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Select item 109455081.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109401662.

Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila

James H. Catterson, Lucy Minkley, Salomé Aspe, Sebastian Judd-Mole, Sofia Moura, Miranda C. Dyson, Arjunan Rajasingam, Nathaniel S. Woodling, Magda L. Atilano, Mumtaz Ahmad, Claire S. Durrant, Tara L. Spires-Jones, Linda Partridge

Neurobiol Aging. 2023 Dec; 132: 154–174. doi: 10.1016/j.neurobiolaging.2023.09.008

PMCID:: PMC10940166

Abstract Article PDF–16M

Select item 109177973.

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Yue Li, Tianfeng Lu, Pengzhen Dong, Jian Chen, Qiang Zhao, Yuying Wang, Tianheng Xiao, Honggang Wu, Quanyi Zhao, Hai Huang

Nat Commun. 2024; 15: 2019. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46455-w

PMCID:: PMC10917797

Abstract Article PDF–5.3M

Select item 107218034.

Akaluc/AkaLumine bioluminescence system enables highly sensitive, non-invasive and temporal monitoring of gene expression in Drosophila

Akira Ito, Nagisa Matsuda, Yumiko Ukita, Misako Okumura, Takahiro Chihara

Commun Biol. 2023; 6: 1270. Published online 2023 Dec 14. doi: 10.1038/s42003-023-05628-x

PMCID:: PMC10721803

Abstract Article PDF–2.4M

Select item 104741265.

Nacα protects the larval fat body from cell death by maintaining cellular proteostasis in Drosophila

Takayuki Yamada, Yuto Yoshinari, Masayuki Tobo, Okiko Habara, Takashi Nishimura

Nat Commun. 2023; 14: 5328. Published online 2023 Sep 1. doi: 10.1038/s41467-023-41103-1

PMCID:: PMC10474126

Abstract Article PDF–13M

Select item 103916756.

The tardigrade Dsup protein enhances radioresistance in Drosophila melanogaster and acts as an unspecific repressor of transcription

Mikhail Zarubin, Talyana Azorskaya, Olga Kuldoshina, Sergey Alekseev, Semen Mitrofanov, Elena Kravchenko

iScience. 2023 Jul 21; 26(7): 106998. Published online 2023 May 29. doi: 10.1016/j.isci.2023.106998

PMCID:: PMC10391675

Abstract Article PDF–3.0M

Select item 103356547.

Deep data mining reveals variable abundance and distribution of microbial reproductive manipulators within and among diverse host species

Paloma Medina, Shelbi L. Russell, Russell Corbett-Detig

PLoS One. 2023; 18(7): e0288261. Published online 2023 Jul 11. doi: 10.1371/journal.pone.0288261

PMCID:: PMC10335654

Abstract Article PDF–1.6M

Select item 102677518.

Preservation of ∼12-h ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock

Bokai Zhu, Silvia Liu

Front Physiol. 2023; 14: 1195001. Published online 2023 May 30. doi: 10.3389/fphys.2023.1195001

PMCID:: PMC10267751

Abstract Article PDF–3.5M

Select item 100823679.

PERK prevents rhodopsin degradation during retinitis pigmentosa by inhibiting IRE1-induced autophagy

Ning Zhao, Ning Li, Tao Wang

J Cell Biol. 2023 May 1; 222(5): e202208147. Published online 2023 Apr 6. doi: 10.1083/jcb.202208147

PMCID:: PMC10082367

Abstract Article PDF–8.9M

Select item 1007891710.

A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi

William W Fisher, Ann S Hammonds, Richard Weiszmann, Benjamin W Booth, Louis Gevirtzman, Jaeda E J Patton, Connor A Kubo, Robert H Waterston, Susan E Celniker

Genetics. 2023 Apr; 223(4): iyad004. Published online 2023 Jan 19. doi: 10.1093/genetics/iyad004

PMCID:: PMC10078917

Abstract Article PDF–18M

Select item 1006122311.

Inhibition of endoplasmic reticulum stress signaling rescues cytotoxicity of human apolipoprotein-L1 risk variants in Drosophila

Lea Gerstner, Mengmeng Chen, Lina L. Kampf, Julian Milosavljevic, Konrad Lang, Ronen Schneider, Friedhelm Hildebrandt, Martin Helmstädter, Gerd Walz, Tobias Hermle

Kidney Int. Author manuscript; available in PMC 2023 Mar 30.

Published in final edited form as: Kidney Int. 2022 Jun; 101(6): 1216–1231. Published online 2022 Feb 1. doi: 10.1016/j.kint.2021.12.031

PMCID:: PMC10061223

Abstract Article PDF–5.3M

Select item 989350812.

Endoplasmic reticulum-associated protein degradation contributes to Toll innate immune defense in Drosophila melanogaster

Yangyang Zhu, Lei Liu, Chuchu Zhang, Chao Zhang, Tingting Han, Renjie Duan, Yiheng Jin, Huimin Guo, Kan She, Yihua Xiao, Akira Goto, Qingshuang Cai, Shanming Ji

Front Immunol. 2022; 13: 1099637. Published online 2023 Jan 19. doi: 10.3389/fimmu.2022.1099637

PMCID:: PMC9893508

Abstract Article PDF–7.0M

Select item 983568913.

The complex role of transcription factor GAGA in germline death during Drosophila spermatogenesis: transcriptomic and bioinformatic analyses

Svetlana Fedorova, Natalya V. Dorogova, Dmitriy A. Karagodin, Dmitry Yu Oshchepkov, Ilya I. Brusentsov, Natalya V. Klimova, Elina M. Baricheva

PeerJ. 2023; 11: e14063. Published online 2023 Jan 9. doi: 10.7717/peerj.14063

PMCID:: PMC9835689

Abstract Article PDF–1.1M

Select item 971343114.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 964167015.

Regulation of Archease by the mTOR-vATPase axis

Deanne Francis, Alondra S. Burguete, Amin S. Ghabrial

Development. 2022 Oct 1; 149(19): dev200908. Published online 2022 Oct 7. doi: 10.1242/dev.200908

PMCID:: PMC9641670

Abstract Article

Select item 961699916.

A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response

Tyler A. U. Hilsabeck, Ru Liu-Bryan, Tracy Guo, Kenneth A. Wilson, Neelanjan Bose, Daniel Raftery, Jennifer N. Beck, Sven Lang, Kelly Jin, Christopher S. Nelson, Tal Oron, Marshall Stoller, Daniel Promislow, Rachel B. Brem, Robert Terkeltaub, Pankaj Kapahi

GeroScience. 2022 Aug; 44(4): 2195–2211. Published online 2022 Apr 6. doi: 10.1007/s11357-022-00557-9

PMCID:: PMC9616999

Abstract Article PDF–3.9M

Select item 958632117.

Bip-Yorkie interaction determines oncogenic and tumor-suppressive roles of Ire1/Xbp1s activation

Shuai Yang, Hua Jiang, Weixiang Bian, Wenyan Xu, Yifan Guo, Sha Song, Jiadong Zheng, Xiaoyu Kuang, Chenxi Wu, Xiang Ding, Xiaowei Guo, Lei Xue, Zijing Yu, Yongdeng Zhang, Hyung Don Ryoo, Xu Li, Xianjue Ma

Proc Natl Acad Sci U S A. 2022 Oct 18; 119(42): e2202133119. Published online 2022 Oct 10. doi: 10.1073/pnas.2202133119