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Select item 112501451.

miR‐485‐3p targets SIRT1 in vascular smooth muscle cells mediating the occurrence of aortic dissection

Yuling Xie, Linfeng Xie, Zhihuang Qiu, Jian He, Fei Jiang, Meiling Cai, Yanjuan Lin, Liangwan Chen

J Cell Mol Med. 2024 Jul; 28(13): e18454. Published online 2024 Jul 15. doi: 10.1111/jcmm.18454

PMCID:: PMC11250145

Abstract Article PDF–17M

Select item 111782962.

Clock genes regulate skeletal muscle energy metabolism through NAMPT/NAD⁺/SIRT1 following heavy-load exercise

Yu Xia, Binyu Yao, Zeting Fu, Lunyu Li, Songlin Jin, Bo Qu, Ying Huang, Haili Ding

Am J Physiol Regul Integr Comp Physiol. 2023 Nov 1; 325(5): R490–R503. Published online 2023 Aug 7. doi: 10.1152/ajpregu.00261.2022

PMCID:: PMC11178296

Abstract Article

Select item 111740533.

Sirtuin1 (sirt1) regulates the glycolysis pathway and decreases cisplatin chemotherapeutic sensitivity to esophageal squamous cell carcinoma

Xuewen Yang, Shisen Li, Chunsheng Xu, Shushang Liu, Xiang Zhang, Bo Lian, Mengbin Li

Cancer Biol Ther. 2024; 25(1): 2365449. Published online 2024 Jun 12. doi: 10.1080/15384047.2024.2365449

PMCID:: PMC11174053

Abstract Article PDF–7.5M

Select item 111694834.

The mitochondrial protease ClpP is a druggable target that controls VSMC phenotype by a SIRT1-dependent mechanism

Felipe Paredes, Holly C. Williams, Xuesong Liu, Claire Holden, Bethany Bogan, Yu Wang, Kathryn M. Crotty, Samantha M. Yeligar, Alvaro A. Elorza, Zhiyong Lin, Amir Rezvan, Alejandra San Martin

Redox Biol. 2024 Jul; 73: 103203. Published online 2024 May 21. doi: 10.1016/j.redox.2024.103203

PMCID:: PMC11169483

Abstract Article PDF–7.3M

Select item 111599655.

Balance between SIRT1 and DBC1 expression is lost in breast cancer

Ji‐Youn Sung, Ranah Kim, Ja‐Eun Kim, Juhie Lee

Cancer Sci. 2010 Jul; 101(7): 1738–1744. Published online 2010 Mar 24. doi: 10.1111/j.1349-7006.2010.01573.x

PMCID:: PMC11159965

Abstract Article PDF–415K

Select item 111481846.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 110966457.

miRNA-142-3p aggravates hydrogen peroxide-induced human umbilical vein endothelial cell premature senescence by targeting SIRT1

Pengfei Tong, Jingke Zhang, Shuang Liu, Jiyang An, Gehan Jing, Laifeng Ma, Ruihua Wang, Zhengfeng Wang

Biosci Rep. 2024 May 29; 44(5): BSR20231511. Published online 2024 May 15. doi: 10.1042/BSR20231511

PMCID:: PMC11096645

Abstract Article PDF–3.9M

Select item 110503528.

Neutrophil Elastase Degrades Histone Deacetylases and Sirtuin 1 in Primary Human Monocyte Derived Macrophages

Shuo Zheng, Gamze B. Bulut, Apparao B. Kummarapurugu, Jonathan Ma, Judith A. Voynow

Int J Mol Sci. 2024 Apr; 25(8): 4265. Published online 2024 Apr 12. doi: 10.3390/ijms25084265

PMCID:: PMC11050352

Abstract Article PDF–3.7M

Select item 110112489.

Analysis of SIRT1 Gene SNPs and Clinical Characteristics in Medication-Related Osteonecrosis of the Jaw

Bence Bojtor, Mihaly Vaszilko, Richard Armos, Balint Tobias, Janos Podani, Szofia Szentpeteri, Bernadett Balla, Balazs Lengyel, Henriett Piko, Anett Illes, Andras Kiss, Zsuzsanna Putz, Istvan Takacs, Janos P. Kosa, Peter Lakatos

Int J Mol Sci. 2024 Apr; 25(7): 3646. Published online 2024 Mar 25. doi: 10.3390/ijms25073646

PMCID:: PMC11011248

Abstract Article PDF–1.5M

Select item 1100841810.

Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis

Xing-Nian Zhou, Quan Zhang, Hong Peng, Yu-Jie Qin, Yu-Hong Liu, Lu Wang, Ming-Liang Cheng, Xin-Hua Luo, Hong Li

World J Gastroenterol. 2024 Mar 21; 30(11): 1588–1608. Published online 2024 Mar 21. doi: 10.3748/wjg.v30.i11.1588

PMCID:: PMC11008418

Abstract Article PDF–18M

Select item 1100677411.

A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers

Anna Barbato, Fabiola Piscopo, Massimiliano Salati, Carla Pollastro, Lorenzo Evangelista, Luigi Ferrante, Davide Limongello, Simona Brillante, Antonella Iuliano, Luca Reggiani-Bonetti, Maria Salatiello, Antonino Iaccarino, Pasquale Pisapia, Umberto Malapelle, Giancarlo Troncone, Alessia Indrieri, Massimo Dominici, Brunella Franco, Pietro Carotenuto

Clin Exp Med. 2024; 24(1): 74. Published online 2024 Apr 10. doi: 10.1007/s10238-024-01332-0

PMCID:: PMC11006774

Abstract Article PDF–7.2M

Select item 1099190312.

miR-34a induces immunosuppression in colorectal carcinoma through modulating a SIRT1/NF-κB/B7-H3/TNF-α axis

Fanyi Meng, Man Yang, Yinshuang Chen, Weichang Chen, Weipeng Wang

Cancer Immunol Immunother. 2021 Aug; 70(8): 2247–2259. Published online 2021 Jan 25. doi: 10.1007/s00262-021-02862-2

PMCID:: PMC10991903

Abstract Article PDF–4.0M

Select item 1098509513.

SIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity

Ji An Kang, Yoon Jung Kim, Kyu Yun Jang, Hye Won Moon, Haeseung Lee, Seonjeong Lee, Hyun Kyu Song, Sang Woo Cho, Yoon Sun Yoo, Hye Gyeong Han, Min-Ju Kim, Myoung Ja Chung, Cheol Yong Choi, Cheolju Lee, Chaeuk Chung, Gang Min Hur, You-Sun Kim, Young Joo Jeon

Exp Mol Med. 2024 Mar; 56(3): 656–673. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01194-2

PMCID:: PMC10985095

Abstract Article PDF–3.2M

Select item 1096565714.

Effect of SIRT1 gene single-nucleotide polymorphisms on susceptibility to type 1 diabetes in a Han Chinese population

J. Li, Y. Yang, Y. Xia, S. Luo, J. Lin, Y. Xiao, X. Li, G. Huang, L. Yang, Z. Xie, Z. Zhou

J Endocrinol Invest. 2024; 47(4): 819–826. Published online 2023 Sep 11. doi: 10.1007/s40618-023-02190-5

PMCID:: PMC10965657

Abstract Article PDF–618K

Select item 1093326715.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 1089679116.

Neuronal Stem Cells from Late-Onset Alzheimer Patients Show Altered Regulation of Sirtuin 1 Depending on Apolipoprotein E Indicating Disturbed Stem Cell Plasticity

Matthias Jung, Juliane-Susanne Jung, Jenny Pfeifer, Carla Hartmann, Toni Ehrhardt, Chaudhry Luqman Abid, Jenny Kintzel, Anne Puls, Anne Navarrete Santos, Thomas Hollemann, Dagmar Riemann, Dan Rujescu

Mol Neurobiol. 2024; 61(3): 1562–1579. Published online 2023 Sep 20. doi: 10.1007/s12035-023-03633-z