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Select item 109878711.

NKX2-1 gene is targeted by H19 lncRNA and is found to be overexpressed in benign nodular goiter tissues

Seyed-Morteza Javadirad

Braz J Otorhinolaryngol. 2024 Jul-Aug; 90(4): 101409. Published online 2024 Feb 28. doi: 10.1016/j.bjorl.2024.101409

PMCID:: PMC10987871

Abstract Article PDF–2.3M

Select item 101476152.

Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer

Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Shauni L. Geeraerts, Tom Venken, Kalina Timcheva, David Nittner, Jelle Verbeeck, Jonathan Royaert, Marion Gijbels, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, Kim R. Kampen

Br J Cancer. 2023 May 11; 128(10): 1862–1878. Published online 2023 Mar 17. doi: 10.1038/s41416-023-02216-y

PMCID:: PMC10147615

Abstract Article PDF–4.2M

Select item 99106493.

Exploring the values, preferences, and information needs of patients with NKX2-1-related disorders: A qualitative study protocol

Carmen Martín-Gómez, Juan Dario Ortigoza-Escobar, Laia Nou-Fontanet, Juan M. Molina-Linde, Anne-Catherine Bachoud-Lévi, Juliane Léger, Juan Antonio Blasco-Amaro, NKX2-1-Related Disorders Guideline Working Group

PLoS One. 2023; 18(2): e0281573. Published online 2023 Feb 9. doi: 10.1371/journal.pone.0281573

PMCID:: PMC9910649

Abstract Article PDF–508K

Select item 98950544.

Relationship between brain metastasis and thyroid transcription factor 1

Engin Kut, Serkan Menekşe

Sci Rep. 2023; 13: 1945. Published online 2023 Feb 2. doi: 10.1038/s41598-023-29236-1

PMCID:: PMC9895054

Abstract Article PDF–963K

Select item 97570945.

Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer

Ranran Kong, Ayushi S. Patel, Takashi Sato, Feng Jiang, Seungyeul Yoo, Li Bao, Abhilasha Sinha, Yang Tian, Maya Fridrikh, Shuhui Liu, Jie Feng, Xijing He, Jiantao Jiang, Yuefeng Ma, Karina Grullon, Dawei Yang, Charles A. Powell, Mary Beth Beasley, Jun Zhu, Eric L. Snyder, Shaomin Li, Hideo Watanabe

Am J Respir Crit Care Med. 2022 Dec 15; 206(12): 1480–1494. Published online 2022 Jul 18. doi: 10.1164/rccm.202110-2358OC

PMCID:: PMC9757094

Abstract Article PDF–3.5M

Select item 96760966.

Optimized thyroid transcription factor-1 core promoter-driven microRNA-7 expression effectively inhibits the growth of human non-small-cell lung cancer cells

Shipeng CHEN, Lian GUAN, Xu ZHAO, Jing YANG, Longqing CHEN, Mengmeng GUO, Juanjuan ZHAO, Chao CHEN, Ya ZHOU, Yong HAN, Lin XU

J Zhejiang Univ Sci B. 2022 Nov 15; 23(11): 915–930. doi: 10.1631/jzus.B2200116

PMCID:: PMC9676096

Abstract Article PDF–4.0M

Select item 95403457.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 93785478.

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma

Grace Orstad, Gabriela Fort, Timothy J Parnell, Alex Jones, Chris Stubben, Brian Lohman, Katherine L. Gillis, Walter Orellana, Rushmeen Tariq, Olaf Klingbeil, Klaus Kaestner, Christopher R. Vakoc, Benjamin T. Spike, Eric L. Snyder

Dev Cell. Author manuscript; available in PMC 2023 Aug 8.

Published in final edited form as: Dev Cell. 2022 Aug 8; 57(15): 1866–1882.e10. Published online 2022 Jul 13. doi: 10.1016/j.devcel.2022.06.017

PMCID:: PMC9378547

Abstract Article PDF–3.2M

Select item 89605669.

Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations

Steffi Thust, Liana Veneziano, Michael H. Parkinson, Kailash P. Bhatia, Elide Mantuano, Cristina Gonzalez-Robles, Indran Davagnanam, Paola Giunti

Neurogenetics. 2022; 23(2): 91–102. Published online 2022 Jan 25. doi: 10.1007/s10048-021-00680-3

PMCID:: PMC8960566

Abstract Article PDF–1.1M

Select item 882662010.

SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1–Negative Lung Adenocarcinomas

Ichidai Tanaka, Delphine Dayde, Mei Chee Tai, Haruki Mori, Luisa M Solis, Satyendra C Tripathi, Johannes F Fahrmann, Nese Unver, Gargy Parhy, Rekha Jain, Edwin R Parra, Yoshiko Murakami, Clemente Aguilar-Bonavides, Barbara Mino, Muge Celiktas, Dilsher Dhillon, Julian Phillip Casabar, Masahiro Nakatochi, Francesco Stingo, Veera Baladandayuthapani, Hong Wang, Hiroyuki Katayama, Jennifer B Dennison, Philip L Lorenzi, Kim-Anh Do, Junya Fujimoto, Carmen Behrens, Edwin J Ostrin, Jaime Rodriguez-Canales, Tetsunari Hase, Takayuki Fukui, Taisuke Kajino, Seiichi Kato, Yasushi Yatabe, Waki Hosoda, Koji Kawaguchi, Kohei Yokoi, Toyofumi F Chen-Yoshikawa, Yoshinori Hasegawa, Adi F Gazdar, Ignacio I Wistuba, Samir Hanash, Ayumu Taguchi

J Natl Cancer Inst. 2022 Feb; 114(2): 290–301. Published online 2021 Sep 15. doi: 10.1093/jnci/djab183

PMCID:: PMC8826620

Abstract Article PDF–2.5M

Select item 857525511.

NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells

Yuko Ito, Fumihiko Furuya, Katsumi Taki, Hideaki Suzuki, Hiroki Shimura

PLoS One. 2021; 16(11): e0259558. Published online 2021 Nov 8. doi: 10.1371/journal.pone.0259558

PMCID:: PMC8575255

Abstract Article PDF–2.2M

Select item 825191512.

NKX2.1 run‐on mutation associated to familial brain–lung–thyroid syndrome

Elena Cavaliere, Anna Jolanda Gortan, Nadia Passon, Dora Fabbro, Dario Marin, Miryam Carecchio, Federica Baldan, Sara Carmela Credendino, Rosa Gallo, Paola Cogo, Giuseppe Damante, Gabriella De Vita

Clin Genet. 2021 Jul; 100(1): 114–116. Published online 2021 Mar 29. doi: 10.1111/cge.13961

PMCID:: PMC8251915

Abstract Article PDF–642K

Select item 813291213.

TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection

Aya Miyagawa-Hayashino, Satoru Okada, Naoko Takeda-Miyata, Yasutoshi Takashima, Tadaaki Yamada, Yoshizumi Takemura, Junji Uchino, Masayoshi Inoue, Koichi Takayama, Eiichi Konishi

Appl Immunohistochem Mol Morphol. 2021 Apr; 29(4): 313–320. Published online 2020 Oct 7. doi: 10.1097/PAI.0000000000000875

PMCID:: PMC8132912

Abstract Article PDF–493K

Select item 812374414.

Deletion of conserved non‐coding sequences downstream from NKX2‐1: A novel disease‐causing mechanism for benign hereditary chorea

Jun Liao, Keith A. Coffman, Joseph Locker, Quasar S. Padiath, Bruce Nmezi, Robyn A. Filipink, Jie Hu, Malini Sathanoori, Suneeta Madan‐Khetarpal, Marianne McGuire, Allison Schreiber, Rocio Moran, Neil Friedman, Lori Hoffner, Aleksandar Rajkovic, Svetlana A. Yatsenko, Urvashi Surti

Mol Genet Genomic Med. 2021 Apr; 9(4): e1647. Published online 2021 Mar 5. doi: 10.1002/mgg3.1647

PMCID:: PMC8123744

Abstract Article PDF–1.0M

Select item 811529415.

CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung

William D. Stuart, Iris M. Fink-Baldauf, Koichi Tomoshige, Minzhe Guo, Yutaka Maeda

Commun Biol. 2021; 4: 568. Published online 2021 May 12. doi: 10.1038/s42003-021-02083-4

PMCID:: PMC8115294

Abstract Article PDF–3.4M

Select item 804593216.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 760485717.

The E3 ubiquitin ligase HECW1 targets thyroid transcription factor 1 (TTF1/NKX2.1) for its degradation in the ubiquitin-proteasome system

Jia Liu, Su Dong, Lian Li, Heather Wang, Jing Zhao, Yutong Zhao

Cell Signal. Author manuscript; available in PMC 2020 Nov 2.

Published in final edited form as: Cell Signal. 2019 Jun; 58: 91–98. Published online 2019 Mar 5. doi: 10.1016/j.cellsig.2019.03.005

PMCID:: PMC7604857

Abstract Article PDF–738K

Select item 740643718.

TTF-1与小细胞肺癌一线化疗敏感性及预后的相关性分析

王冰睿, 丰暖, 石新艳, 綦琦, 迟晓蕊, 宋婷婷, 李红梅

Zhongguo Fei Ai Za Zhi. 2020 Jul 20; 23(7): 547–553. Chinese. doi: 10.3779/j.issn.1009-3419.2020.101.27

PMCID:: PMC7406437

Abstract Article PDF–1.2M

Select item 729308219.

Reciprocal expression of trefoil factor‐1 and thyroid transcription factor‐1 in lung adenocarcinomas

Daisuke Matsubara, Taichiro Yoshimoto, Manabu Soda, Yusuke Amano, Atsushi Kihara, Toko Funaki, Takeshi Ito, Yuji Sakuma, Tomoki Shibano, Shunsuke Endo, Koichi Hagiwara, Shumpei Ishikawa, Masashi Fukayama, Yoshinori Murakami, Hiroyuki Mano, Toshiro Niki

Cancer Sci. 2020 Jun; 111(6): 2183–2195. Published online 2020 Apr 30. doi: 10.1111/cas.14403

PMCID:: PMC7293082

Abstract Article PDF–1.3M

Select item 704513220.

Spectrum of somatic EGFR, KRAS, BRAF, PTEN mutations and TTF-1 expression in Brazilian lung cancer patients

JULIANA G. CARNEIRO, PATRICIA G. COUTO, LUCIANA BASTOS-RODRIGUES, MARIA APARECIDA C. BICALHO, PAULA V. VIDIGAL, ALYNE VILHENA, NILSON F. AMARAL, ALLEN E. BALE, EITAN FRIEDMAN, LUIZ DE MARCO

Genet Res (Camb) 2014; 96: e002. Published online 2014 Mar 5. doi: 10.1017/S0016672314000032

PMCID:: PMC7045132

Abstract Article PDF–159K

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