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Items: 1 to 20 of 290

1.
Serine 39 in the GTP‐binding domain of Drp1 is involved in shaping mitochondrial morphology
Marvi Ghani, Bernadett Szabó, Mahmoud Alkhatibe, Hailemariam Amsalu, Peleg Zohar, Eszter Anna Janka, János András Mótyán, Krisztina Tar
FEBS Open Bio. 2024 Jul; 14(7): 1147–1165. Published online 2024 May 17. doi: 10.1002/2211-5463.13820
PMCID:
PMC11216946
AbstractArticlePDF–14M
2.
GTPBP8 modulates mitochondrial fission through a Drp1-dependent process
Xiumei He, Liang Wang, Hoi Ying Tsang, Xiaonan Liu, Xiaofeng Yang, Shiming Pu, Ziqi Guo, Cheng Yang, Qiong Wu, Zuping Zhou, Xiaobo Cen, Hongxia Zhao
J Cell Sci. 2024 Apr 15; 137(8): jcs261612. Published online 2024 Apr 30. doi: 10.1242/jcs.261612
PMCID:
PMC11112121
AbstractArticle
3.
MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1
Yuqiong Chen, Su Li, Bo Guan, Xiaopei Yan, Chao Huang, Yingqiang Du, Fan Yang, Nannan Zhang, Yafei Li, Jian Lu, Jiankang Wang, Jun Zhang, Zhangwei Chen, Chao Chen, Xiangqing Kong
Cardiovasc Diabetol. 2024; 23: 164. Published online 2024 May 9. doi: 10.1186/s12933-024-02254-7
PMCID:
PMC11084109
AbstractArticlePDF–8.9M
4.
Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
Parash Prasad, Sampurna Ghosh, Sib Sankar Roy
Cell Mol Life Sci. 2021 May; 78(10): 4821–4845. Published online 2021 Apr 24. doi: 10.1007/s00018-021-03818-6
PMCID:
PMC11073067
AbstractArticlePDF–9.0M
5.
A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
Rebecca Z. Fan, Carolina Sportelli, Yanhao Lai, Said S. Salehe, Jennifer R. Pinnell, Harry J. Brown, Jason R. Richardson, Shouqing Luo, Kim Tieu
Mol Neurodegener. 2024; 19: 26. Published online 2024 Mar 19. doi: 10.1186/s13024-024-00708-w
PMCID:
PMC10953112
AbstractArticlePDF–12M
6.
Mitochondrial Raf1 Regulates Glutamine Catabolism
Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari
Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297
PMCID:
PMC10942467
AbstractArticlePDF–6.5M
7.
Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin
Ao Liu, Anna L. Hatch, Henry N. Higgs
Mol Biol Cell. 2024 Feb 1; 35(2): ar16. Published online 2024 Jan 12. doi: 10.1091/mbc.E23-11-0427
PMCID:
PMC10881151
AbstractArticlePDF–5.4M
8.
Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of PD-1 inhibitors in treating lung cancer
Jietao Ma, Jun Song, Xiaofang Yi, Shuling Zhang, Li Sun, Letian Huang, Chengbo Han
Cancer Immunol Immunother. 2024 Feb; 73(2): 40. Published online 2024 Feb 10. doi: 10.1007/s00262-023-03582-5
PMCID:
PMC10858821
AbstractArticlePDF–3.6M
9.
Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission
Kelsey A. Nolden, Megan C. Harwig, R. Blake Hill
J Biol Chem. 2023 Dec; 299(12): 105380. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105380
PMCID:
PMC10694664
AbstractArticlePDF–4.1M
10.
DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs
Gabriella L. Robertson, Stellan Riffle, Mira Patel, Caroline Bodnya, Andrea Marshall, Heather K. Beasley, Edgar Garza-Lopez, Jianqiang Shao, Zer Vue, Antentor Hinton, Jr, Maria S. Stoll, Sholto de Wet, Rensu P. Theart, Ram Prosad Chakrabarty, Ben Loos, Navdeep S. Chandel, Jason A. Mears, Vivian Gama
J Cell Sci. 2023 Feb 1; 136(3): jcs260370. Published online 2023 Feb 10. doi: 10.1242/jcs.260370
PMCID:
PMC10657212
AbstractArticle
11.
A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission
Ugochukwu K. Ihenacho, Rafael Toro, Rana H. Mansour, R. Blake Hill
J Biol Chem. 2023 Nov; 299(11): 105303. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105303
PMCID:
PMC10641528
AbstractArticlePDF–7.7M
12.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
13.
Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration
Wencan Ke, Bingjin Wang, Zhiwei Liao, Yu Song, Gaocai Li, Liang Ma, Kun Wang, Shuai Li, Wenbin Hua, Cao Yang
J Transl Med. 2023; 21: 711. Published online 2023 Oct 10. doi: 10.1186/s12967-023-04590-w
PMCID:
PMC10563269
AbstractArticlePDF–1.8M
14.
An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity
Stephanie M. Almeida, Sofiia Ivantsiv, Rieko Niibori, Wade H. Dunham, Brooke A. Green, Liang Zhao, Anne-Claude Gingras, Sabine P. Cordes
Dis Model Mech. 2023 Aug 1; 16(8): dmm049762. Published online 2023 Aug 17. doi: 10.1242/dmm.049762
PMCID:
PMC10445738
AbstractArticle
15.
YY2‐DRP1 Axis Regulates Mitochondrial Fission and Determines Cancer Stem Cell Asymmetric Division
Mankun Wei, Uli Nurjanah, Juan Li, Xinxin Luo, Rendy Hosea, Yanjun Li, Jianting Zeng, Wei Duan, Guanbin Song, Makoto Miyagishi, Vivi Kasim, Shourong Wu
Adv Sci (Weinh) 2023 Aug; 10(23): 2207349. Published online 2023 Jun 9. doi: 10.1002/advs.202207349
PMCID:
PMC10427375
AbstractArticlePDF–8.2M
16.
The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases
Pierce Colpman, Asish Dasgupta, Stephen L. Archer
Cells. 2023 Jul; 12(14): 1897. Published online 2023 Jul 20. doi: 10.3390/cells12141897
PMCID:
PMC10378656
AbstractArticlePDF–4.9M
17.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
18.
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
Dane T. Sessions, Kee-Beom Kim, Jennifer A. Kashatus, Nikolas Churchill, Kwon-Sik Park, Marty W. Mayo, Hiromi Sesaki, David F. Kashatus
Cell Rep. Author manuscript; available in PMC 2023 Jun 14.
Published in final edited form as: Cell Rep. 2022 Dec 13; 41(11): 111818. doi: 10.1016/j.celrep.2022.111818
PMCID:
PMC10265649
AbstractArticlePDF–2.8M
19.
Disease-associated mutations in Drp1 have fundamentally different effects on the mitochondrial fission machinery
Brianna L Bauer, Kristy Rochon, Jasmine C Liu, Rajesh Ramachandran, Jason A Mears
Hum Mol Genet. 2023 Jun 15; 32(12): 1975–1987. Published online 2023 Feb 16. doi: 10.1093/hmg/ddad029
PMCID:
PMC10244223
AbstractArticlePDF–2.7M
20.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M

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