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Items: 1 to 20 of 246

1.
Production of IL-35 by Bregs is mediated through binding of BATF-IRF-4-IRF-8 complex to il12a and ebi3 promoter elements
Cheng-Rong Yu, Jin Kyeong Choi, Anita N. Uche, Charles E. Egwuagu
J Leukoc Biol. Author manuscript; available in PMC 2024 Jul 31.
Published in final edited form as: J Leukoc Biol. 2018 Dec; 104(6): 1147–1157. Published online 2018 Aug 17. doi: 10.1002/JLB.3A0218-071RRR
PMCID:
PMC11290588
AbstractArticlePDF–1.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
IL-12p40 is essential but not sufficient for Francisella tularensis LVS clearance in chronically infected mice
Lara R. Mittereder, Jonathan Swoboda, Roberto De Pascalis, Karen L. Elkins
PLoS One. 2023; 18(3): e0283161. Published online 2023 Mar 27. doi: 10.1371/journal.pone.0283161
PMCID:
PMC10042368
AbstractArticlePDF–1.1M
4.
IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression
Umesh Bhattarai, Xiaochen He, Rui Xu, Xiaoguang Liu, Lihong Pan, Yuxiang Sun, Jian-Xiong Chen, Yingjie Chen
Front Immunol. 2023; 14: 1105664. Published online 2023 Feb 13. doi: 10.3389/fimmu.2023.1105664
PMCID:
PMC9969090
AbstractArticlePDF–13M
5.
STING-induced regulatory B cells compromise NK function in cancer immunity
Sirui Li, Bhalchandra Mirlekar, Brandon M. Johnson, W. June Brickey, John A. Wrobel, Na Yang, Dingka Song, Sarah Entwistle, Xianming Tan, Meng Deng, Ya Cui, Wei Li, Benjamin G. Vincent, Michael Gale, Jr., Yuliya Pylayeva-Gupta, Jenny P.-Y. Ting
Nature. Author manuscript; available in PMC 2023 Apr 5.
Published in final edited form as: Nature. 2022 Oct; 610(7931): 373–380. Published online 2022 Oct 5. doi: 10.1038/s41586-022-05254-3
PMCID:
PMC9875944
AbstractArticlePDF–3.1M
6.
cDC1-derived IL-27 regulates small intestinal CD4+ T cell homeostasis in mice
Fatemeh Ahmadi, Fredrik Junghus, Christian Ashworth, Amanda Lappalainen, Urs Mörbe, Knut Kotarsky, William W. Agace
J Exp Med. 2023 Mar 6; 220(3): e20221090. Published online 2022 Dec 14. doi: 10.1084/jem.20221090
PMCID:
PMC9754766
AbstractArticlePDF–4.8M
7.
Hassall’s corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus
Jianwei Wang, Miho Sekai, Takeshi Matsui, Yosuke Fujii, Mitsuru Matsumoto, Osamu Takeuchi, Nagahiro Minato, Yoko Hamazaki
Int Immunol. 2019 Mar; 31(3): 127–139. Published online 2018 Dec 10. doi: 10.1093/intimm/dxy073
PMCID:
PMC9271218
AbstractArticlePDF–3.0M
8.
A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors
Diyuan Xue, Benjamin Moon, Jing Liao, Jingya Guo, Zhuangzhi Zou, Yanfei Han, Shuaishuai Cao, Yang Wang, Yang-Xin Fu, Hua Peng
Sci Immunol. Author manuscript; available in PMC 2022 Jul 7.
Published in final edited form as: Sci Immunol. 2022 Jan 7; 7(67): eabi6899. Published online 2022 Jan 7. doi: 10.1126/sciimmunol.abi6899
PMCID:
PMC9009736
AbstractArticlePDF–1.4M
9.
Non-autophagy Role of Atg5 and NBR1 in Unconventional Secretion of IL-12 Prevents Gut Dysbiosis and Inflammation
Seth D Merkley, Samuel M Goodfellow, Yan Guo, Zoe E R Wilton, Janie R Byrum, Kurt C Schwalm, Darrell L Dinwiddie, Rama R Gullapalli, Vojo Deretic, Anthony Jimenez Hernandez, Steven B Bradfute, Julie G In, Eliseo F Castillo
J Crohns Colitis. 2022 Feb; 16(2): 259–274. Published online 2021 Aug 10. doi: 10.1093/ecco-jcc/jjab144
PMCID:
PMC8864635
AbstractArticlePDF–3.5M
10.
GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation
Kamaljeet Kaur, Holly Bachus, Crystal Lewis, Amber M. Papillion, Alexander F. Rosenberg, André Ballesteros-Tato, Beatriz León
Cell Rep. Author manuscript; available in PMC 2022 Jan 14.
Published in final edited form as: Cell Rep. 2021 Dec 28; 37(13): 110178. doi: 10.1016/j.celrep.2021.110178
PMCID:
PMC8759241
AbstractArticlePDF–2.6M
11.
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo
Allison N. Gerber, Kaveh Abdi, Nevil J. Singh
Cell Rep. Author manuscript; available in PMC 2021 Nov 5.
Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109816. doi: 10.1016/j.celrep.2021.109816
PMCID:
PMC8569637
AbstractArticlePDF–1.6M
12.
IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms
Ying Shao, William Y. Yang, Fatma Saaoud, Charles Drummer, IV, Yu Sun, Keman Xu, Yifan Lu, Huimin Shan, Ethan M. Shevach, Xiaohua Jiang, Hong Wang, Xiaofeng Yang
JCI Insight. 2021 Oct 8; 6(19): e152511. Published online 2021 Oct 8. doi: 10.1172/jci.insight.152511
PMCID:
PMC8525592
AbstractArticlePDF–2.6M
13.
A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis
Chun-Hao Hung, Tung-Liang Lee, Anna Yu-Szu Huang, Kang-Chung Yang, Yu-Chiau Shyu, Shau-Ching Wen, Mu-Jie Lu, Shinsheng Yuan, Che-Kun James Shen
Int J Mol Sci. 2021 Aug; 22(15): 8024. Published online 2021 Jul 27. doi: 10.3390/ijms22158024
PMCID:
PMC8347936
AbstractArticlePDF–4.4M
14.
Silencing IL12p35 Promotes Angiotensin II-Mediated Abdominal Aortic Aneurysm through Activating the STAT4 Pathway
Lanlan Wang, Chengyun Hu, Yongfei Dong, Feibiao Dai, Yongxia Xu, Yumeng Dai, Lijie Shao, Defa Zhu
Mediators Inflamm. 2021; 2021: 9450843. Published online 2021 Jul 27. doi: 10.1155/2021/9450843
PMCID:
PMC8331298
AbstractArticlePDF–1.8M
15.
Targeted cytokine delivery: cell therapy to remodel the pre-metastatic niche
Michael A. Morgan, Lucas Lange, Axel Schambach
Signal Transduct Target Ther. 2021; 6: 282. Published online 2021 Jul 25. doi: 10.1038/s41392-021-00694-1
PMCID:
PMC8310887
ArticlePDF–545K
16.
Nanoparticle-mediated tumor cell expression of mIL-12 via systemic gene delivery treats syngeneic models of murine lung cancers
Hye-Hyun Ahn, Christine Carrington, Yizong Hu, Heng-wen Liu, Christy Ng, Hwanhee Nam, Andrew Park, Catherine Stace, Will West, Hai-Quan Mao, Martin G. Pomper, Christopher G. Ullman, Il Minn
Sci Rep. 2021; 11: 9733. Published online 2021 May 6. doi: 10.1038/s41598-021-89124-4
PMCID:
PMC8102550
AbstractArticlePDF–1.3M
17.
Interleukin-35 Is Involved in Angiogenesis/Bone Remodeling Coupling Through T Helper 17/Interleukin-17 Axis
Hui Zhang, Yuxuan Li, Lin Yuan, Lutian Yao, Jie Yang, Liping Xia, Hui Shen, Jing Lu
Front Endocrinol (Lausanne) 2021; 12: 642676. Published online 2021 Apr 16. doi: 10.3389/fendo.2021.642676
PMCID:
PMC8085552
AbstractArticlePDF–4.8M
18.
Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues
Dominika W. Gajdasik, Fabrina Gaspal, Emily E. Halford, Remi Fiancette, Emma E. Dutton, Claire Willis, Timo Rückert, Chiara Romagnani, Audrey Gerard, Sarah L. Bevington, Andrew S. MacDonald, Marina Botto, Timothy Vyse, David R. Withers
Nat Commun. 2020; 11: 3421. Published online 2020 Jul 9. doi: 10.1038/s41467-020-17293-3
PMCID:
PMC7347572
AbstractArticlePDF–2.6M
19.
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state
Takeshi Kawabe, Jaeu Yi, Akihisa Kawajiri, Kerry Hilligan, Difeng Fang, Naoto Ishii, Hidehiro Yamane, Jinfang Zhu, Dragana Jankovic, Kwang Soon Kim, Giorgio Trinchieri, Alan Sher
Nat Commun. 2020; 11: 3366. Published online 2020 Jul 6. doi: 10.1038/s41467-020-17136-1
Correction in:
Nat Commun. 2020; 11: 4624.
PMCID:
PMC7338451
AbstractArticlePDF–3.5M
20.
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation
Takuma Misawa, Jeffrey A. SoRelle, Jin Huk Choi, Tao Yue, Kuan-wen Wang, William McAlpine, Jianhui Wang, Aijie Liu, Koichi Tabeta, Emre Turer, Bret Evers, Evan Nair-Gill, Subhajit Poddar, Lijing Su, Feiya Ou, Liyang Yu, Jamie Russell, Sara Ludwig, Xiaoming Zhan, Sara Hildebrand, Xiaohong Li, Miao Tang, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler
Sci Immunol. Author manuscript; available in PMC 2020 Jul 24.
Published in final edited form as: Sci Immunol. 2020 Jan 24; 5(43): eaaz0085. doi: 10.1126/sciimmunol.aaz0085
PMCID:
PMC7278039
AbstractArticlePDF–1.7M

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