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Select item 105211371.

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman

Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1

PMCID:: PMC10521137

Abstract Article PDF–4.0M

Select item 102922102.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 92098113.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 86827944.

VID22 counteracts G-quadruplex-induced genome instability

Elena Galati, Maria C Bosio, Daniele Novarina, Matteo Chiara, Giulia M Bernini, Alessandro M Mozzarelli, Maria L García-Rubio, Belén Gómez-González, Andrés Aguilera, Thomas Carzaniga, Marco Todisco, Tommaso Bellini, Giulia M Nava, Gianmaria Frigè, Sarah Sertic, David S Horner, Anastasia Baryshnikova, Caterina Manzari, Anna M D’Erchia, Graziano Pesole, Grant W Brown, Marco Muzi-Falconi, Federico Lazzaro

Nucleic Acids Res. 2021 Dec 16; 49(22): 12785–12804. Published online 2021 Dec 6. doi: 10.1093/nar/gkab1156

PMCID:: PMC8682794

Abstract Article PDF–8.0M

Select item 65727715.

Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins

Peter Shyu, Jr., Benjamin S. H. Ng, Nurulain Ho, Ruijie Chaw, Yi Ling Seah, Charlie Marvalim, Guillaume Thibault

Sci Rep. 2019; 9: 8637. Published online 2019 Jun 14. doi: 10.1038/s41598-019-45020-6

PMCID:: PMC6572771

Abstract Article PDF–4.7M

Select item 64221016.

The natural anticancer agent cantharidin alters GPI-anchored protein sorting by targeting Cdc1-mediated remodeling in endoplasmic reticulum

Pushpendra Kumar Sahu, Raghuvir Singh Tomar

J Biol Chem. 2019 Mar 15; 294(11): 3837–3852. Published online 2019 Jan 18. doi: 10.1074/jbc.RA118.003890

PMCID:: PMC6422101

Abstract Article PDF–4.3M

Select item 63471707.

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation

Fabio Pereira, Mandy Rettel, Frank Stein, Mikhail M. Savitski, Ian Collinson, Karin Römisch

PLoS One. 2019; 14(1): e0211180. Published online 2019 Jan 25. doi: 10.1371/journal.pone.0211180

PMCID:: PMC6347170

Abstract Article PDF–16M

Select item 62162778.

A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export

Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, María E Pérez‐Martínez, Luis M Soares, Bernhard Dichtl, Stephen Buratowski, José E Pérez‐Ortín, Susana Rodríguez‐Navarro

EMBO Rep. 2018 Nov; 19(11): e45992. Published online 2018 Sep 24. doi: 10.15252/embr.201845992

PMCID:: PMC6216277

Abstract Article PDF–1.7M

Select item 62157139.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 592252810.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

Select item 571674111.

A systematic assessment of chemical, genetic, and epigenetic factors influencing the activity of anticancer drug KP1019 (FFC14A)

Upendarrao Golla, Swati Swagatika, Sakshi Chauhan, Raghuvir Singh Tomar

Oncotarget. 2017 Nov 17; 8(58): 98426–98454. Published online 2017 Sep 30. doi: 10.18632/oncotarget.21416

PMCID:: PMC5716741

Abstract Article PDF–11M

Select item 568948012.

Exploring Quantitative Yeast Phenomics with Single Cell Analysis of DNA Damage Foci

Erin B. Styles, Karen J. Founk, Lee A. Zamparo, Tina L. Sing, Dogus Altintas, Cyril Ribeyre, Virginie Ribaud, Jacques Rougemont, David Mayhew, Michael Costanzo, Matej Usaj, Adrian J. Verster, Elizabeth N. Koch, Daniele Novarina, Marco Graf, Brian Luke, Marco Muzi-Falconi, Chad L. Myers, Robi David Mitra, David Shore, Grant W. Brown, Zhaolei Zhang, Charles Boone, Brenda J. Andrews

Cell Syst. Author manuscript; available in PMC 2017 Nov 16.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 264–277.e10. Published online 2016 Sep 8. doi: 10.1016/j.cels.2016.08.008

PMCID:: PMC5689480

Abstract Article PDF–2.9M

Select item 566188513.

A global interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Oct 30.

Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420

PMCID:: PMC5661885

Abstract Article PDF–2.6M

Select item 560025414.

The Genetic Landscape of a Cell

Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone

Science. Author manuscript; available in PMC 2017 Sep 15.

Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823

PMCID:: PMC5600254

Abstract Article PDF–2.4M

Select item 559294515.

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark

G3 (Bethesda) 2017 Sep; 7(9): 3203–3215. Published online 2017 Jul 28. doi: 10.1534/g3.117.300089

PMCID:: PMC5592945

Abstract Article PDF–1.7M

Select item 548454416.

The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability

Tobias Wilms, Erwin Swinnen, Elja Eskes, Laura Dolz-Edo, Alice Uwineza, Ruben Van Essche, Joëlle Rosseels, Piotr Zabrocki, Elisabetta Cameroni, Vanessa Franssens, Claudio De Virgilio, Gertien J. Smits, Joris Winderickx

PLoS Genet. 2017 Jun; 13(6): e1006835. Published online 2017 Jun 12. doi: 10.1371/journal.pgen.1006835

PMCID:: PMC5484544

Abstract Article PDF–14M

Select item 524764317.

Loss of Cardiolipin Leads to Perturbation of Acetyl-CoA Synthesis

Vaishnavi Raja, Amit S. Joshi, Guiling Li, Krishna Rao Maddipati, Miriam L. Greenberg

J Biol Chem. 2017 Jan 20; 292(3): 1092–1102. Published online 2016 Dec 9. doi: 10.1074/jbc.M116.753624

PMCID:: PMC5247643

Abstract Article PDF–1.3M

Select item 520434818.

A novel translational control mechanism involving RNA structures within coding sequences

Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez

Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116

Correction in:: Genome Res. 2017 Apr; 27(4): 663.

PMCID:: PMC5204348

Abstract Article PDF–1.3M

Select item 505508319.

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Michael Mülleder, Enrica Calvani, Mohammad Tauqeer Alam, Richard Kangda Wang, Florian Eckerstorfer, Aleksej Zelezniak, Markus Ralser

Cell. 2016 Oct 6; 167(2): 553–565.e12. doi: 10.1016/j.cell.2016.09.007

PMCID:: PMC5055083

Abstract Article PDF–3.9M

Select item 496298120.

Chemogenetic E-MAP in Saccharomyces cerevisiae for Identification of Membrane Transporters Operating Lipid Flip Flop

Hector M. Vazquez, Christine Vionnet, Carole Roubaty, Shamroop k. Mallela, Roger Schneiter, Andreas Conzelmann

PLoS Genet. 2016 Jul; 12(7): e1006160. Published online 2016 Jul 27. doi: 10.1371/journal.pgen.1006160

PMCID:: PMC4962981

Abstract Article PDF–7.8M

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