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Select item 114129081.

PAK3 activation promotes the tangential to radial migration switch of cortical interneurons by increasing leading process dynamics and disrupting cell polarity

Lucie Viou, Melody Atkins, Véronique Rousseau, Pierre Launay, Justine Masson, Clarisse Pace, Fujio Murakami, Jean-Vianney Barnier, Christine Métin

Mol Psychiatry. 2024; 29(8): 2296–2307. Published online 2024 Mar 7. doi: 10.1038/s41380-024-02483-y

PMCID:: PMC11412908

Abstract Article PDF–7.1M

Select item 111783582.

Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination

Ruonan Zhao, Emma L Moore, Madelaine M Gogol, Jay R Unruh, Zulin Yu, Allison R Scott, Yan Wang, Naresh K Rajendran, Paul A Trainor

eLife. 2024; 13: RP92844. Published online 2024 Jun 14. doi: 10.7554/eLife.92844

PMCID:: PMC11178358

Abstract Article PDF–9.6M

Select item 110681083.

PAK2 is necessary for myelination in the peripheral nervous system

Bo Hu, Daniel Moiseev, Isabella Schena, Bulat Faezov, Roland Dunbrack, Jonathan Chernoff, Jun Li

Brain. 2024 May; 147(5): 1809–1821. Published online 2023 Dec 11. doi: 10.1093/brain/awad413

PMCID:: PMC11068108

Abstract Article PDF–1.6M

Select item 110452214.

Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

Simona Bolamperti, Hiroaki Saito, Sarah Heerdmann, Eric Hesse, Hanna Taipaleenmäki

eLife. 2024; 13: RP94265. Published online 2024 Apr 25. doi: 10.7554/eLife.94265

PMCID:: PMC11045221

Abstract Article PDF–17M

Select item 107461435.

PAK3 downregulation induces cognitive impairment following cranial irradiation

Haksoo Lee, Hyunkoo Kang, Changjong Moon, BuHyun Youn

eLife. 2023; 12: RP89221. Published online 2023 Dec 22. doi: 10.7554/eLife.89221

PMCID:: PMC10746143

Abstract Article PDF–6.9M

Select item 90166196.

SIRT1 regulates cardiomyocyte alignment during maturation

Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K. Janoshazi, David C. Fargo, Xiaoling Li

J Cell Sci. 2022 Apr 1; 135(7): jcs259076. Published online 2022 Apr 1. doi: 10.1242/jcs.259076

PMCID:: PMC9016619

Abstract Article

Select item 86161037.

Disruption of PAK3 Signaling in Social Interaction Induced cFos Positive Cells Impairs Social Recognition Memory

Susan Zhou, Zhengping Jia

Cells. 2021 Nov; 10(11): 3010. Published online 2021 Nov 4. doi: 10.3390/cells10113010

PMCID:: PMC8616103

Abstract Article PDF–6.5M

Select item 83578888.

Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

Xiaohong Tan, Lu Tong, Lin Li, Jinjin Xu, Shaofang Xie, Lei Ji, Junjiang Fu, Qingwu Liu, Shihui Shen, Yun Liu, Yanhui Xiao, Feiran Gao, Robb E. Moses, Nabeel Bardeesy, Yanxiao Wang, Jishuai Zhang, Longying Tang, Lei Li, Kwok-kin Wong, Dianwen Song, Xiao Yang, Jian Liu, Xiaotao Li

Nat Commun. 2021; 12: 4853. Published online 2021 Aug 11. doi: 10.1038/s41467-021-24898-9

PMCID:: PMC8357888

Abstract Article PDF–8.9M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 782173111.

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons

Kazuhiro Hada, Bolati Wulaer, Taku Nagai, Norimichi Itoh, Masahito Sawahata, Akira Sobue, Hiroyuki Mizoguchi, Daisuke Mori, Itaru Kushima, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada

Mol Brain. 2021; 14: 21. Published online 2021 Jan 22. doi: 10.1186/s13041-021-00735-4

PMCID:: PMC7821731

Abstract Article PDF–2.8M

Select item 688915512.

Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex

Jie Liu, Yanfeng Liu, Jiaxiang Shao, Yisheng Li, Lixia Qin, Hailian Shen, Yunli Xie, Weiliang Xia, Wei-Qiang Gao

Cell Death Differ. 2019 Nov; 26(11): 2479–2492. Published online 2019 Mar 11. doi: 10.1038/s41418-019-0314-9

PMCID:: PMC6889155

Abstract Article PDF–6.3M

Select item 673020213.

The Mental Retardation Protein PAK3 Contributes to Synapse Formation and Plasticity in Hippocampus

Bernadett Boda, Stefano Alberi, Irina Nikonenko, Roxanne Node-Langlois, Pascal Jourdain, Marlyse Moosmayer, Lorena Parisi-Jourdain, Dominique Muller

J Neurosci. 2004 Dec 1; 24(48): 10816–10825. doi: 10.1523/JNEUROSCI.2931-04.2004

PMCID:: PMC6730202

Abstract Article PDF–563K

Select item 672542014.

Abnormal Long-Lasting Synaptic Plasticity and Cognition in Mice Lacking the Mental Retardation Gene Pak3

Jinsong Meng, Yanghong Meng, Amanda Hanna, Christopher Janus, Zhengping Jia

J Neurosci. 2005 Jul 13; 25(28): 6641–6650. doi: 10.1523/JNEUROSCI.0028-05.2005

PMCID:: PMC6725420

Abstract Article PDF–619K

Select item 667024415.

Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation

Cheng-Yi Yang, Ting-Hsuan Yu, Wan-Ling Wen, Pin Ling, Kuei-Sen Hsu

J Neurosci. 2019 Jun 19; 39(25): 4959–4975. doi: 10.1523/JNEUROSCI.2395-18.2019

PMCID:: PMC6670244

Abstract Article PDF–3.4M

Select item 662106916.

Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

Aline Dubos, Gaelle Combeau, Yann Bernardinelli, Jean-Vianney Barnier, Oliver Hartley, Hubert Gaertner, Bernadett Boda, Dominique Muller

J Neurosci. 2012 Jan 11; 32(2): 519–527. doi: 10.1523/JNEUROSCI.3252-11.2012

PMCID:: PMC6621069

Abstract Article PDF–1.8M

Select item 617601017.

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice

Chengwen Zhu, Cheng Cheng, Yanfei Wang, Waqas Muhammad, Shuang Liu, Weijie Zhu, Buwei Shao, Zhong Zhang, Xiaoqian Yan, Qingqing He, Zhengrong Xu, Chenjie Yu, Xiaoyun Qian, Ling Lu, Shasha Zhang, Yuan Zhang, Wei Xiong, Xia Gao, Zhigang Xu, Renjie Chai

Front Mol Neurosci. 2018; 11: 362. Published online 2018 Oct 2. doi: 10.3389/fnmol.2018.00362

PMCID:: PMC6176010

Abstract Article PDF–7.8M

Select item 607781418.

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1

Vitaliy V Bondar, Carolyn J Adamski, Tarik S Onur, Qiumin Tan, Li Wang, Javier Diaz-Garcia, Jeehye Park, Harry T Orr, Juan Botas, Huda Y Zoghbi

Hum Mol Genet. 2018 Aug 15; 27(16): 2863–2873. Published online 2018 May 30. doi: 10.1093/hmg/ddy200

PMCID:: PMC6077814

Abstract Article PDF–1.1M

Select item 564508219.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 492123720.

Dlx transcription factors promote migration through repression of axon and dendrite growth

Inma Cobos, Ugo Borello, John L.R. Rubenstein

Neuron. Author manuscript; available in PMC 2016 Jun 26.

Published in final edited form as: Neuron. 2007 Jun 21; 54(6): 873–888. doi: 10.1016/j.neuron.2007.05.024

PMCID:: PMC4921237

Abstract Article PDF–1.2M

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