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Items: 1 to 20 of 394

1.
Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy
Amy-Jayne Hutchings, Bita Hambrecht, Alexander Veh, Neha Jadhav Giridhar, Abdolhossein Zare, Christina Angerer, Thorben Ohnesorge, Maren Schenke, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Jared Sterneckert, Susanne Petri, Bettina Seeger, Michael Briese, Christian Stigloher, Thorsten Bischler, Andreas Hermann, Markus Damme, Michael Sendtner, Patrick Lüningschrör
Nat Commun. 2024; 15: 8622. Published online 2024 Oct 4. doi: 10.1038/s41467-024-52875-5
PMCID:
PMC11452647
AbstractArticlePDF–4.5M
2.
Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates demetalation with pathology
Oliver J. Hale, Tyler R. Wells, Richard J. Mead, Helen J. Cooper
Nat Commun. 2024; 15: 6518. Published online 2024 Aug 8. doi: 10.1038/s41467-024-50514-7
PMCID:
PMC11310518
AbstractArticlePDF–3.5M
3.
Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally
Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariotti
Eur J Histochem. 2024 Jun 27; 68(3): 4040. Published online 2024 Jul 4. doi: 10.4081/ejh.2024.4040
PMCID:
PMC11256976
AbstractArticlePDF–7.8M
4.
Extracellular wildtype and mutant SOD1 induces ER–Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells
Vinod Sundaramoorthy, Adam K. Walker, Justin Yerbury, Kai Ying Soo, Manal A. Farg, Vy Hoang, Rafaa Zeineddine, Damian Spencer, Julie D. Atkin
Cell Mol Life Sci. 2013 Nov; 70(21): 4181–4195. Published online 2013 Jun 14. doi: 10.1007/s00018-013-1385-2
PMCID:
PMC11113712
AbstractArticlePDF–1.7M
5.
Selective removal of misfolded SOD1 delays disease onset in a mouse model of amyotrophic lateral sclerosis
Teng Guan, Ting Zhou, Xiaosha Zhang, Ying Guo, Chaoxian Yang, Justin Lin, Jiasi Vicky Zhang, Yongquan Cheng, Hassan Marzban, Yu Tian Wang, Jiming Kong
Cell Mol Life Sci. 2023 Oct; 80(10): 304. Published online 2023 Sep 26. doi: 10.1007/s00018-023-04956-9
PMCID:
PMC11072549
AbstractArticlePDF–7.2M
6.
VEGF expression disparities in brainstem motor neurons of the SOD1G93A ALS model: Correlations with neuronal vulnerability
Silvia Silva-Hucha, M. Estrella Fernández de Sevilla, Kirsty M. Humphreys, Fiona E. Benson, Jaime M. Franco, David Pozo, Angel M. Pastor, Sara Morcuende
Neurotherapeutics. 2024 Apr; 21(3): e00340. Published online 2024 Mar 11. doi: 10.1016/j.neurot.2024.e00340
PMCID:
PMC11070718
AbstractArticlePDF–3.9M
7.
Novel insights into RAGE signaling pathways during the progression of amyotrophic lateral sclerosis in RAGE-deficient SOD1 G93A mice
Natalia Nowicka, Kamila Zglejc-Waszak, Judyta Juranek, Agnieszka Korytko, Krzysztof Wąsowicz, Małgorzata Chmielewska-Krzesińska, Joanna Wojtkiewicz
PLoS One. 2024; 19(3): e0299567. Published online 2024 Mar 8. doi: 10.1371/journal.pone.0299567
PMCID:
PMC10923448
AbstractArticlePDF–2.4M
8.
Oxidized SOD1 accelerates cellular senescence in neural stem cells
Teng Guan, Ying Guo, Ting Zhou, Qiang Yu, Jingyi Sun, Baoliang Sun, Guohui Zhang, Jiming Kong
Stem Cell Res Ther. 2024; 15: 55. Published online 2024 Feb 27. doi: 10.1186/s13287-024-03669-5
PMCID:
PMC10900543
AbstractArticlePDF–4.6M
9.
Spinal cord abnormal autophagy and mitochondria energy metabolism are modified by swim training in SOD1-G93A mice
Katarzyna Patrycja Dzik, Damian Józef Flis, Katarzyna Barbara Kaczor-Keller, Zofia Kinga Bytowska, Mateusz Jakub Karnia, Wiesław Ziółkowski, Jan Jacek Kaczor
J Mol Med (Berl) 2024; 102(3): 379–390. Published online 2024 Jan 10. doi: 10.1007/s00109-023-02410-8
PMCID:
PMC10879285
AbstractArticlePDF–3.8M
10.
Leptin haploinsufficiency exerts sex-dependent partial protection in SOD1G93A mice by reducing inflammatory pathways in the adipose tissue
Luis C. Fernández-Beltrán, Zeinab Ali, Angélica Larrad-Sanz, Juan I. Lopez-Carbonero, Juan M. Godoy-Corchuelo, Irene Jimenez-Coca, Irene Garcia-Toledo, Liz Bentley, Ulises Gomez-Pinedo, Jordi A. Matias-Guiu, Maria Jose Gil-Moreno, Jorge Matias-Guiu, Silvia Corrochano
Sci Rep. 2024; 14: 2671. Published online 2024 Feb 1. doi: 10.1038/s41598-024-52439-z
PMCID:
PMC10834470
AbstractArticlePDF–5.7M
11.
Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS
Md Amin Hossain, Richa Sarin, Daniel P. Donnelly, Brandon C. Miller, Alexandra Weiss, Luke McAlary, Svetlana V. Antonyuk, Joseph P. Salisbury, Jakal Amin, Jeremy B. Conway, Samantha S. Watson, Jenifer N. Winters, Yu Xu, Novera Alam, Rutali R. Brahme, Haneyeh Shahbazian, Durgalakshmi Sivasankar, Swathi Padmakumar, Aziza Sattarova, Aparna C. Ponmudiyan, Tanvi Gawde, David E. Verrill, Wensheng Yang, Sunanda Kannapadi, Leigh D. Plant, Jared R. Auclair, Lee Makowski, Gregory A. Petsko, Dagmar Ringe, Nathalie Y. R. Agar, David J. Greenblatt, Mary Jo Ondrechen, Yunqiu Chen, Justin J. Yerbury, Roman Manetsch, S. Samar Hasnain, Robert H. Brown, Jr., Jeffrey N. Agar
PLoS Biol. 2024 Jan; 22(1): e3002462. Published online 2024 Jan 30. doi: 10.1371/journal.pbio.3002462
PMCID:
PMC10826971
AbstractArticlePDF–5.0M
12.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
13.
ALS-linked SOD1 mutations impair mitochondrial-derived vesicle formation and accelerate aging
Ying Guo, Teng Guan, Qiang Yu, Nitesh Sanghai, Kashfia Shafiq, Meiyu Li, Xin Jiao, Donghui Na, Guohui Zhang, Jiming Kong
Redox Biol. 2024 Feb; 69: 102972. Published online 2023 Nov 24. doi: 10.1016/j.redox.2023.102972
PMCID:
PMC10746562
AbstractArticlePDF–11M
14.
Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice
Abhirami K. Iyer, Kathleen M. Schoch, Anthony Verbeck, Grant Galasso, Hao Chen, Sarah Smith, Anna Oldenborg, Timothy M. Miller, Celeste M. Karch, Azad Bonni
PLoS One. 2023; 18(11): e0294731. Published online 2023 Nov 28. doi: 10.1371/journal.pone.0294731
PMCID:
PMC10683999
AbstractArticlePDF–3.0M
15.
The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model
Hui Zhao, Ronald J. Wong, David K. Stevenson
PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185
PMCID:
PMC10637699
AbstractArticlePDF–3.6M
16.
AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia
Lingying Tong, Burcak Ozes, Kyle Moss, Morgan Myers, Alicia Ridgley, Zarife Sahenk
J Cachexia Sarcopenia Muscle. 2023 Oct; 14(5): 2204–2215. Published online 2023 Aug 8. doi: 10.1002/jcsm.13303
PMCID:
PMC10570084
AbstractArticlePDF–3.6M
17.
Maintenance of subsynaptic myonuclei number is not driven by neural input
Lloyd P. Ruiz, Peter C. Macpherson, Susan V. Brooks
Front Physiol. 2023; 14: 1266950. Published online 2023 Sep 26. doi: 10.3389/fphys.2023.1266950
PMCID:
PMC10562629
AbstractArticlePDF–2.7M
18.
Multiple Factors Influence the Incubation Period of ALS Prion-like Transmission in SOD1 Transgenic Mice
Jacob I. Ayers, Guilian Xu, Qing Lu, Kristy Dillon, Susan Fromholt, David R. Borchelt
Viruses. 2023 Sep; 15(9): 1819. Published online 2023 Aug 26. doi: 10.3390/v15091819
PMCID:
PMC10534885
AbstractArticlePDF–4.8M
19.
CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A
Valentina La Cognata, Agata Grazia D’Amico, Grazia Maugeri, Giovanna Morello, Maria Guarnaccia, Benedetta Magrì, Eleonora Aronica, Velia D’Agata, Sebastiano Cavallaro
Cells. 2023 Jul; 12(14): 1813. Published online 2023 Jul 9. doi: 10.3390/cells12141813
PMCID:
PMC10377984
AbstractArticlePDF–7.7M
20.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M

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