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Select item 112591591.

A fibronectin gradient remodels mixed-phase mesoderm

Min Zhu, Bin Gu, Evan C. Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M. Yung, Xin Chen, Kaiwen Zhang, Elizabeth K. Woolaver, Mikaela R. Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun, Sevan Hopyan

Sci Adv. 2024 Jul 19; 10(29): eadl6366. Published online 2024 Jul 19. doi: 10.1126/sciadv.adl6366

PMCID:: PMC11259159

Abstract Article PDF–6.7M

Select item 110941892.

Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

Yaechan Song, Heeju Na, Seung Eon Lee, You Min Kim, Jihyun Moon, Tae Wook Nam, Yul Ji, Young Jin, Jae Hyung Park, Seok Chan Cho, Jaehoon Lee, Daehee Hwang, Sang-Jun Ha, Hyun Woo Park, Jae Bum Kim, Han-Woong Lee

Nat Commun. 2024; 15: 4052. Published online 2024 May 14. doi: 10.1038/s41467-024-48179-3

Correction in:: Nat Commun. 2024; 15: 5623.

PMCID:: PMC11094189

Abstract Article PDF–8.2M

Select item 110773753.

TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction

Hyo Kyeong Kim, Hana Jeong, Mi Gyeong Jeong, Hee Yeon Won, Gibbeum Lee, Soo Han Bae, Miso Nam, Sung Hoon Lee, Geum-Sook Hwang, Eun Sook Hwang

Int J Biol Sci. 2024; 20(7): 2592–2606. Published online 2024 Apr 22. doi: 10.7150/ijbs.88897

PMCID:: PMC11077375

Abstract Article PDF–9.3M

Select item 108102234.

The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromuscular junctions in skeletal muscle fibers

Lea Gessler, Danyil Huraskin, Yongzhi Jian, Nane Eiber, Zhaoyong Hu, Tomasz J Prószyński, Said Hashemolhosseini

Nucleic Acids Res. 2024 Jan 25; 52(2): 600–624. Published online 2023 Dec 4. doi: 10.1093/nar/gkad1124

PMCID:: PMC10810223

Abstract Article PDF–3.7M

Select item 107897915.

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury

Ari Kwon, Na Young Lee, Jae-Hyun Yu, Myeung Gi Choi, Jeongwoo Park, Ja Hyun Koo

Cell Death Dis. 2024 Jan; 15(1): 51. Published online 2024 Jan 15. doi: 10.1038/s41419-024-06448-5

PMCID:: PMC10789791

Abstract Article PDF–6.2M

Select item 107514436.

TAZ stimulates exercise‐induced muscle satellite cell activation via Pard3–p38 MAPK–TAZ signalling axis

Kyung Min Kim, Gi Don Yoo, Woong Heo, Ho Taek Oh, Jeekeon Park, Somin Shin, Youjin Do, Mi Gyeong Jeong, Eun Sook Hwang, Jeong‐Ho Hong

J Cachexia Sarcopenia Muscle. 2023 Dec; 14(6): 2733–2746. Published online 2023 Nov 3. doi: 10.1002/jcsm.13348

PMCID:: PMC10751443

Abstract Article PDF–2.6M

Select item 107017687.

TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment

Anat Gershoni, Ori Hassin, Nishanth Belugali Nataraj, Sivan Baruch, Adi Avioz‐Seligman, Anna Chiara Pirona, Liat Fellus‐Alyagor, Tomer Meir Salame, Saptaparna Mukherjee, Giuseppe Mallel, Yosef Yarden, Yael Aylon, Moshe Oren

Mol Oncol. 2023 Dec; 17(12): 2675–2693. Published online 2023 Oct 16. doi: 10.1002/1878-0261.13525

PMCID:: PMC10701768

Abstract Article PDF–2.0M

Select item 106217518.

Inducible tricolor reporter mouse for parallel imaging of lysosomes, mitochondria, and microtubules

Vera Hutchison, Anne Lynch, Andrés Mauricio Gutierrez-Gamez, Jichao Chen

J Cell Biol. 2024 Jan 1; 223(1): e202305086. Published online 2023 Nov 2. doi: 10.1083/jcb.202305086

PMCID:: PMC10621751

Abstract Article PDF–6.3M

Select item 106031129.

Genetic interactions between polycystin-1 and Wwtr1 in osteoblasts define a novel mechanosensing mechanism regulating bone formation in mice

Zhousheng Xiao, Li Cao, Micholas Dean Smith, Hanxuan Li, Wei Li, Jeremy C. Smith, Leigh Darryl Quarles

Bone Res. 2023; 11: 57. Published online 2023 Oct 26. doi: 10.1038/s41413-023-00295-4

PMCID:: PMC10603112

Abstract Article PDF–2.4M

Select item 1054421110.

Vascular smooth muscle–specific YAP/TAZ deletion triggers aneurysm development in mouse aorta

Marycarmen Arévalo Martínez, Olivia Ritsvall, Joakim Armstrong Bastrup, Selvi Celik, Gabriel Jakobsson, Fatima Daoud, Christopher Winqvist, Anders Aspberg, Catarina Rippe, Lars Maegdefessel, Alexandru Schiopu, Thomas A. Jepps, Johan Holmberg, Karl Swärd, Sebastian Albinsson

JCI Insight. 2023 Sep 8; 8(17): e170845. Published online 2023 Sep 8. doi: 10.1172/jci.insight.170845

PMCID:: PMC10544211

Abstract Article PDF–27M

Select item 1050438311.

Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries

Melody Devos, Joana Dias Nunes, Nathalie Donfack Jiatsa, Isabelle Demeestere

Sci Rep. 2023; 13: 15346. Published online 2023 Sep 15. doi: 10.1038/s41598-023-41954-0

PMCID:: PMC10504383

Abstract Article PDF–3.0M

Select item 1041243412.

Loss of TAZ after YAP deletion severely impairs foregut development and worsens cholestatic hepatocellular injury

Adelya Gabdulkhakova, Yekaterina Krutsenko, Junjie Zhu, Silvia Liu, Minakshi Poddar, Sucha Singh, Xiaochao Ma, Kari Nejak-Bowen, Satdarshan P.S. Monga, Laura M. Molina

Hepatol Commun. 2023 Sep; 7(9): e0220. Published online 2023 Aug 9. doi: 10.1097/HC9.0000000000000220

PMCID:: PMC10412434

Abstract Article PDF–1.7M

Select item 1040428613.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 1030574114.

A YAP/TAZ-CD54 axis is required for CXCR2⁻CD44⁻ tumor-specific neutrophils to suppress gastric cancer

Pingping Nie, Weihong Zhang, Yan Meng, Moubin Lin, Fenghua Guo, Hui Zhang, Zhenzhu Tong, Meng Wang, Fan Chen, Liwei An, Yang Tang, Yi Han, Ruixian Yu, Wenjia Wang, Yuanzhi Xu, Linxin Wei, Zhaocai Zhou, Shi Jiao

Protein Cell. 2023 Jul; 14(7): 515–533. Published online 2022 Oct 26. doi: 10.1093/procel/pwac045

PMCID:: PMC10305741

Abstract Article PDF–7.4M

Select item 1029014315.

The role of mechano-regulated YAP/TAZ in erectile dysfunction

Mintao Ji, Dongsheng Chen, Yinyin Shu, Shuai Dong, Zhisen Zhang, Haimeng Zheng, Xiaoni Jin, Lijun Zheng, Yang Liu, Yifei Zheng, Wensheng Zhang, Shiyou Wang, Guangming Zhou, Bingyan Li, Baohua Ji, Yong Yang, Yongde Xu, Lei Chang

Nat Commun. 2023; 14: 3758. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39009-z

PMCID:: PMC10290143

Abstract Article PDF–7.2M

Select item 1026673616.

Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

Caiqi Cheng, Qian Cong, Yuchen Liu, Yizhong Hu, Guoyan Liang, Kevin Marc Manquiquis Dioneda, Yingzi Yang

Sci Adv. 2023 Jun; 9(24): eadf6927. Published online 2023 Jun 14. doi: 10.1126/sciadv.adf6927

PMCID:: PMC10266736

Abstract Article PDF–2.4M

Select item 1019788917.

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling

Zhenhua Feng, Siyue Tao, Zhaobo Huang, Bingjie Zheng, Xiangxi Kong, Yufeng Xiang, Qibin Zhang, Haixin Song, Zhikun Xu, Xiaoan Wei, Fengdong Zhao, Jian Chen

Int J Biol Sci. 2023; 19(8): 2319–2332. Published online 2023 Apr 24. doi: 10.7150/ijbs.82152

PMCID:: PMC10197889

Abstract Article PDF–7.7M

Select item 1013232118.

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy

Brian C. Leonard, Sangwan Park, Soohyun Kim, Laura J. Young, Iman Jalilian, Krista Cosert, Xunzhi Zhang, Jessica M. Skeie, Hanna Shevalye, Nayeli Echeverria, Vanessa Rozo, Xin Gong, Chao Xing, Christopher J. Murphy, Mark A. Greiner, V. Vinod Mootha, Vijay Krishna Raghunathan, Sara M. Thomasy

Invest Ophthalmol Vis Sci. 2023 Apr; 64(4): 22. Published online 2023 Apr 19. doi: 10.1167/iovs.64.4.22

PMCID:: PMC10132321

Abstract Article PDF–1.5M

Select item 1011449819.

Regenerative reprogramming of the intestinal stem cell state via Hippo signaling suppresses metastatic colorectal cancer

Priscilla Cheung, Jordi Xiol, Michael T. Dill, Wei-Chien Yuan, Riccardo Panero, Jatin Roper, Fernando G. Osorio, Dejan Maglic, Qi Li, Basanta Gurung, Raffaele A. Calogero, Ömer H. Yilmaz, Junhao Mao, Fernando D. Camargo

Cell Stem Cell. Author manuscript; available in PMC 2023 Apr 19.

Published in final edited form as: Cell Stem Cell. 2020 Oct 1; 27(4): 590–604.e9. Published online 2020 Jul 29. doi: 10.1016/j.stem.2020.07.003

PMCID:: PMC10114498

Abstract Article PDF–2.4M

Select item 1008277820.

Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2

Rui Li, Jingchen Shao, Young-June Jin, Haruya Kawase, Yu Ting Ong, Kerstin Troidl, Qi Quan, Lei Wang, Remy Bonnavion, Astrid Wietelmann, Francoise Helmbacher, Michael Potente, Johannes Graumann, Nina Wettschureck, Stefan Offermanns

Nat Commun. 2023; 14: 1980. Published online 2023 Apr 8. doi: 10.1038/s41467-023-37671-x