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Select item 103491001.

Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis

Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver

Nat Commun. 2023; 14: 4129. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39672-2

PMCID:: PMC10349100

Abstract Article PDF–7.7M

Select item 102536672.

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer

Luis Puelles, Matias Hidalgo-Sánchez

Int J Mol Sci. 2023 Jun; 24(11): 9769. Published online 2023 Jun 5. doi: 10.3390/ijms24119769

PMCID:: PMC10253667

Abstract Article PDF–6.8M

Select item 100209793.

Chd5 Regulates the Transcription Factor Six3 to Promote Neuronal Differentiation

Padmina Shrestha, Anbalagan Jaganathan, Dhananjay Huilgol, Carlos Ballon, Yon Hwangbo, Alea A Mills

Stem Cells. 2023 Mar; 41(3): 242–251. Published online 2023 Jan 13. doi: 10.1093/stmcls/sxad002

PMCID:: PMC10020979

Abstract Article PDF–7.3M

Select item 98517464.

Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man

Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper

Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192

PMCID:: PMC9851746

Abstract Article PDF–3.5M

Select item 95347725.

Embryo model completes gastrulation to neurulation and organogenesis

Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz

Nature. 2022; 610(7930): 143–153. Published online 2022 Aug 25. doi: 10.1038/s41586-022-05246-3

PMCID:: PMC9534772

Abstract Article PDF–29M

Select item 94451696.

The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity

Zicong Shang, Lin Yang, Ziwu Wang, Yu Tian, Yanjing Gao, Zihao Su, Rongliang Guo, Weiwei Li, Guoping Liu, Xiaosu Li, Zhengang Yang, Zhenmeiyu Li, Zhuangzhi Zhang

Front Cell Dev Biol. 2022; 10: 948331. Published online 2022 Aug 23. doi: 10.3389/fcell.2022.948331

PMCID:: PMC9445169

Abstract Article PDF–9.7M

Select item 91970327.

Aberrant induction of p19^Arf-mediated cellular senescence contributes to neurodevelopmental defects

Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M. Keyes

PLoS Biol. 2022 Jun; 20(6): e3001664. Published online 2022 Jun 14. doi: 10.1371/journal.pbio.3001664

PMCID:: PMC9197032

Abstract Article PDF–3.1M

Select item 89342858.

Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice

Shanna N. Lavalle, Teresa Chou, Jacqueline Hernandez, Nay Chi P. Naing, Michelle Y. He, Karen J. Tonsfeldt, Pamela L. Mellon

Mol Cell Endocrinol. Author manuscript; available in PMC 2023 Apr 15.

Published in final edited form as: Mol Cell Endocrinol. 2022 Apr 15; 546: 111577. Published online 2022 Feb 2. doi: 10.1016/j.mce.2022.111577

PMCID:: PMC8934285

Abstract Article PDF–2.0M

Select item 89188089.

Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum

Zihao Su, Ziwu Wang, Susan Lindtner, Lin Yang, Zicong Shang, Yu Tian, Rongliang Guo, Yan You, Wenhao Zhou, John L. Rubenstein, Zhengang Yang, Zhuangzhi Zhang

Development. 2022 Feb 15; 149(4): dev200035. Published online 2022 Feb 23. doi: 10.1242/dev.200035

PMCID:: PMC8918808

Abstract Article

Select item 881055610.

Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved metabolic function, and dwarfism in male mice

Jason D. Meadows, Joseph A. Breuer, Shanna N. Lavalle, Michael R. Hirschenberger, Meera M. Patel, Duong Nguyen, Alyssa Kim, Jessica Cassin, Michael R. Gorman, David K. Welsh, Pamela L. Mellon, Hanne M. Hoffmann

Mol Metab. 2022 Mar; 57: 101431. Published online 2021 Dec 31. doi: 10.1016/j.molmet.2021.101431

PMCID:: PMC8810556

Abstract Article PDF–3.6M

Select item 880618611.

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

Hui Yu, Marcelo Rubinstein, Malcolm J Low

eLife. 2022; 11: e72883. Published online 2022 Jan 19. doi: 10.7554/eLife.72883

PMCID:: PMC8806186

Abstract Article PDF–26M

Select item 880618312.

Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors

Colin J Dinsmore, Philippe Soriano

eLife. 2022; 11: e75106. Published online 2022 Jan 19. doi: 10.7554/eLife.75106

PMCID:: PMC8806183

Abstract Article PDF–9.5M

Select item 874531913.

SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus

Arthur H. Cheng, Samuel W. Fung, Sara Hegazi, Osama Hasan Mustafa Hasan Abdalla, Hai-Ying Mary Cheng

Int J Mol Sci. 2022 Jan; 23(1): 229. Published online 2021 Dec 26. doi: 10.3390/ijms23010229

PMCID:: PMC8745319

Abstract Article PDF–4.2M

Select item 858387714.

Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1^−/− Mice

Jeyoung Bang, Minguk Han, Tack-Jin Yoo, Lu Qiao, Jisu Jung, Jiwoon Na, Bradley A. Carlson, Vadim N. Gladyshev, Dolph L. Hatfield, Jin-Hong Kim, Lark Kyun Kim, Byeong Jae Lee

Int J Mol Sci. 2021 Nov; 22(21): 11647. Published online 2021 Oct 28. doi: 10.3390/ijms222111647

PMCID:: PMC8583877

Abstract Article PDF–6.2M

Select item 857761815.

The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice

Hanne M. Hoffmann, Jason D. Meadows, Joseph A. Breuer, Alexandra M. Yaw, Duong Nguyen, Karen J. Tonsfeldt, Austin Y. Chin, Brooke M. Devries, Crystal Trang, Haley J. Oosterhouse, Jessica Sora Lee, Jeffrey W. Doser, Michael R. Gorman, David K. Welsh, Pamela L. Mellon

J Neurosci Res. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: J Neurosci Res. 2021 Oct; 99(10): 2625–2645. Published online 2021 Jul 2. doi: 10.1002/jnr.24864

PMCID:: PMC8577618

Abstract Article PDF–1.7M

Select item 827577716.

Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons

Xiaolei Song, Haotian Chen, Zicong Shang, Heng Du, Zhenmeiyu Li, Yan Wen, Guoping Liu, Dashi Qi, Yan You, Zhengang Yang, Zhuangzhi Zhang, Zhejun Xu

Neurosci Bull. 2021 Jul; 37(7): 985–998. Published online 2021 May 20. doi: 10.1007/s12264-021-00698-5

PMCID:: PMC8275777

Abstract Article PDF–14M

Select item 816749817.

Optic vesicle morphogenesis requires primary cilia

Luciano Fiore, Nozomu Takata, Sandra Acosta, Wanshu Ma, Tanushree Pandit, Michael Oxendine, Guillermo Oliver

Dev Biol. Author manuscript; available in PMC 2021 Jun 15.

Published in final edited form as: Dev Biol. 2020 Jun 15; 462(2): 119–128. Published online 2020 Mar 10. doi: 10.1016/j.ydbio.2020.02.016

PMCID:: PMC8167498

Abstract Article PDF–2.2M

Select item 799995218.

Meis homeobox genes control progenitor competence in the retina

Naoko Dupacova, Barbora Antosova, Jan Paces, Zbynek Kozmik

Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12): e2013136118. Published online 2021 Mar 15. doi: 10.1073/pnas.2013136118

PMCID:: PMC7999952

Abstract Article PDF–3.1M

Select item 795505519.

Transcriptional profiling reveals the transcription factor networks regulating the survival of striatal neurons

Lin Yang, Zihao Su, Ziwu Wang, Zhenmeiyu Li, Zicong Shang, Heng Du, Guoping Liu, Dashi Qi, Zhengang Yang, Zhejun Xu, Zhuangzhi Zhang

Cell Death Dis. 2021 Mar; 12(3): 262. Published online 2021 Mar 12. doi: 10.1038/s41419-021-03552-8

PMCID:: PMC7955055

Abstract Article PDF–4.9M

Select item 791038420.

Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala

Elena Garcia-Calero, Lara López-González, Margaret Martínez-de-la-Torre, Chen-Ming Fan, Luis Puelles

Brain Struct Funct. 2021; 226(2): 519–562. Published online 2021 Jan 25. doi: 10.1007/s00429-020-02197-1

PMCID:: PMC7910384

Abstract Article PDF–11M

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