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Items: 1 to 20 of 33

1.
The role of WTAP in regulating macrophage-mediated osteoimmune responses and tissue regeneration in periodontitis
Yuman Li, Yue Yang, Yuting Niu, Yao Li, Zhewen Hu, Shiyu Sun, Yiming Chen, Bo Hu, Ying Huang, Xuliang Deng
Front Immunol. 2024; 15: 1423378. Published online 2024 Jul 16. doi: 10.3389/fimmu.2024.1423378
PMCID:
PMC11286459
AbstractArticlePDF–7.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2–ERK depending on downregulation of proteasome-related genes
Xinzhi Li, Chunhong Liu, Zhimin Zhang, Xueying Li, Zhicheng Yao, Yanbin Dong, Xin Wang, Zheng Chen
J Biol Chem. 2023 Nov; 299(11): 105301. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105301
PMCID:
PMC10630636
AbstractArticlePDF–2.9M
4.
Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells
Liang Li, Yue Sun, Alexander E. Davis, Sahil H. Shah, Lobna K. Hamed, Man-Ru Wu, Cheng-Hui Lin, Jun B. Ding, Sui Wang
Cell Rep. Author manuscript; available in PMC 2023 Oct 2.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112596. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112596
PMCID:
PMC10543643
AbstractArticlePDF–3.9M
5.
WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis
Jincheng Liu, Yunhao You, Zhenqian Sun, Lu Zhang, Xiang Li, Zihan Dai, Jinlong Ma, Yunzhen Chen, Guangjun Jiao
Stem Cells Transl Med. 2023 May; 12(5): 307–321. Published online 2023 Apr 3. doi: 10.1093/stcltm/szad020
PMCID:
PMC10184703
AbstractArticlePDF–61M
6.
WTAP-mediated m6A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis
Yunhao You, Jincheng Liu, Lu Zhang, Xiang Li, Zhenqian Sun, Zihan Dai, Jinlong Ma, Guangjun Jiao, Yunzhen Chen
Cell Death Dis. 2023 Jan; 14(1): 33. Published online 2023 Jan 17. doi: 10.1038/s41419-023-05565-x
PMCID:
PMC9845239
AbstractArticlePDF–7.2M
7.
N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis
Furong Xie, Xueqin Zhu, Xiao Liu, Hui Chen, Jun Wang
J Biol Chem. 2022 Dec; 298(12): 102715. Published online 2022 Nov 17. doi: 10.1016/j.jbc.2022.102715
PMCID:
PMC9791132
AbstractArticlePDF–5.5M
8.
PGE2‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase
Xixi Tao, Ronglu Du, Shumin Guo, Xiangling Feng, Tingting Yu, Qian OuYang, Qiaoli Chen, Xutong Fan, Xueqi Wang, Chen Guo, Xiaozhou Li, Fengxia Xue, Shuai Chen, Minghan Tong, Michael Lazarus, Shengkai Zuo, Ying Yu, Yujun Shen
EMBO J. 2022 Aug; 41(16): e110439. Published online 2022 Jul 4. doi: 10.15252/embj.2021110439
PMCID:
PMC9379545
AbstractArticlePDF–20M
9.
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH)
Xinzhi Li, Kaixin Ding, Xueying Li, Bingchuan Yuan, Yuqin Wang, Zhicheng Yao, Shuaikang Wang, He Huang, Bolin Xu, Liwei Xie, Tuo Deng, Xiao-wei Chen, Zheng Chen
Nat Commun. 2022; 13: 4549. Published online 2022 Aug 4. doi: 10.1038/s41467-022-32163-w
PMCID:
PMC9352699
AbstractArticlePDF–5.0M
10.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
11.
Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration
Shu-Juan Xie, Hang Lei, Bing Yang, Li-Ting Diao, Jian-You Liao, Jie-Hua He, Shuang Tao, Yan-Xia Hu, Ya-Rui Hou, Yu-Jia Sun, Yan-Wen Peng, Qi Zhang, Zhen-Dong Xiao
Front Cell Dev Biol. 2021; 9: 744171. Published online 2021 Oct 1. doi: 10.3389/fcell.2021.744171
PMCID:
PMC8517268
AbstractArticlePDF–6.4M
12.
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation
Kai P. Hoefig, Alexander Reim, Christian Gallus, Elaine H. Wong, Gesine Behrens, Christine Conrad, Meng Xu, Lisa Kifinger, Taku Ito-Kureha, Kyra A. Y. Defourny, Arie Geerlof, Josef Mautner, Stefanie M. Hauck, Dirk Baumjohann, Regina Feederle, Matthias Mann, Michael Wierer, Elke Glasmacher, Vigo Heissmeyer
Nat Commun. 2021; 12: 5208. Published online 2021 Sep 1. doi: 10.1038/s41467-021-25345-5
PMCID:
PMC8410761
AbstractArticlePDF–16M
13.
WTAP Function in Sertoli Cells Is Essential for Sustaining the Spermatogonial Stem Cell Niche
Gong-Xue Jia, Zhen Lin, Rong-Ge Yan, Guo-Wen Wang, Xiao-Na Zhang, Cen Li, Ming-Han Tong, Qi-En Yang
Stem Cell Reports. 2020 Oct 13; 15(4): 968–982. Published online 2020 Oct 13. doi: 10.1016/j.stemcr.2020.09.001
PMCID:
PMC7566211
AbstractArticlePDF–7.0M
14.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
15.
The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis
Masatoshi Kobayashi, Mitsuru Ohsugi, Takayoshi Sasako, Motoharu Awazawa, Toshihiro Umehara, Aya Iwane, Naoki Kobayashi, Yukiko Okazaki, Naoto Kubota, Ryo Suzuki, Hironori Waki, Keiko Horiuchi, Takao Hamakubo, Tatsuhiko Kodama, Seiichiro Aoe, Kazuyuki Tobe, Takashi Kadowaki, Kohjiro Ueki
Mol Cell Biol. 2018 Aug 15; 38(16): e00116-18. Prepublished online 2018 Jun 4. Published online 2018 Jul 30. doi: 10.1128/MCB.00116-18
PMCID:
PMC6066751
AbstractArticlePDF–6.2M
16.
Zc3h13 regulates nuclear RNA m6A methylation and mouse embryonic stem cell self-renewal
Jing Wen, Ruitu Lv, Honghui Ma, Hongjie Shen, Chenxi He, Jiahua Wang, Fangfang Jiao, Hang Liu, Pengyuan Yang, Li Tan, Fei Lan, Yujiang Geno Shi, Chuan He, Yang Shi, Jianbo Diao
Mol Cell. Author manuscript; available in PMC 2019 Mar 15.
Published in final edited form as: Mol Cell. 2018 Mar 15; 69(6): 1028–1038.e6. doi: 10.1016/j.molcel.2018.02.015
PMCID:
PMC5858226
AbstractArticlePDF–1.6M
17.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
18.
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
Benoit Moindrot, Andrea Cerase, Heather Coker, Osamu Masui, Anne Grijzenhout, Greta Pintacuda, Lothar Schermelleh, Tatyana B. Nesterova, Neil Brockdorff
Cell Rep. 2015 Jul 28; 12(4): 562–572. Published online 2015 Jul 16. doi: 10.1016/j.celrep.2015.06.053
PMCID:
PMC4534822
AbstractArticlePDF–4.2M
19.
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPa N-terminal leukemia
Florian Grebien, Masoud Vedadi, Matthäus Getlik, Roberto Giambruno, Amit Grover, Roberto Avellino, Anna Skucha, Sarah Vittori, Ekaterina Kuznetsova, David Smil, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Matthieu Schapira, Hong Wu, Aiping Dong, Guillermo Senisterra, Alexey Stukalov, Kilian V. M. Huber, Andreas Schönegger, Richard Marcellus, Martin Bilban, Christoph Bock, Peter J. Brown, Johannes Zuber, Keiryn L. Bennett, Rima Al-awar, Ruud Delwel, Claus Nerlov, Cheryl H. Arrowsmith, Giulio Superti-Furga
Nat Chem Biol. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Chem Biol. 2015 Aug; 11(8): 571–578. Published online 2015 Jul 13. doi: 10.1038/nchembio.1859
PMCID:
PMC4511833
AbstractArticlePDF–2.2M
20.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M

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