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Select item 89515561.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 85026802.

ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress

Di Chen, Qiaoxia Zheng, Long Sun, Mingming Ji, Yan Li, Hongyu Deng, Hong Zhang

Dev Cell. 2021 Dec 6; 56(23): 3250–3263.e5. Published online 2021 Oct 11. doi: 10.1016/j.devcel.2021.10.006

PMCID:: PMC8502680

Abstract Article PDF–5.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72022094.

Regulation of epidermal differentiation through KDF1‐mediated deubiquitination of IKKα

Yuanyuan Li, Liangfeng Tang, Jiping Yue, Xuewen Gou, Anning Lin, Scott D Weatherbee, Xiaoyang Wu

EMBO Rep. 2020 May 6; 21(5): e48566. Published online 2020 Apr 1. doi: 10.15252/embr.201948566

PMCID:: PMC7202209

Abstract Article PDF–6.2M

Select item 63334535.

Palmitoylation controls trafficking of the intracellular Ca²⁺ channel MCOLN3/TRPML3 to regulate autophagy

So Woon Kim, Dong Hyun Kim, Kyoung Sun Park, Mi Kyung Kim, Yun Min Park, Shmuel Muallem, Insuk So, Hyun Jin Kim

Autophagy. 2019; 15(2): 327–340. Published online 2018 Sep 14. doi: 10.1080/15548627.2018.1518671

PMCID:: PMC6333453

Abstract Article PDF–3.3M

Select item 61055606.

The regulatory mechanism of mammalian TRPMLs revealed by cryo-EM

Philip Schmiege, Michael Fine, Xiaochun Li

FEBS J. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: FEBS J. 2018 Jul; 285(14): 2579–2585. Published online 2018 Apr 14. doi: 10.1111/febs.14443

PMCID:: PMC6105560

Abstract Article PDF–1.4M

Select item 60777227.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 46172119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 419687610.

Lysosomal Localization of TRPML3 Depends on TRPML2 and the Mucolipidosis-associated Protein TRPML1

Kartik Venkatachalam, Thomas Hofmann, Craig Montell

J Biol Chem. Author manuscript; available in PMC 2014 Oct 14.

Published in final edited form as: J Biol Chem. 2006 Jun 23; 281(25): 17517–17527. Published online 2006 Apr 10. doi: 10.1074/jbc.M600807200

PMCID:: PMC4196876

Abstract Article PDF–909K

Select item 358526311.

A Novel Ion Channel Formed by Interaction of TRPML3 with TRPV5

Zhaohua Guo, Christian Grimm, Lars Becker, Anthony J. Ricci, Stefan Heller

PLoS One. 2013; 8(2): e58174. Published online 2013 Feb 28. doi: 10.1371/journal.pone.0058174

PMCID:: PMC3585263

Abstract Article PDF–868K

Select item 339112412.

Constitutive Activity of TRPML2 and TRPML3 Channels versus Activation by Low Extracellular Sodium and Small Molecules

Christian Grimm, Simone Jörs, Zhaohua Guo, Alexander G. Obukhov, Stefan Heller

J Biol Chem. 2012 Jun 29; 287(27): 22701–22708. Published online 2012 May 9. doi: 10.1074/jbc.M112.368876

PMCID:: PMC3391124

Abstract Article PDF–1.9M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 299350714.

The Ca²⁺ Channel TRPML3 Regulates Membrane Trafficking and Autophagy

Hyun Jin Kim, Abigail A. Soyombo, Sandra Tjon-Kon-Sang, Insuk So, Shmuel Muallem

Traffic. Author manuscript; available in PMC 2010 Nov 29.

Published in final edited form as: Traffic. 2009 Aug; 10(8): 1157–1167. Published online 2009 May 11. doi: 10.1111/j.1600-0854.2009.00924.x

PMCID:: PMC2993507

Abstract Article PDF–1.5M

Select item 295585915.

The Calcium Channel Mucolipin-3 is a Novel Regulator of Trafficking Along the Endosomal Pathway

Jose A. Martina, Benjamin Lelouvier, Rosa Puertollano

Traffic. Author manuscript; available in PMC 2010 Oct 16.

Published in final edited form as: Traffic. 2009 Aug; 10(8): 1143–1156. Published online 2009 Apr 29. doi: 10.1111/j.1600-0854.2009.00935.x

PMCID:: PMC2955859

Abstract Article PDF–2.2M

Select item 293160516.

Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy

David A. Zeevi, Shaya Lev, Ayala Frumkin, Baruch Minke, Gideon Bach

J Cell Sci. 2010 Sep 15; 123(18): 3112–3124. Published online 2010 Aug 24. doi: 10.1242/jcs.067330

PMCID:: PMC2931605

Abstract Article

Select item 287803117.

Properties of the TRPML3 Channel Pore and Its Stable Expansion by the Varitint-Waddler-causing Mutation

Hyun Jin Kim, Soichiro Yamaguchi, Qin Li, Insuk So, Shmuel Muallem

J Biol Chem. 2010 May 28; 285(22): 16513–16520. Published online 2010 Apr 8. doi: 10.1074/jbc.M109.078204

PMCID:: PMC2878031

Abstract Article PDF–1.6M

Select item 267948318.

Life and Death of Sensory Hair Cells Expressing Constitutively Active TRPML3

Christian Grimm, Simone Jörs, Stefan Heller

J Biol Chem. 2009 May 15; 284(20): 13823–13831. doi: 10.1074/jbc.M809045200

PMCID:: PMC2679483

Abstract Article PDF–1.0M

Select item 236740019.

A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype

Hyun Jin Kim, Qin Li, Sandra Tjon-Kon-Sang, Insuk So, Kirill Kiselyov, Abigail A Soyombo, Shmuel Muallem

EMBO J. 2008 Apr 23; 27(8): 1197–1205. Published online 2008 Mar 27. doi: 10.1038/emboj.2008.56

PMCID:: PMC2367400

Abstract Article PDF–590K

Select item 222421620.

The varitint-waddler (Va) deafness mutation in TRPML3 generates constitutive, inward rectifying currents and causes cell degeneration

Keiichi Nagata, Lili Zheng, Thomas Madathany, Andrew J. Castiglioni, James R. Bartles, Jaime García-Añoveros

Proc Natl Acad Sci U S A. 2008 Jan 8; 105(1): 353–358. Published online 2007 Dec 27. doi: 10.1073/pnas.0707963105

PMCID:: PMC2224216

Abstract Article PDF–1.2M

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