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Items: 1 to 20 of 105

1.
Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways
Yan Zhang, Huiwen Chen, Jinjin Wu, Abigail McVicar, Yilin Chen, Jiacan Su, Yi-Ping Li, Wei Chen
Int J Biol Sci. 2024; 20(6): 1965–1977. Published online 2024 Mar 11. doi: 10.7150/ijbs.90250
PMCID:
PMC11008268
AbstractArticlePDF–16M
2.
Core binding factor subunit β plays diverse and essential roles in the male germline
Mustika Rahmawati, Kassie M. Stadler, Blanca Lopez-Biladeau, Tia M. Hoisington, Nathan C. Law
Front Cell Dev Biol. 2023; 11: 1284184. Published online 2023 Nov 2. doi: 10.3389/fcell.2023.1284184
PMCID:
PMC10653448
AbstractArticlePDF–5.1M
3.
TRIB2 safeguards naive T cell homeostasis during aging
Wenqiang Cao, Ines Sturmlechner, Huimin Zhang, Jun Jin, Bin Hu, Rohit R. Jadhav, Fengqin Fang, Cornelia M. Weyand, Jörg J. Goronzy
Cell Rep. Author manuscript; available in PMC 2023 Apr 20.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112195. Published online 2023 Mar 6. doi: 10.1016/j.celrep.2023.112195
PMCID:
PMC10118747
AbstractArticlePDF–3.0M
4.
Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
Navdeep Malik, Young-Im Kim, Hualong Yan, Yu-Chou Tseng, Wendy du Bois, Gamze Ayaz, Andy D. Tran, Laura Vera-Ramirez, Howard Yang, Aleksandra M. Michalowski, Michael Kruhlak, Maxwell Lee, Kent W. Hunter, Jing Huang
Cancer Res. Author manuscript; available in PMC 2023 Oct 14.
Published in final edited form as: Cancer Res. 2023 Apr 14; 83(8): 1280–1298. doi: 10.1158/0008-5472.CAN-22-2525
PMCID:
PMC10106426
AbstractArticlePDF–1.4M
5.
Different Requirements of CBFB and RUNX2 in Skeletal Development among Calvaria, Limbs, Vertebrae and Ribs
Qing Jiang, Xin Qin, Kenichi Nagano, Hisato Komori, Yuki Matsuo, Ichiro Taniuchi, Kosei Ito, Toshihisa Komori
Int J Mol Sci. 2022 Nov; 23(21): 13299. Published online 2022 Oct 31. doi: 10.3390/ijms232113299
PMCID:
PMC9657020
AbstractArticlePDF–17M
6.
Multi-omics reveals mitochondrial metabolism proteins susceptible for drug discovery in AML
Mika Caplan, Karli J. Wittorf, Kasidy K. Weber, Samantha A. Swenson, Tyler J. Gilbreath, R. Willow Hynes-Smith, Catalina Amador, R. Katherine Hyde, Shannon M. Buckley
Leukemia. 2022; 36(5): 1296–1305. Published online 2022 Feb 17. doi: 10.1038/s41375-022-01518-z
PMCID:
PMC9061297
AbstractArticlePDF–3.2M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
The p53/miR-145a Axis Promotes Cellular Senescence and Inhibits Osteogenic Differentiation by Targeting Cbfb in Mesenchymal Stem Cells
Chao Xia, Tianyuan Jiang, Yonghui Wang, Xiaoting Chen, Yan Hu, Yanhong Gao
Front Endocrinol (Lausanne) 2020; 11: 609186. Published online 2021 Jan 11. doi: 10.3389/fendo.2020.609186
PMCID:
PMC7829338
AbstractArticlePDF–5.8M
9.
RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development
Tao Zhen, Yaqiang Cao, Gang Ren, Ling Zhao, R. Katherine Hyde, Guadalupe Lopez, Dechun Feng, Lemlem Alemu, Keji Zhao, P. Paul Liu
Blood. 2020 Nov 19; 136(21): 2373–2385. Prepublished online 2020 Sep 14. doi: 10.1182/blood.2020007747
PMCID:
PMC7685208
AbstractArticle
10.
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation
Jingmei Hsu, Hsuan-Ting Huang, Chung-Tsai Lee, Avik Choudhuri, Nicola K. Wilson, Brian J. Abraham, Victoria Moignard, Iwo Kucinski, Shuqian Yu, R. Katherine Hyde, Joanna Tober, Xiongwei Cai, Yan Li, Yalin Guo, Song Yang, Michael Superdock, Eirini Trompouki, Fernando J. Calero-Nieto, Alireza Ghamari, Jing Jiang, Peng Gao, Long Gao, Vy Nguyen, Anne L. Robertson, Ellen M. Durand, Katie L. Kathrein, Iannis Aifantis, Scott A. Gerber, Wei Tong, Kai Tan, Alan B. Cantor, Yi Zhou, P. Paul Liu, Richard A. Young, Berthold Göttgens, Nancy A. Speck, Leonard I. Zon
Proc Natl Acad Sci U S A. 2020 Sep 22; 117(38): 23626–23635. Published online 2020 Sep 3. doi: 10.1073/pnas.2003228117
Correction in:
Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2114827118.
PMCID:
PMC7519295
AbstractArticlePDF–3.1M
11.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
12.
Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice
Kyung-Eun Lim, Na-Rae Park, Xiangguo Che, Min-Su Han, Jae-Hwan Jeong, Shin-Yoon Kim, Clara Yongjoo Park, Haruhiko Akiyama, Jung-Eun Kim, Hyun-Mo Ryoo, Janet L. Stein, Jane B. Lian, Gary S. Stein, Je-Yong Choi
J Bone Miner Res. Author manuscript; available in PMC 2020 Jul 15.
Published in final edited form as: J Bone Miner Res. 2015 Apr; 30(4): 715–722. doi: 10.1002/jbmr.2397
Correction in:
J Bone Miner Res. 2015 Oct; 30(10): 1943.
Correction in:
J Bone Miner Res. 2016 Jan; 31(1): 245.
PMCID:
PMC7363154
AbstractArticlePDF–903K
13.
Core Binding Factors are essential for ovulation, luteinization, and female fertility in mice
Somang Lee-Thacker, Hayce Jeon, Yohan Choi, Ichiro Taniuchi, Takeshi Takarada, Yukio Yoneda, CheMyong Ko, Misung Jo
Sci Rep. 2020; 10: 9921. Published online 2020 Jun 18. doi: 10.1038/s41598-020-64257-0
PMCID:
PMC7303197
AbstractArticlePDF–8.1M
14.
Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity
Wooseok Seo, Kanako Shimizu, Satoshi Kojo, Arinze Okeke, Terumi Kohwi-Shigematsu, Shin-ichiro Fujii, Ichiro Taniuchi
Nat Commun. 2020; 11: 1562. Published online 2020 Mar 26. doi: 10.1038/s41467-020-15375-w
PMCID:
PMC7099032
AbstractArticlePDF–3.6M
15.
Gata2 deficiency delays leukemogenesis while contributing to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice
Satoshi Saida, Tao Zhen, Erika Kim, Kai Yu, Guadalupe Lopez, Lisa J McReynolds, Paul P Liu
Leukemia. Author manuscript; available in PMC 2020 Apr 17.
Published in final edited form as: Leukemia. 2020 Mar; 34(3): 759–770. Published online 2019 Oct 17. doi: 10.1038/s41375-019-0605-7
PMCID:
PMC7056539
AbstractArticlePDF–1.3M
16.
Essential functions of Runx/Cbfβ in gut conventional dendritic cells for priming Rorγt+ T cells
Mari Tenno, Alicia Yoke Wei Wong, Mika Ikegaya, Eiji Miyauchi, Wooseok Seo, Peter See, Tamotsu Kato, Takashi Taida, Michiko Ohno-Oishi, Hiroshi Ohno, Hideyuki Yoshida, Florent Ginhoux, Ichiro Taniuchi
Life Sci Alliance. 2020 Jan; 3(1): e201900441. Published online 2019 Dec 9. doi: 10.26508/lsa.201900441
PMCID:
PMC6907387
AbstractArticlePDF–2.1M
17.
A Thpok-directed transcriptional circuitry promotes Bcl6 and Maf to orchestrate T follicular helper differentiation.
Melanie S. Vacchio, Thomas Ciucci, Yayi Gao, Masashi Watanabe, Mariah Balmaceno-Criss, Mitchell T. McGinty, Allan Huang, Qi Xiao, Cameron McConkey, Yongmei Zhao, Jyoti Shetty, Bao Tran, Marion Pepper, Golnaz Vahedi, Marc K. Jenkins, Dorian B. McGavern, Rémy Bosselut
Immunity. Author manuscript; available in PMC 2020 Sep 17.
Published in final edited form as: Immunity. 2019 Sep 17; 51(3): 465–478.e6. Published online 2019 Aug 15. doi: 10.1016/j.immuni.2019.06.023
PMCID:
PMC6904114
AbstractArticlePDF–1.3M
18.
Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid
Safiye E. Sarper, Toshihiro Inubushi, Hiroshi Kurosaka, Hitomi Ono Minagi, Yuka Murata, Koh-ichi Kuremoto, Takayoshi Sakai, Ichiro Taniuchi, Takashi Yamashiro
Dis Model Mech. 2019 Jun 1; 12(6): dmm038851. Published online 2019 Jun 27. doi: 10.1242/dmm.038851
PMCID:
PMC6602316
AbstractArticle
19.
HDAC1 is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia
Lisa E. Richter, Yiqian Wang, Michelle E. Becker, Rachel A. Coburn, Jacob T. Williams, Catalina Amador, R. Katherine Hyde
Mol Cancer Res. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Mol Cancer Res. 2019 Jun; 17(6): 1241–1252. Published online 2019 Feb 27. doi: 10.1158/1541-7786.MCR-18-0922
PMCID:
PMC6548582
AbstractArticlePDF–1.6M
20.
Emergence and functional fitness of memory CD4+ T cells require the transcription factor Thpok
Thomas Ciucci, Melanie S. Vacchio, Yayi Gao, Francesco Tomassoni Ardori, Julian Candia, Monika Mehta, Yongmei Zhao, Bao Tran, Marion Pepper, Lino Tessarollo, Dorian B. McGavern, Rémy Bosselut
Immunity. Author manuscript; available in PMC 2020 Jan 15.
Published in final edited form as: Immunity. 2019 Jan 15; 50(1): 91–105.e4. Published online 2019 Jan 9. doi: 10.1016/j.immuni.2018.12.019
PMCID:
PMC6503975
AbstractArticlePDF–3.1M

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