Abruzzi, Abigail Zadina, Weifei Luo, Evelyn Wiyanto, Reazur Rahman, Fang Guo, Orie Shafer, Michael Rosbash

PLoS Genet. 2017 Feb; 13(2): e1006613. Published online 2017 Feb 9. doi: 10.1371/journal.pgen.1006613

PMCID:: PMC5325595

Abstract Article PDF–3.1M

Select item 457069717.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 452833018.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832919.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 445195020.

MicroRNA-Dependent Transcriptional Silencing of Transposable Elements in Drosophila Follicle Cells

Bruno Mugat, Abdou Akkouche, Vincent Serrano, Claudia Armenise, Blaise Li, Christine Brun, Tudor A. Fulga, David Van Vactor, Alain Pélisson, Séverine Chambeyron

PLoS Genet. 2015 May; 11(5): e1005194. Published online 2015 May 19. doi: 10.1371/journal.pgen.1005194

PMCID:: PMC4451950

Abstract Article PDF–3.5M

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