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Select item 111905731.

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development

Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga

Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722

PMCID:: PMC11190573

Abstract Article

Select item 111611232.

Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis

Archana Kumari, Nicole E. Franks, Libo Li, Gabrielle Audu, Sarah Liskowicz, John D. Johnson, Charlotte M. Mistretta, Benjamin L. Allen

PLoS One. 2024; 19(6): e0294835. Published online 2024 Jun 7. doi: 10.1371/journal.pone.0294835

PMCID:: PMC11161123

Abstract Article PDF–7.0M

Select item 110980993.

A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex

Xiaoyi G. Liang, Kendy Hoang, Brandon L. Meyerink, Pratiksha Kc, Kitt Paraiso, Li Wang, Ian R. Jones, Yue Zhang, Sol Katzman, Thomas S. Finn, Jeremiah Tsyporin, Fangyuan Qu, Zhaoxu Chen, Axel Visel, Arnold Kriegstein, Yin Shen, Louis-Jan Pilaz, Bin Chen

Proc Natl Acad Sci U S A. 2024 May 14; 121(20): e2321711121. Published online 2024 May 7. doi: 10.1073/pnas.2321711121

PMCID:: PMC11098099

Abstract Article PDF–16M

Select item 110146574.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109726195.

Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis

Boang Han, Yu Wang, Shen Yue, Yun-hao Zhang, Lun Kuang, Bin-bin Gao, Yue Wang, Ziyu Zhang, Xiaohong Pu, Xin-fa Wang, Chi-chung Hui, Ting-ting Yu, Chen Liu, Steven Y. Cheng

JCI Insight. 2024 Mar 22; 9(6): e176044. Published online 2024 Feb 15. doi: 10.1172/jci.insight.176044

PMCID:: PMC10972619

Abstract Article PDF–3.1M

Select item 107626776.

BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period

Zhenmeiyu Li, Guoping Liu, Lin Yang, Mengge Sun, Zhuangzhi Zhang, Zhejun Xu, Yanjing Gao, Xin Jiang, Zihao Su, Xiaosu Li, Zhengang Yang

Protein Cell. 2024 Jan; 15(1): 21–35. Published online 2023 Jun 10. doi: 10.1093/procel/pwad036

PMCID:: PMC10762677

Abstract Article PDF–55M

Select item 106627147.

Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis

Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay

PLoS Genet. 2023 Nov; 19(11): e1011028. Published online 2023 Nov 9. doi: 10.1371/journal.pgen.1011028

PMCID:: PMC10662714

Abstract Article PDF–5.4M

Select item 106517358.

A Neanderthal/Denisovan GLI3 variant contributes to anatomical variations in mice

Ako Agata, Satoshi Ohtsuka, Ryota Noji, Hitoshi Gotoh, Katsuhiko Ono, Tadashi Nomura

Front Cell Dev Biol. 2023; 11: 1247361. Published online 2023 Nov 2. doi: 10.3389/fcell.2023.1247361

PMCID:: PMC10651735

Abstract Article PDF–2.6M

Select item 104819479.

Disrupting Hedgehog signaling in melanocytes by SUFU knockout leads to ocular melanocytosis and anterior segment malformation

Weizhuo Wang, Feiyang Li, Jing Wang, Zuimeng Liu, Meiyu Tian, Zhenhang Wang, Huirong Li, Jia Qu, Yu Chen, Ling Hou

Dis Model Mech. 2023 Aug 1; 16(8): dmm050210. Published online 2023 Aug 29. doi: 10.1242/dmm.050210

PMCID:: PMC10481947

Abstract Article

Select item 1038711010.

Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development

Jiyoung Lee, Yeonjoo Kim, Paris Ataliotis, Hyung-Goo Kim, Dae-Won Kim, Dorothy C. Bennett, Nigel A. Brown, Lawrence C. Layman, Soo-Hyun Kim

Sci Rep. 2023; 13: 12309. Published online 2023 Jul 29. doi: 10.1038/s41598-023-38017-9

PMCID:: PMC10387110

Abstract Article PDF–11M

Select item 1020371011.

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos

Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng

Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245

PMCID:: PMC10203710

Abstract Article PDF–4.6M

Select item 1007300912.

Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse

Sarah Escuin, Saba Rose Raza-Knight, Dawn Savery, Carles Gaston-Massuet, Gabriel L. Galea, Nicholas D. E. Greene, Andrew J. Copp

Dis Model Mech. 2023 Mar 1; 16(3): dmm049858. Published online 2023 Mar 14. doi: 10.1242/dmm.049858

PMCID:: PMC10073009

Abstract Article

Select item 970969313.

Sonic Hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice

Jianjian Zhu, Rashmi Patel, Anna Trofka, Brian D. Harfe, Susan Mackem

Dev Cell. Author manuscript; available in PMC 2023 Sep 12.

Published in final edited form as: Dev Cell. 2022 Sep 12; 57(17): 2048–2062.e4. Published online 2022 Aug 16. doi: 10.1016/j.devcel.2022.07.016

PMCID:: PMC9709693

Abstract Article PDF–2.6M

Select item 966948614.

Tissue-specific requirement of sodium channel and clathrin linker 1 (Sclt1) for ciliogenesis during limb development

Hankyu Lee, Kyeong-Hye Moon, Jieun Song, Suyeon Je, Jinwoong Bok, Hyuk Wan Ko

Front Cell Dev Biol. 2022; 10: 1058895. Published online 2022 Nov 3. doi: 10.3389/fcell.2022.1058895

PMCID:: PMC9669486

Abstract Article PDF–2.8M

Select item 961805215.

Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation

Tianli Qin, Chin Chung Ho, Boshi Wang, Chi-Chung Hui, Mai Har Sham

Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2206571119. Published online 2022 Oct 17. doi: 10.1073/pnas.2206571119

PMCID:: PMC9618052

Abstract Article PDF–1.9M

Select item 948191716.

The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis

Shuang-Feng Zhang, Shang-Kun Dai, Hong-Zhen Du, Hui Wang, Xing-Guo Li, Yi Tang, Chang-Mei Liu

Stem Cell Reports. 2022 Sep 13; 17(9): 2064–2080. Published online 2022 Aug 4. doi: 10.1016/j.stemcr.2022.07.004

PMCID:: PMC9481917

Abstract Article PDF–9.5M

Select item 935266717.

Ca²⁺ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling

Ke-Yan Yang, Song Zhao, Haiping Feng, Jiaqi Shen, Yuwei Chen, Si-Tong Wang, Si-Jia Wang, Yu-Xin Zhang, Yun Wang, Caixia Guo, Hongmei Liu, Tie-Shan Tang

Cell Death Dis. 2022 Aug; 13(8): 674. Published online 2022 Aug 4. doi: 10.1038/s41419-022-05131-x

PMCID:: PMC9352667

Abstract Article PDF–6.9M

Select item 934870718.

A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum, Sherine F. Elsawa

Oncotarget. 2022; 13: 944–959. Published online 2022 Aug 3. doi: 10.18632/oncotarget.28261