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Select item 105434631.

Activated Protein C, Protein S, and Tissue Factor Pathway Inhibitor Cooperate to Inhibit Thrombin Activation

Xian Li, Xiaohong Song, Dlovan F. D Mahmood, Martha M.S. Sim, Sara J. Bidarian, Jeremy P. Wood

Thromb Res. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Thromb Res. 2023 Oct; 230: 84–93. Published online 2023 Aug 23. doi: 10.1016/j.thromres.2023.08.012

PMCID:: PMC10543463

Abstract Article PDF–2.6M

Select item 102794692.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Sean A. Burnap, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Hashim Ali, Kaloyan Takov, Matthew Fish, Manu Shankar-Hari, Mauro Giacca, Michael H. Malim, Manuel Mayr

Mol Cell Proteomics. 2023 Aug; 22(8): 100600. Published online 2023 Jun 19. doi: 10.1016/j.mcpro.2023.100600

PMCID:: PMC10279469

Abstract Article PDF–3.2M

Select item 102077353.

Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood

Shuhei Miura, Zahra A. Habibabady, Franziska Pollok, Margaret Connolly, Shannon Pratts, Amy Dandro, Lori Sorrells, Kasinath Karavi, Carol Phelps, Will Eyestone, David Ayares, Lars Burdorf, Agnes Azimzadeh, Richard N. Pierson, III

Xenotransplantation. Author manuscript; available in PMC 2023 May 24.

Published in final edited form as: Xenotransplantation. 2022 Mar; 29(2): e12725. Published online 2022 Mar 2. doi: 10.1111/xen.12725

PMCID:: PMC10207735

Abstract Article PDF–2.0M

Select item 101199594.

Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation

Janina Wittig, Maria-Kyriaki Drekolia, Anastasia Kyselova, Fredy Delgado Lagos, Magdalena L. Bochenek, Jiong Hu, Katrin Schäfer, Ingrid Fleming, Sofia-Iris Bibli

Redox Biol. 2023 Jun; 62: 102694. Published online 2023 Apr 3. doi: 10.1016/j.redox.2023.102694

PMCID:: PMC10119959

Abstract Article PDF–3.6M

Select item 97725585.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 96613816.

Mutations of TFPI-binding exosites on factor VII cause bleeding phenotypes in factor VII deficiency

Karnsasin Seanoon, Panwajee Payongsri, Pornpun Vivithanaporn, Nongnuch Sirachainan, Ampaiwan Chuansumrit, Suradej Hongeng, Pansakorn Tanratana

Blood Adv. 2022 Nov 22; 6(22): 5887–5897. Published online 2022 Aug 19. doi: 10.1182/bloodadvances.2022007560

PMCID:: PMC9661381

Abstract Article PDF–1.3M

Select item 92316237.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 87489588.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 86856699.

Intersection of regulatory pathways controlling hemostasis and hemochorial placentation

Masanaga Muto, Damayanti Chakraborty, Kaela M. Varberg, Ayelen Moreno-Irusta, Khursheed Iqbal, Regan L. Scott, Ross P. McNally, Ruhul H. Choudhury, John D. Aplin, Hiroaki Okae, Takahiro Arima, Shoma Matsumoto, Masatsugu Ema, Alan E. Mast, Elin Grundberg, Michael J. Soares

Proc Natl Acad Sci U S A. 2021 Dec 14; 118(50): e2111267118. Published online 2021 Dec 7. doi: 10.1073/pnas.2111267118

PMCID:: PMC8685669

Abstract Article PDF–4.2M

Select item 862069610.

Single Nucleotide Polymorphisms from CSF2, FLT1, TFPI and TLR9 Genes Are Associated with Prelabor Rupture of Membranes

Wioletta Izabela Wujcicka, Marian Kacerovsky, Michał Krekora, Piotr Kaczmarek, Mariusz Grzesiak

Genes (Basel) 2021 Nov; 12(11): 1725. Published online 2021 Oct 28. doi: 10.3390/genes12111725

PMCID:: PMC8620696

Abstract Article PDF–785K

Select item 826974811.

A major reservoir for heparin-releasable TFPIα is extracellular matrix

Julie A. Peterson, Susan A. Maroney, Nicholas D. Martinez, Alan E. Mast

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Jun; 41(6): 1942–1955. Published online 2021 Apr 8. doi: 10.1161/ATVBAHA.120.315728

PMCID:: PMC8269748

Abstract Article PDF–2.0M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 784611213.

A rare coding mutation in the MAST2 gene causes venous thrombosis in a French family with unexplained thrombophilia: The Breizh MAST2 Arg89Gln variant

Pierre-Emmanuel Morange, Franck Peiretti, Lenaick Gourhant, Carole Proust, Omar Soukarieh, Anne-Sophie Pulcrano-Nicolas, Ganapathi-Varma Saripella, Luca Stefanucci, Romaric Lacroix, Manal Ibrahim-Kosta, Catherine A. Lemarié, Mattia Frontini, Marie-Christine Alessi, David-Alexandre Trégouët, Francis Couturaud

PLoS Genet. 2021 Jan; 17(1): e1009284. Published online 2021 Jan 19. doi: 10.1371/journal.pgen.1009284

PMCID:: PMC7846112

Abstract Article PDF–1.5M

Select item 783935414.

Elevated levels of tissue factor pathway inhibitor in patients with mild to moderate bleeding tendency

Dino Mehic, Alexander Tolios, Stefanie Hofer, Cihan Ay, Helmuth Haslacher, Judit Rejtö, Willem H. Ouwehand, Kate Downes, Matthias Haimel, Ingrid Pabinger, Johanna Gebhart

Blood Adv. 2021 Jan 26; 5(2): 391–398. Published online 2021 Jan 19. doi: 10.1182/bloodadvances.2020003464

PMCID:: PMC7839354

Abstract Article PDF–897K

Select item 752655115.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

Select item 670930516.

Association of TFPI polymorphisms rs8176592, rs10931292, and rs10153820 with venous thrombosis: A meta-analysis

Yunhong Zhang, Aimei Pang, Lin Zhao, Qiang Guo, Zhen Zhang, Xiaoxiao Zhu, Ran Wei, Xunqiang Yin, Bin Wang, Xia Li

Medicine (Baltimore) 2019 Mar; 98(12): e14978. Published online 2019 Mar 22. doi: 10.1097/MD.0000000000014978

PMCID:: PMC6709305

Abstract Article PDF–918K

Select item 652715417.

Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors

Dávid Szakács, Andrea Kocsis, Róbert Szász, Péter Gál, Gábor Pál

J Biol Chem. 2019 May 17; 294(20): 8227–8237. Published online 2019 Apr 5. doi: 10.1074/jbc.RA119.008315

PMCID:: PMC6527154

Abstract Article PDF–1.3M

Select item 588003118.

Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength

Stella Thomassen, Tom G. Mastenbroek, Frauke Swieringa, Kristien Winckers, Marion A.H. Feijge, Roy Schrijver, Judith M.E.M. Cosemans, Susan A. Maroney, Alan E. Mast, Tilman M. Hackeng, Johan W.M. Heemskerk

Thromb Haemost. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Thromb Haemost. 2018 Mar; 118(3): 502–513. Published online 2018 Feb 16. doi: 10.1055/s-0038-1627453

PMCID:: PMC5880031

Abstract Article PDF–1.0M

Select item 579460719.

Significant genetic association of a functional TFPI variant with circulating fibrinogen levels and coronary artery disease

Duraid Hamid Naji, Chengcheng Tan, Fabin Han, Yuanyuan Zhao, Junhan Wang, Dan Wang, Jingjing Fa, Sisi Li, Shanshan Chen, Qiuyun Chen, Chengqi Xu, Qing K. Wang

Mol Genet Genomics. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Mol Genet Genomics. 2018 Feb; 293(1): 119–128. Published online 2017 Sep 11. doi: 10.1007/s00438-017-1365-6

PMCID:: PMC5794607

Abstract Article PDF–414K

Select item 570911720.

Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma

Atanur Ersayin, Aline Thomas, Landry Seyve, Nicole Thielens, Mathieu Castellan, Raphaël Marlu, Benoît Polack, Marie-Claire Dagher

Haematologica. 2017 Dec; 102(12): e483–e485. doi: 10.3324/haematol.2017.174037

PMCID:: PMC5709117

Article PDF–862K

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