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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
3.
Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons
Nuria Ruiz-Reig, Dario García-Sánchez, Olivier Schakman, Philippe Gailly, Fadel Tissir
Front Mol Neurosci. 2022; 15: 1110986. Published online 2023 Jan 17. doi: 10.3389/fnmol.2022.1110986
PMCID:
PMC9887042
AbstractArticlePDF–1.6M
4.
KIF2A deficiency causes early-onset neurodegeneration
Nuria Ruiz-Reig, Georges Chehade, Janne Hakanen, Mohamed Aittaleb, Keimpe Wierda, Joris De Wit, Laurent Nguyen, Philippe Gailly, Fadel Tissir
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2209714119. Published online 2022 Nov 7. doi: 10.1073/pnas.2209714119
PMCID:
PMC9674219
AbstractArticlePDF–3.8M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
6.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
7.
KIF3A accelerates KIF3C within the kinesin-2 heterodimer to generate symmetrical phosphate release rates for each processive step
Sean M. Quinn, Troy Vargason, Nilisha Pokhrel, Edwin Antony, Juergen Hahn, Susan P. Gilbert
J Biol Chem. 2021 Jan-Jun; 296: 100020. Published online 2020 Nov 22. doi: 10.1074/jbc.RA120.015272
PMCID:
PMC7948976
AbstractArticlePDF–1.7M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny
Johan G Gilet, Ekaterina L Ivanova, Daria Trofimova, Gabrielle Rudolf, Hamid Meziane, Loic Broix, Nathalie Drouot, Jeremie Courraud, Valerie Skory, Paul Voulleminot, Maria Osipenko, Nadia Bahi-Buisson, Binnaz Yalcin, Marie-Christine Birling, Maria-Victoria Hinckelmann, Benjamin H Kwok, John S Allingham, Jamel Chelly
Hum Mol Genet. 2020 Mar 27; 29(5): 766–784. Published online 2020 Jan 10. doi: 10.1093/hmg/ddz316
PMCID:
PMC7104682
AbstractArticlePDF–2.6M
10.
Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
Wei Zhang, Si-Lu Yang, Mei Yang, Stephanie Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lu, Bruce E. Herring, Ming-Lei Guo, Shilpa Buch, Zhen Zhao, Jian Xu, Zhipeng Lu, Jian-Fu Chen
Nat Commun. 2019; 10: 2612. Published online 2019 Jun 13. doi: 10.1038/s41467-019-10497-2
PMCID:
PMC6565620
AbstractArticlePDF–6.1M
11.
Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex
Wenyu Ding, Qian Wu, Le Sun, Na Clara Pan, Xiaoqun Wang
J Neurosci. 2019 Mar 13; 39(11): 1994–2010. doi: 10.1523/JNEUROSCI.1849-18.2018
PMCID:
PMC6507096
AbstractArticlePDF–24M
12.
Kinesin-2 heterodimerization alters entry into a processive run along the microtubule but not stepping within the run
Sean M. Quinn, Daniel P. Howsmon, Juergen Hahn, Susan P. Gilbert
J Biol Chem. 2018 Aug 31; 293(35): 13389–13400. Published online 2018 Jul 10. doi: 10.1074/jbc.RA118.002767
PMCID:
PMC6120217
AbstractArticlePDF–1.7M
13.
KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring
Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G Chaudhary, Mohammed H Al-Qahtani, Nobutaka Hirokawa
eLife. 2018; 7: e30935. Published online 2018 Jan 9. doi: 10.7554/eLife.30935
PMCID:
PMC5811213
AbstractArticlePDF–6.1M
14.
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex
Sara Bizzotto, Ana Uzquiano, Florent Dingli, Dmitry Ershov, Anne Houllier, Guillaume Arras, Mark Richards, Damarys Loew, Nicolas Minc, Alexandre Croquelois, Anne Houdusse, Fiona Francis
Sci Rep. 2017; 7: 17308. Published online 2017 Dec 11. doi: 10.1038/s41598-017-15253-4
PMCID:
PMC5725533
AbstractArticlePDF–2.3M
15.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
16.
Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction
Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II
Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076
PMCID:
PMC5467389
AbstractArticlePDF–3.2M
17.
Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a
Dong Sun, Xue Zhou, Hua-Li Yu, Xiao-Xiao He, Wei-Xiang Guo, Wen-Cheng Xiong, Xiao-Juan Zhu
PLoS One. 2017; 12(6): e0179047. Published online 2017 Jun 7. doi: 10.1371/journal.pone.0179047
PMCID:
PMC5462413
AbstractArticlePDF–36M
18.
Cell Type-specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex
Xiaochang Zhang, Ming Hui Chen, Xuebing Wu, Andrew Kodani, Jean Fan, Ryan Doan, Manabu Ozawa, Jacqueline Ma, Nobuaki Yoshida, Jeremy F. Reiter, Douglas L. Black, Peter V. Kharchenko, Phillip A. Sharp, Christopher A. Walsh
Cell. Author manuscript; available in PMC 2017 Jan 20.
Published in final edited form as: Cell. 2016 Aug 25; 166(5): 1147–1162.e15. doi: 10.1016/j.cell.2016.07.025
PMCID:
PMC5248659
AbstractArticlePDF–3.7M
19.
KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte
Ming-Huang Chen, Yu Liu, Ya-Long Wang, Rui Liu, Bai-Hui Xu, Fei Zhang, Fei-Ping Li, Lin Xu, Yan-Hong Lin, Shu-Wen He, Bao-Qiong Liao, Xian-Pei Fu, Xiao-Xue Wang, Xiang-Jun Yang, Hai-Long Wang
Sci Rep. 2016; 6: 39337. Published online 2016 Dec 19. doi: 10.1038/srep39337
PMCID:
PMC5171862
AbstractArticlePDF–1.4M
20.
Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes
Zi-Yun Yi, Xue-Shan Ma, Qiu-Xia Liang, Teng Zhang, Zhao-Yang Xu, Tie-Gang Meng, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Qing-Yuan Sun, Song Quan
Sci Rep. 2016; 6: 38574. Published online 2016 Dec 19. doi: 10.1038/srep38574
PMCID:
PMC5171826
AbstractArticlePDF–1.8M

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