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Items: 1 to 20 of 53

1.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
2.
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Yu-Han H. Hsu, Greta Pintacuda, Ruize Liu, Eugeniu Nacu, April Kim, Kalliopi Tsafou, Natalie Petrossian, William Crotty, Jung Min Suh, Jackson Riseman, Jacqueline M. Martin, Julia C. Biagini, Daya Mena, Joshua K.T. Ching, Edyta Malolepsza, Taibo Li, Tarjinder Singh, Tian Ge, Shawn B. Egri, Benjamin Tanenbaum, Caroline R. Stanclift, Annie M. Apffel, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Steven A. Carr, Monica Schenone, Jake Jaffe, Nadine Fornelos, Hailiang Huang, Kevin C. Eggan, Kasper Lage
iScience. 2023 May 19; 26(5): 106701. Published online 2023 Apr 18. doi: 10.1016/j.isci.2023.106701
PMCID:
PMC10189495
AbstractArticlePDF–5.3M
3.
Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop
Tingting Xu, Mengyan Xie, Xinming Jing, Huning Jiang, Xi Wu, Xinzhu Wang, Yongqian Shu
J Transl Med. 2023; 21: 77. Published online 2023 Feb 3. doi: 10.1186/s12967-023-03933-x
PMCID:
PMC9898947
AbstractArticlePDF–11M
4.
Population genetics of PDE4B (phosphodiesterase‐4B) in neglected Native Americans: Implications for cancer pharmacogenetics
Rennan Garcias Moreira, Julia Maria Saraiva‐Duarte, Alexandre Costa Pereira, Martha Sosa‐Macias, Carlos Galaviz‐Hernandez, Meddly Lesley Santolalla, Wagner C. S. Magalhães, Camila Zolini, Thiago Peixoto Leal, Zsolt Balázs, Adrián Llerena, Robert H. Gilman, José Geraldo Mill, Victor Borda, Heinner Guio, Timothy D. O’Connor, Eduardo Tarazona‐Santos, Fernanda Rodrigues‐Soares
Clin Transl Sci. 2022 Jun; 15(6): 1400–1405. Published online 2022 Mar 28. doi: 10.1111/cts.13266
PMCID:
PMC9199872
AbstractArticlePDF–889K
5.
Long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) sponges microRNA-124-3p to up-regulate phosphodiesterase 4B (PDE4B) to accelerate the progression of Parkinson’s disease
Ming-Yu Chen, Kai Fan, Lian-Jiang Zhao, Jie-Mei Wei, Ji-Xu Gao, Zhen-Fu Li
Bioengineered. 2021; 12(1): 708–719. Published online 2021 Feb 22. doi: 10.1080/21655979.2021.1883279
PMCID:
PMC8806245
AbstractArticlePDF–2.2M
6.
qPCR Analysis Reveals Association of Differential Expression of SRR, NFKB1, and PDE4B Genes With Type 2 Diabetes Mellitus
Waseem Raza, Jinlei Guo, Muhammad Imran Qadir, Baogang Bai, Syed Aun Muhammad
Front Endocrinol (Lausanne) 2021; 12: 774696. Published online 2022 Jan 3. doi: 10.3389/fendo.2021.774696
PMCID:
PMC8761634
AbstractArticlePDF–7.2M
7.
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1
Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang
Ann Rheum Dis. 2021 Sep; 80(9): 1209–1219. Published online 2021 May 26. doi: 10.1136/annrheumdis-2021-219969
PMCID:
PMC8372377
AbstractArticlePDF–7.8M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Expression of Phosphodiesterase 4B cAMP‐Specific Gene in Subjects With Cryptorchidism and Down's Syndrome
Michele Salemi, Rosita A. Condorelli, Sandro La Vignera, Roberto Castiglione, Maria Grazia Salluzzo, Carmela M. Bonaccorso, Mirella Vinci, Paolo Bosco, Carmelo Romano, Cristina Campagna, Corrado Romano, Aldo E. Calogero
J Clin Lab Anal. 2016 May; 30(3): 196–199. Published online 2014 Dec 26. doi: 10.1002/jcla.21835
PMCID:
PMC6807182
AbstractArticlePDF–482K
10.
Isoform-Selective Susceptibility of DISC1/Phosphodiesterase-4 Complexes to Dissociation by Elevated Intracellular cAMP Levels
Hannah Murdoch, Shaun Mackie, Daniel M. Collins, Elaine V. Hill, Graeme B. Bolger, Enno Klussmann, David J. Porteous, J. Kirsty Millar, Miles D. Houslay
J Neurosci. 2007 Aug 29; 27(35): 9513–9524. doi: 10.1523/JNEUROSCI.1493-07.2007
PMCID:
PMC6673124
AbstractArticlePDF–5.9M
11.
Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study
Sandra M. Meier, Kalevi Trontti, Kirstin L. Purves, Thomas Damm Als, Jakob Grove, Mikaela Laine, Marianne Giørtz Pedersen, Jonas Bybjerg-Grauholm, Marie Bækved-Hansen, Ewa Sokolowska, Preben B. Mortensen, David M. Hougaard, Thomas Werge, Merete Nordentoft, Gerome Breen, Anders D. Børglum, Thalia C. Eley, Iiris Hovatta, Manuel Mattheisen, Ole Mors
JAMA Psychiatry. 2019 Sep; 76(9): 924–932. Published online 2019 May 22. doi: 10.1001/jamapsychiatry.2019.1119
PMCID:
PMC6537792
AbstractArticle
12.
The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer
Jennifer K. Pleiman, Amy A. Irving, Zhishi Wang, Erik Toraason, Linda Clipson, William F. Dove, Dustin A. Deming, Michael A. Newton
PLoS Genet. 2018 Sep; 14(9): e1007611. Published online 2018 Sep 6. doi: 10.1371/journal.pgen.1007611
PMCID:
PMC6143270
AbstractArticlePDF–8.4M
13.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
14.
Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington’s disease
Motomasa Tanaka, Koko Ishizuka, Yoko Nekooki-Machida, Ryo Endo, Noriko Takashima, Hideyuki Sasaki, Yusuke Komi, Amy Gathercole, Elaine Huston, Kazuhiro Ishii, Kelvin Kai-Wan Hui, Masaru Kurosawa, Sun-Hong Kim, Nobuyuki Nukina, Eiki Takimoto, Miles D. Houslay, Akira Sawa
J Clin Invest. 2017 Apr 3; 127(4): 1438–1450. Published online 2017 Mar 6. doi: 10.1172/JCI85594
PMCID:
PMC5373889
AbstractArticlePDF–2.1M
15.
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning
Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich
eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466
PMCID:
PMC4764573
AbstractArticlePDF–5.7M
16.
Association of PDE4B Polymorphisms with Susceptibility to Schizophrenia: A Meta-Analysis of Case-Control Studies
Yanguo Feng, Dejun Cheng, Chaofeng Zhang, Yuchun Li, Zhiying Zhang, Juan Wang, Yuzhong Shi
PLoS One. 2016; 11(1): e0147092. Published online 2016 Jan 12. doi: 10.1371/journal.pone.0147092
PMCID:
PMC4710508
AbstractArticlePDF–1.8M
17.
Gene Set Enrichment Analysis Unveils the Mechanism for the Phosphodiesterase 4B Control of Glucocorticoid Response in B-cell Lymphoma
Sang-Woo Kim, Deepak Rai, Ricardo C.T. Aguiar
Clin Cancer Res. Author manuscript; available in PMC 2015 Nov 18.
Published in final edited form as: Clin Cancer Res. 2011 Nov 1; 17(21): 6723–6732. Published online 2011 Jul 8. doi: 10.1158/1078-0432.CCR-11-0770
PMCID:
PMC4651210
AbstractArticlePDF–986K
18.
Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi
Seiko Susuki-Miyata, Masanori Miyata, Byung-Cheol Lee, Haidong Xu, Hirofumi Kai, Chen Yan, Jian-Dong Li
Proc Natl Acad Sci U S A. 2015 Apr 7; 112(14): E1800–E1809. Published online 2015 Mar 23. doi: 10.1073/pnas.1418716112
PMCID:
PMC4394257
AbstractArticlePDF–1.6M
19.
Ibudilast (AV411), and its AV1013 analogue, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine
Nazira EL-HAGE, Myosotys RODRIGUEZ, Elizabeth M. PODHAIZER, Shiping ZOU, Seth M. DEVER, Sarah E. SNIDER, Pamela E. KNAPP, Patrick M. BEARDSLEY, Kurt F. HAUSER
AIDS. Author manuscript; available in PMC 2015 Jun 19.
Published in final edited form as: AIDS. 2014 Jun 19; 28(10): 1409–1419. doi: 10.1097/QAD.0000000000000291
PMCID:
PMC4300098
ArticlePDF–695K
20.
Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections
Zhan Ye, Daniel A. Vasco, Tonia C. Carter, Murray H. Brilliant, Steven J. Schrodi, Sanjay K. Shukla
Front Genet. 2014; 5: 125. Published online 2014 May 9. doi: 10.3389/fgene.2014.00125
PMCID:
PMC4023021
AbstractArticlePDF–1.4M

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