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Items: 1 to 20 of 29

1.
Epidermal keratinocytes regulate hyaluronan metabolism via extracellularly secreted hyaluronidase 1 and hyaluronan synthase 3
Minori Abe, Manami Masuda, Yoichi Mizukami, Shintaro Inoue, Yukiko Mizutani
J Biol Chem. 2024 Jul; 300(7): 107449. Published online 2024 Jun 4. doi: 10.1016/j.jbc.2024.107449
PMCID:
PMC11292368
AbstractArticlePDF–1.2M
2.
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression
Ashik Jawahar Deen, Uma Thanigai Arasu, Sanna Pasonen-Seppänen, Antti Hassinen, Piia Takabe, Sara Wojciechowski, Riikka Kärnä, Kirsi Rilla, Sakari Kellokumpu, Raija Tammi, Markku Tammi, Sanna Oikari
Cell Mol Life Sci. 2016 Aug; 73(16): 3183–3204. Published online 2016 Feb 16. doi: 10.1007/s00018-016-2158-5
PMCID:
PMC11108457
AbstractArticlePDF–17M
3.
4-Methylumebelliferone Enhances Radiosensitizing Effects of Radioresistant Oral Squamous Cell Carcinoma Cells via Hyaluronan Synthase 3 Suppression
Kazuki Hasegawa, Ryo Saga, Kentaro Ohuchi, Yoshikazu Kuwahara, Kazuo Tomita, Kazuhiko Okumura, Tomoaki Sato, Manabu Fukumoto, Eichi Tsuruga, Yoichiro Hosokawa
Cells. 2022 Dec; 11(23): 3780. Published online 2022 Nov 25. doi: 10.3390/cells11233780
PMCID:
PMC9741296
AbstractArticlePDF–1.9M
4.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
5.
A Connecting Link between Hyaluronan Synthase 3-Mediated Hyaluronan Production and Epidermal Function
Yukiko Ota, Hiroyuki Yoshida, Yoko Endo, Tetsuya Sayo, Yoshito Takahashi
Int J Mol Sci. 2022 Mar; 23(5): 2424. Published online 2022 Feb 22. doi: 10.3390/ijms23052424
PMCID:
PMC8910372
AbstractArticlePDF–18M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells
Uma Thanigai Arasu, Ashik Jawahar Deen, Sanna Pasonen-Seppänen, Sami Heikkinen, Maciej Lalowski, Riikka Kärnä, Kai Härkönen, Petri Mäkinen, Elisa Lázaro-Ibáñez, Pia R-M Siljander, Sanna Oikari, Anna-Liisa Levonen, Kirsi Rilla
Cell Mol Life Sci. 2020 Oct; 77(20): 4093–4115. Published online 2019 Dec 9. doi: 10.1007/s00018-019-03399-5
PMCID:
PMC7532973
AbstractArticlePDF–9.1M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Hyaluronan synthase 3 promotes plaque inflammation and atheroprogression
Susanne Homann, Maria Grandoch, Lena S. Kiene, Yanina Podsvyadek, Kathrin Feldmann, Berit Rabausch, Nadine Nagy, Stefan Lehr, Inga Kretschmer, Alexander Oberhuber, Paul Bollyky, Jens W. Fischer
Matrix Biol. Author manuscript; available in PMC 2018 Jun 28.
Published in final edited form as: Matrix Biol. 2018 Mar; 66: 67–80. Published online 2017 Oct 5. doi: 10.1016/j.matbio.2017.09.005
PMCID:
PMC6023397
AbstractArticlePDF–874K
10.
miR-29a-3p represses proliferation and metastasis of gastric cancer cells via attenuating HAS3 levels
Feihu Bai, Mengna Jiu, Yanjie You, Yaning Feng, Ruijuan Xin, Xiaogang Liu, Lirong Mo, Yongzhan Nie
Mol Med Rep. 2018 Jun; 17(6): 8145–8152. Published online 2018 Apr 19. doi: 10.3892/mmr.2018.8896
PMCID:
PMC5983988
AbstractArticlePDF–1.5M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer
Yi-Zih Kuo, Wei-Yu Fang, Cheng-Chih Huang, Sen-Tien Tsai, Yi-Ching Wang, Chih-Li Yang, Li-Wha Wu
Oncotarget. 2017 Feb 28; 8(9): 15563–15583. Published online 2017 Jan 17. doi: 10.18632/oncotarget.14697
PMCID:
PMC5362506
AbstractArticlePDF–5.5M
13.
Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo- and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3
Geneviève Bart, Nuria Ortega Vico, Antti Hassinen, Francois M. Pujol, Ashik Jawahar Deen, Aino Ruusala, Raija H. Tammi, Anthony Squire, Paraskevi Heldin, Sakari Kellokumpu, Markku I. Tammi
J Biol Chem. 2015 May 1; 290(18): 11479–11490. Published online 2015 Mar 20. doi: 10.1074/jbc.M115.640581
PMCID:
PMC4416852
AbstractArticlePDF–1.9M
14.
Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment
Anne Kultti, Chunmei Zhao, Netai C. Singha, Susan Zimmerman, Ryan J. Osgood, Rebecca Symons, Ping Jiang, Xiaoming Li, Curtis B. Thompson, Jeffrey R. Infante, Michael A. Jacobetz, David A. Tuveson, Gregory I. Frost, H. Michael Shepard, Zhongdong Huang
Biomed Res Int. 2014; 2014: 817613. Published online 2014 Jul 24. doi: 10.1155/2014/817613
PMCID:
PMC4131462
AbstractArticlePDF–8.3M
15.
Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen
Ashik Jawahar Deen, Kirsi Rilla, Sanna Oikari, Riikka Kärnä, Genevieve Bart, Jukka Häyrinen, Avinash Rahul Bathina, Antti Ropponen, Katri Makkonen, Raija H. Tammi, Markku I. Tammi
J Biol Chem. 2014 Mar 21; 289(12): 8375–8389. Published online 2014 Feb 7. doi: 10.1074/jbc.M114.552133
PMCID:
PMC3961663
AbstractArticlePDF–4.1M
16.
Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group
Xuexia Wang, Wei Liu, Can-Lan Sun, Saro H. Armenian, Hakon Hakonarson, Lindsey Hageman, Yan Ding, Wendy Landier, Javier G. Blanco, Lu Chen, Adolfo Quiñones, Daniel Ferguson, Naomi Winick, Jill P. Ginsberg, Frank Keller, Joseph P. Neglia, Sunil Desai, Charles A. Sklar, Sharon M. Castellino, Irene Cherrick, ZoAnn E. Dreyer, Melissa M. Hudson, Leslie L. Robison, Yutaka Yasui, Mary V. Relling, Smita Bhatia
J Clin Oncol. 2014 Mar 1; 32(7): 647–653. Published online 2014 Jan 27. doi: 10.1200/JCO.2013.50.3557
PMCID:
PMC3927733
AbstractArticlePDF–912K
17.
Oxidized Low Density Lipoprotein (LDL) Affects Hyaluronan Synthesis in Human Aortic Smooth Muscle Cells
Manuela Viola, Barbara Bartolini, Davide Vigetti, Evgenia Karousou, Paola Moretto, Sara Deleonibus, Tatsuya Sawamura, Thomas N. Wight, Vincent C. Hascall, Giancarlo De Luca, Alberto Passi
J Biol Chem. 2013 Oct 11; 288(41): 29595–29603. Published online 2013 Aug 26. doi: 10.1074/jbc.M113.508341
PMCID:
PMC3795257
AbstractArticlePDF–914K
18.
Inverse expression of hyaluronidase 2 and hyaluronan synthases 1–3 is associated with reduced hyaluronan content in malignant cutaneous melanoma
Siiskonen Hanna, Poukka Mari, Tyynelä-Korhonen Kristiina, Sironen Reijo, Pasonen-Seppänen Sanna
BMC Cancer. 2013; 13: 181. Published online 2013 Apr 5. doi: 10.1186/1471-2407-13-181
PMCID:
PMC3626669
AbstractArticlePDF–1.8M
19.
Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3
Kirsi Rilla, Sanna Oikari, Tiina A. Jokela, Juha M. T. Hyttinen, Riikka Kärnä, Raija H. Tammi, Markku I. Tammi
J Biol Chem. 2013 Feb 22; 288(8): 5973–5983. Published online 2013 Jan 9. doi: 10.1074/jbc.M112.443879
PMCID:
PMC3581382
AbstractArticlePDF–2.7M
20.
Perturbation of Hyaluronan Synthesis in the Trabecular Meshwork and the Effects on Outflow Facility
Kate E. Keller, Ying Ying Sun, Yong-Feng Yang, John M. Bradley, Ted S. Acott
Invest Ophthalmol Vis Sci. 2012 Jul; 53(8): 4616–4625. Published online 2012 Jul 9. doi: 10.1167/iovs.12-9500
PMCID:
PMC3394696
AbstractArticlePDF–1003K

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