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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 102297432.

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN

Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su

Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w

PMCID:: PMC10229743

Abstract Article PDF–2.9M

Select item 96101793.

ATP-Binding Cassette Transporter Family C Protein 10 Participates in the Synthesis and Efflux of Hexosylceramides in Liver Cells

Jahangir Iqbal, Meghan T. Walsh, M. Mahmood Hussain

Nutrients. 2022 Oct; 14(20): 4401. Published online 2022 Oct 20. doi: 10.3390/nu14204401

PMCID:: PMC9610179

Abstract Article PDF–3.1M

Select item 92626144.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 91902335.

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier

Raymond K. Hau, Robert R. Klein, Stephen H. Wright, Nathan J. Cherrington

Drug Metab Dispos. 2022 Jun; 50(6): 770–780. Published online 2022 Jun. doi: 10.1124/dmd.121.000748

PMCID:: PMC9190233

Abstract Article PDF–2.8M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80177207.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 64255808.

Genetic variation in the ATP binding cassette transporter ABCC10 is associated with neutropenia for docetaxel in Japanese lung cancer patients cohort

Kazuki Sone, Tetsuya Oguri, Takehiro Uemura, Akira Takeuchi, Satoshi Fukuda, Osamu Takakuwa, Ken Maeno, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Hirotsugu Ohkubo, Masaya Takemura, Yutaka Ito, Akio Niimi

BMC Cancer. 2019; 19: 246. Published online 2019 Mar 19. doi: 10.1186/s12885-019-5438-2

PMCID:: PMC6425580

Abstract Article PDF–821K

Select item 56306009.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 535242311.

FOXM1 evokes 5-fluorouracil resistance in colorectal cancer depending on ABCC10

Tao Xie, Jian Geng, Ye Wang, Liya Wang, Mengxi Huang, Jing Chen, Kai Zhang, Lijun Xue, Xiaobei Liu, Xiaobei Mao, Yanan Chen, Qian Wang, Tingting Dai, Lili Ren, Hongju Yu, Rui Wang, Longbang Chen, Cheng Chen, Xiaoyuan Chu

Oncotarget. 2017 Jan 31; 8(5): 8574–8589. Published online 2016 Dec 29. doi: 10.18632/oncotarget.14351

PMCID:: PMC5352423

Abstract Article PDF–33M

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 413449313.

Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment response

N Domanitskaya, J Wangari-Talbot, J Jacobs, E Peiffer, Y Mahdaviyeh, C Paulose, E Malofeeva, K Foster, K Q Cai, Y Zhou, B Egleston, E Hopper-Borge

Br J Cancer. 2014 Aug 12; 111(4): 696–707. Published online 2014 Jun 17. doi: 10.1038/bjc.2014.326

PMCID:: PMC4134493

Abstract Article PDF–4.2M

Select item 395443914.

Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10-Mediated Paclitaxel Resistance: A Preclinical Study

Rishil J. Kathawala, Kamlesh Sodani, Kang Chen, Atish Patel, Alaa H. Abuznait, Nagaraju Anreddy, Yue-Li Sun, Amal Kaddoumi, Charles R. Ashby, Jr., Zhe-Sheng Chen

Mol Cancer Ther. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Mol Cancer Ther. 2014 Mar; 13(3): 714–723. Published online 2014 Jan 15. doi: 10.1158/1535-7163.MCT-13-0743

PMCID:: PMC3954439

Abstract Article PDF–909K

Select item 360570015.

Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS

Neill J. Liptrott, Sudeep Pushpakom, Christoph Wyen, Gerd Fätkenheuer, Christian Hoffmann, Stefan Mauss, Heribert Knechten, Norbert H. Brockmeyer, Elizabeth Hopper-Borge, Marco Siccardi, David J. Back, Saye H. Khoo, Munir Pirmohamed, Andrew Owen

Pharmacogenet Genomics. Author manuscript; available in PMC 2013 Mar 22.

Published in final edited form as: Pharmacogenet Genomics. 2012 Jan; 22(1): 10–19. doi: 10.1097/FPC.0b013e32834dd82e

PMCID:: PMC3605700

Abstract Article PDF–793K

Select item 352572616.

Modulation of the ATPase and transport activities of broad-acting multidrug resistance factor ABCC10 (MRP7)

Ekaterina V. Malofeeva, Natalya Domanitskaya, Mariya Gudima, Elizabeth A. Hopper-Borge

Cancer Res. Author manuscript; available in PMC 2013 Dec 15.

Published in final edited form as: Cancer Res. 2012 Dec 15; 72(24): 6457–6467. Published online 2012 Oct 19. doi: 10.1158/0008-5472.CAN-12-1340

PMCID:: PMC3525726

Abstract Article PDF–2.6M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310503618.

Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction

Sudeep P. Pushpakom, Neill J. Liptrott, Sonia Rodríguez-Nóvoa, Pablo Labarga, Vincent Soriano, Marta Albalater, Elizabeth Hopper-Borge, Stefano Bonora, Giovanni Di Perri, David J. Back, Saye Khoo, Munir Pirmohamed, Andrew Owen

J Infect Dis. 2011 Jul 1; 204(1): 145–153. doi: 10.1093/infdis/jir215

PMCID:: PMC3105036

Abstract Article PDF–308K

Select item 309684819.

Contribution of Abcc10 (Mrp7) to in vivo paclitaxel resistance as assessed in Abcc10^−/− mice

Elizabeth A. Hopper-Borge, Timothy Churchill, Chelsy Paulose, Emmanuelle Nicolas, Joely D. Jacobs, Olivia Ngo, Yehong Kuang, Alex Grinberg, Heiner Westphal, Zhe-Sheng Chen, Andres J. Klein-Szanto, Martin G. Belinsky, Gary D. Kruh

Cancer Res. Author manuscript; available in PMC 2012 May 15.

Published in final edited form as: Cancer Res. 2011 May 15; 71(10): 3649–3657. doi: 10.1158/0008-5472.CAN-10-3623

PMCID:: PMC3096848

Abstract Article PDF–2.4M

Select item 295326020.

Lapatinib and erlotinib are potent reversal agents for MRP7(ABCC10)-mediated multidrug resistance

Ye-Hong Kuang, Tong Shen, Xiang Chen, Kamlesh Sodani, Elizabeth Hopper-Borge, Amit Kumar Tiwari, Jeferson W K K Lee, Li-Wu Fu, Zhe-Sheng Chen

Biochem Pharmacol. Author manuscript; available in PMC 2010 Oct 12.

Published in final edited form as: Biochem Pharmacol. 2010 Jan 15; 79(2): 154–161. Published online 2009 Aug 29. doi: 10.1016/j.bcp.2009.08.021

PMCID:: PMC2953260

Abstract Article PDF–1.5M

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