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Select item 105031901.

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert Vassar, Diego E. Rincon-Limas, Jeffrey N. Savas

Mol Neurodegener. 2023; 18: 61. Published online 2023 Sep 14. doi: 10.1186/s13024-023-00654-z

PMCID:: PMC10503190

Abstract Article PDF–8.6M

Select item 81491252.

Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis

Tarik Seref Onur, Andrew Laitman, He Zhao, Ryan Keyho, Hyemin Kim, Jennifer Wang, Megan Mair, Huilan Wang, Lifang Li, Alma Perez, Maria de Haro, Ying-Wooi Wan, Genevera Allen, Boxun Lu, Ismael Al-Ramahi, Zhandong Liu, Juan Botas

eLife. 2021; 10: e64564. Published online 2021 Apr 19. doi: 10.7554/eLife.64564

PMCID:: PMC8149125

Abstract Article PDF–3.5M

Select item 80422703.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 77719634.

A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signaling

Deepti Trivedi, Vinitha CM, Karishma Bisht, Vishnu Janardan, Awadhesh Pandit, Bishal Basak, Shwetha H, Navyashree Ramesh, Padinjat Raghu

eLife. 2020; 9: e55793. Published online 2020 Dec 15. doi: 10.7554/eLife.55793

PMCID:: PMC7771963

Abstract Article PDF–1.6M

Select item 74750355.

Understanding the Early Evolutionary Stages of a Tandem Drosophilamelanogaster-Specific Gene Family: A Structural and Functional Population Study

Bryan D Clifton, Jamie Jimenez, Ashlyn Kimura, Zeinab Chahine, Pablo Librado, Alejandro Sánchez-Gracia, Mashya Abbassi, Francisco Carranza, Carolus Chan, Marcella Marchetti, Wanting Zhang, Mijuan Shi, Christine Vu, Shudan Yeh, Laura Fanti, Xiao-Qin Xia, Julio Rozas, José M Ranz

Mol Biol Evol. 2020 Sep; 37(9): 2584–2600. Published online 2020 May 2. doi: 10.1093/molbev/msaa109

PMCID:: PMC7475035

Abstract Article PDF–798K

Select item 69615786.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 64046607.

Rapid Functional and Sequence Differentiation of a Tandemly Repeated Species-Specific Multigene Family in Drosophila

Bryan D. Clifton, Pablo Librado, Shu-Dan Yeh, Edwin S. Solares, Daphne A. Real, Suvini U. Jayasekera, Wanting Zhang, Mijuan Shi, Ronni V. Park, Robert D. Magie, Hsiu-Ching Ma, Xiao-Qin Xia, Antonio Marco, Julio Rozas, José M. Ranz

Mol Biol Evol. 2017 Jan; 34(1): 51–65. Published online 2016 Oct 3. doi: 10.1093/molbev/msw212

PMCID:: PMC6404660

Abstract Article PDF–1023K

Select item 64005518.

Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix

Nicole Scholz, Nadine Ehmann, Divya Sachidanandan, Cordelia Imig, Benjamin H. Cooper, Olaf Jahn, Kerstin Reim, Nils Brose, Jutta Meyer, Marius Lamberty, Steffen Altrichter, Anne Bormann, Stefan Hallermann, Martin Pauli, Manfred Heckmann, Christian Stigloher, Tobias Langenhan, Robert J. Kittel

J Cell Biol. 2019 Mar 4; 218(3): 1011–1026. doi: 10.1083/jcb.201806155

PMCID:: PMC6400551

Abstract Article PDF–2.9M

Select item 62427049.

Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy

Stanley M. Walls, Anthony Cammarato, Dale A. Chatfield, Karen Ocorr, Greg L. Harris, Rolf Bodmer

Cell Rep. Author manuscript; available in PMC 2018 Nov 19.

Published in final edited form as: Cell Rep. 2018 Mar 6; 22(10): 2702–2715. doi: 10.1016/j.celrep.2018.02.034

PMCID:: PMC6242704

Abstract Article PDF–4.6M

Select item 607860410.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 570780511.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900212.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 539197013.

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases

Rachel A. Kline, Kevin A. Kaifer, Erkan Y. Osman, Francesco Carella, Ariana Tiberi, Jolill Ross, Giuseppa Pennetta, Christian L. Lorson, Lyndsay M. Murray

PLoS Genet. 2017 Mar; 13(3): e1006680. Published online 2017 Mar 31. doi: 10.1371/journal.pgen.1006680

PMCID:: PMC5391970

Abstract Article PDF–1.5M

Select item 531200414.

Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis

Wei-Hsiang Lin, Carlo N. G. Giachello, Richard A. Baines

Dis Model Mech. 2017 Feb 1; 10(2): 141–150. doi: 10.1242/dmm.027045

PMCID:: PMC5312004

Abstract Article

Select item 493747415.

Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9

Silvia Schwartz, Mauro Truglio, Maxwell J. Scott, Helen L. Fitzsimons

Genetics. 2016 Jul; 203(3): 1249–1264. Published online 2016 May 3. doi: 10.1534/genetics.115.183194

PMCID:: PMC4937474

Abstract Article PDF–2.3M

Select item 460415416.

Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells

Juanma Ramirez, Aitor Martinez, Benoit Lectez, So Young Lee, Maribel Franco, Rosa Barrio, Gunnar Dittmar, Ugo Mayor

PLoS One. 2015; 10(10): e0139083. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0139083

PMCID:: PMC4604154

Abstract Article PDF–3.1M

Select item 459299617.

SUMO-Enriched Proteome for Drosophila Innate Immune Response

Mithila Handu, Bhagyashree Kaduskar, Ramya Ravindranathan, Amarendranath Soory, Ritika Giri, Vijay Barathi Elango, Harsha Gowda, Girish S. Ratnaparkhi

G3 (Bethesda) 2015 Oct; 5(10): 2137–2154. Published online 2015 Aug 18. doi: 10.1534/g3.115.020958

PMCID:: PMC4592996

Abstract Article PDF–2.0M

Select item 452833018.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832919.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929