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Select item 108057901.

Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity

Fabio Zanini, Xibing Che, Nina E. Suresh, Carsten Knutsen, Paula Klavina, Yike Xie, Racquel Domingo-Gonzalez, Min Liu, Alexander Kum, Robert C. Jones, Stephen R. Quake, Cristina M. Alvira, David N. Cornfield

Sci Rep. 2024; 14: 2033. Published online 2024 Jan 23. doi: 10.1038/s41598-023-50717-w

PMCID:: PMC10805790

Abstract Article PDF–2.9M

Select item 99682972.

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee

Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y

PMCID:: PMC9968297

Abstract Article PDF–4.4M

Select item 73344693.

Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus

Laure Delavallée, Navrita Mathiah, Lauriane Cabon, Aurélien Mazeraud, Marie-Noelle Brunelle-Navas, Leticia K. Lerner, Mariana Tannoury, Alexandre Prola, Raquel Moreno-Loshuertos, Mathieu Baritaud, Laura Vela, Kevin Garbin, Delphine Garnier, Christophe Lemaire, Francina Langa-Vives, Martine Cohen-Salmon, Patricio Fernández-Silva, Fabrice Chrétien, Isabelle Migeotte, Santos A. Susin

Mol Metab. 2020 Oct; 40: 101027. Published online 2020 May 30. doi: 10.1016/j.molmet.2020.101027

PMCID:: PMC7334469

Abstract Article PDF–3.5M

Select item 63776334.

Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy

María Cristina Estañ, Elisa Fernández-Núñez, Maha S. Zaki, María Isabel Esteban, Sandra Donkervoort, Cynthia Hawkins, José A. Caparros-Martin, Dimah Saade, Ying Hu, Véronique Bolduc, Katherine Ru-Yui Chao, Julián Nevado, Ana Lamuedra, Raquel Largo, Gabriel Herrero-Beaumont, Javier Regadera, Concepción Hernandez-Chico, Eduardo F. Tizzano, Victor Martinez-Glez, Jaime J. Carvajal, Ruiting Zong, David L. Nelson, Ghada A. Otaify, Samia Temtamy, Mona Aglan, Mahmoud Issa, Carsten G. Bönnemann, Pablo Lapunzina, Grace Yoon, Victor L. Ruiz-Perez

Nat Commun. 2019; 10: 797. Published online 2019 Feb 15. doi: 10.1038/s41467-019-08548-9

PMCID:: PMC6377633

Abstract Article PDF–11M

Select item 61921215.

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao

Mol Neurodegener. 2018; 13: 56. Published online 2018 Oct 17. doi: 10.1186/s13024-018-0287-z

PMCID:: PMC6192121

Abstract Article PDF–12M

Select item 59570856.

Hypoxia Inducible Factors Modulate Mitochondrial Oxygen Consumption and Transcriptional Regulation of Nuclear-Encoded Electron Transport Chain Genes

Hye Jin Hwang, Scott G. Lynn, Ajith Vengellur, Yogesh Saini, Elizabeth A. Grier, Shelagh M. Ferguson-Miller, John J. LaPres

Biochemistry. Author manuscript; available in PMC 2018 May 17.

Published in final edited form as: Biochemistry. 2015 Jun 23; 54(24): 3739–3748. Published online 2015 Jun 12. doi: 10.1021/bi5012892

PMCID:: PMC5957085

Abstract Article PDF–814K

Select item 55445817.

Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing

Natascha Sommer, Maik Hüttemann, Oleg Pak, Susan Scheibe, Fenja Knoepp, Christopher Sinkler, Monika Malczyk, Mareike Gierhardt, Azadeh Esfandiary, Simone Kraut, Felix Jonas, Christine Veith, Siddhesh Aras, Akylbek Sydykov, Nasim Alebrahimdehkordi, Klaudia Giehl, Matthias Hecker, Ralf P. Brandes, Werner Seeger, Friedrich Grimminger, Hossein A. Ghofrani, Ralph T. Schermuly, Lawrence I. Grossman, Norbert Weissmann

Circ Res. Author manuscript; available in PMC 2018 Aug 4.

Published in final edited form as: Circ Res. 2017 Aug 4; 121(4): 424–438. Published online 2017 Jun 15. doi: 10.1161/CIRCRESAHA.116.310482

PMCID:: PMC5544581

Abstract Article PDF–1.1M

Select item 49515818.

Diverse Functions of Retinoic Acid in Brain Vascular Development

Stephanie Bonney, Susan Harrison-Uy, Swati Mishra, Amber M. MacPherson, Youngshik Choe, Dan Li, Shou-Ching Jaminet, Marcus Fruttiger, Samuel J. Pleasure, Julie A. Siegenthaler

J Neurosci. 2016 Jul 20; 36(29): 7786–7801. doi: 10.1523/JNEUROSCI.3952-15.2016

PMCID:: PMC4951581

Abstract Article PDF–8.3M

Select item 45325009.

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines

Marion Horsch, Juan Antonio Aguilar-Pimentel, Clemens Bönisch, Christophe Côme, Cathrine Kolster-Fog, Klaus T. Jensen, Anders H. Lund, Icksoo Lee, Lawrence I. Grossman, Christopher Sinkler, Maik Hüttemann, Erwin Bohn, Helmut Fuchs, Markus Ollert, Valérie Gailus-Durner, Martin Hrabĕ de Angelis, Johannes Beckers

PLoS One. 2015; 10(8): e0134503. Published online 2015 Aug 11. doi: 10.1371/journal.pone.0134503

PMCID:: PMC4532500

Abstract Article PDF–1.4M

Select item 407087910.

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

Yehudit Zaltsman, Liat Shachnai, Natalie Yivgi-Ohana, Michal Schwarz, Maria Maryanovich, Riekelt H. Houtkooper, Frédéric Maxime Vaz, Francesco De Leonardis, Giuseppe Fiermonte, Ferdinando Palmieri, Bernhard Gillissen, Peter T. Daniel, Erin Jimenez, Susan Walsh, Carla M. Koehler, Soumya Sinha Roy, Ludivine Walter, György Hajnóczky, Atan Gross

Nat Cell Biol. Author manuscript; available in PMC 2014 Jun 25.

Published in final edited form as: Nat Cell Biol. 2010 Jun; 12(6): 553–562. Published online 2010 May 2. doi: 10.1038/ncb2057

PMCID:: PMC4070879

Abstract Article PDF–2.9M

Select item 342582411.

Cytochrome c oxidase subunit 4 isoform 2-knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology

Maik Hüttemann, Icksoo Lee, Xiufeng Gao, Petr Pecina, Alena Pecinova, Jenney Liu, Siddhesh Aras, Natascha Sommer, Thomas H. Sanderson, Monica Tost, Frauke Neff, Juan Antonio Aguilar-Pimentel, Lore Becker, Beatrix Naton, Birgit Rathkolb, Jan Rozman, Jack Favor, Wolfgang Hans, Cornelia Prehn, Oliver Puk, Anja Schrewe, Minxuan Sun, Heinz Höfler, Jerzy Adamski, Raffi Bekeredjian, Jochen Graw, Thure Adler, Dirk H. Busch, Martin Klingenspor, Thomas Klopstock, Markus Ollert, Eckhard Wolf, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Norbert Weissmann, Jeffrey W. Doan, David J. P. Bassett, Lawrence I. Grossman

FASEB J. 2012 Sep; 26(9): 3916–3930. doi: 10.1096/fj.11-203273

PMCID:: PMC3425824

Abstract Article

Select item 328400012.

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism

Nadine Bakkar, Katherine Ladner, Benjamin D. Canan, Sandya Liyanarachchi, Naresh C. Bal, Meghna Pant, Muthu Periasamy, Qiutang Li, Paul M.L. Janssen, Denis C. Guttridge

J Cell Biol. 2012 Feb 20; 196(4): 497–511. doi: 10.1083/jcb.201108118

PMCID:: PMC3284000

Abstract Article PDF–3.3M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310405014.

Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria

Michael A. Kiebish, Xianlin Han, Hua Cheng, Adam Lunceford, Catherine F. Clarke, Hwi Moon, Jeffrey H. Chuang, Thomas N. Seyfried

J Neurochem. Author manuscript; available in PMC 2011 May 30.

Published in final edited form as: J Neurochem. 2008 Jul; 106(1): 299–312. Published online 2008 Jul 1. doi: 10.1111/j.1471-4159.2008.05383.x

PMCID:: PMC3104050

Abstract Article PDF–1.0M

Select item 277884415.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 217328616.

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

Girish V. Putcha, Charles A. Harris, Krista L. Moulder, Rachael M. Easton, Craig B. Thompson, Eugene M. Johnson, Jr.

J Cell Biol. 2002 Apr 29; 157(3): 441–453. doi: 10.1083/jcb.200110108

PMCID:: PMC2173286

Abstract Article PDF–390K

Select item 216941817.

Mammalian Sir2 Homolog SIRT3 Regulates Global Mitochondrial Lysine Acetylation

David B. Lombard, Frederick W. Alt, Hwei-Ling Cheng, Jakob Bunkenborg, Ryan S. Streeper, Raul Mostoslavsky, Jennifer Kim, George Yancopoulos, David Valenzuela, Andrew Murphy, Yinhua Yang, Yaohui Chen, Matthew D. Hirschey, Roderick T. Bronson, Marcia Haigis, Leonard P. Guarente, Robert V. Farese, Jr., Sherman Weissman, Eric Verdin, Bjoern Schwer

Mol Cell Biol. 2007 Dec; 27(24): 8807–8814. Published online 2007 Oct 8. doi: 10.1128/MCB.01636-07