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Select item 115133981.

The influence of perilipin 5 deficiency on gut microbiome profiles in murine metabolic dysfunction-associated fatty liver disease (MAFLD) and MAFLD-hepatocellular carcinoma

Marinela Krizanac, Paula Štancl, Paola Berenice Mass-Sanchez, Rosa Karlić, Diana Moeckel, Twan Lammers, Anastasia Asimakopoulos, Ralf Weiskirchen

Front Cell Infect Microbiol. 2024; 14: 1443654. Published online 2024 Oct 14. doi: 10.3389/fcimb.2024.1443654

PMCID:: PMC11513398

Abstract Article PDF–16M

Select item 110791592.

Perilipin 5 regulates hepatic stellate cell activation and high‐fat diet‐induced non‐alcoholic fatty liver disease

Xuecui Yin, Lin Dong, Xiaohan Wang, Zhenzhen Qin, Yuying Ma, Xiaofei Ke, Ya Li, Qingde Wang, Yang Mi, Quanjun Lyu, Xia Xu, Pengyuan Zheng, Youcai Tang

Animal Model Exp Med. 2024 Apr; 7(2): 166–178. Published online 2023 May 18. doi: 10.1002/ame2.12327

PMCID:: PMC11079159

Abstract Article PDF–17M

Select item 105250323.

PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

Gregory E. Miner, Christina M. So, Whitney Edwards, Joey V. Ragusa, Jonathan T. Wine, Daniel Wong Gutierrez, Michael V. Airola, Laura E. Herring, Rosalind A. Coleman, Eric L. Klett, Sarah Cohen

Dev Cell. Author manuscript; available in PMC 2024 Jul 24.

Published in final edited form as: Dev Cell. 2023 Jul 24; 58(14): 1250–1265.e6. Published online 2023 Jun 7. doi: 10.1016/j.devcel.2023.05.006

PMCID:: PMC10525032

Abstract Article PDF–2.8M

Select item 104784994.

Perilipin 5 deficiency aggravates cardiac hypertrophy by stimulating lactate production in leptin-deficient mice

Lele Jian, Xing Gao, Chao Wang, Xiao Sun, Yuqiao Xu, Ruili Han, Yuying Wang, Shenhui Xu, Lan Ding, Jingjun Zhou, Yu Gu, Yuanlin Zhao, Ying Yang, Yuan Yuan, Jing Ye, Lijun Zhang

Biol Direct. 2023; 18: 54. Published online 2023 Sep 4. doi: 10.1186/s13062-023-00411-8

PMCID:: PMC10478499

Abstract Article PDF–7.3M

Select item 98877535.

Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility

Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Christina Drevinge, Marion Laudette, Entela Bollano, Marcus Henricsson, Johan Tolö, Marcos Bauza Thorbrügge, Max Levin, Malin Lindbom, Muhammad Arif, Pal Pacher, Linda Andersson, Charlotta S Olofsson, Jan Borén, Malin C Levin

Life Sci Alliance. 2023 Apr; 6(4): e202201690. Published online 2023 Jan 30. doi: 10.26508/lsa.202201690

PMCID:: PMC9887753

Abstract Article PDF–2.9M

Select item 91619976.

Plin5 inhibits proliferation and migration of vascular smooth muscle cell through interacting with PGC-1α following vascular injury

Xueqing Gan, Jiaqi Zhao, Yingmei Chen, Yong Li, Bing Xuan, Min Gu, Feifei Feng, Yongjian Yang, Dachun Yang, Xiongshan Sun

Bioengineered. 2022; 13(4): 10665–10678. Published online 2022 Apr 26. doi: 10.1080/21655979.2022.2065762

PMCID:: PMC9161997

Abstract Article PDF–5.3M

Select item 85052337.

Perilipin 5 is a novel target of nuclear receptor LRH-1 to regulate hepatic triglycerides metabolism

Rubee Pantha, Jae-Ho Lee, Jae-Hoon Bae, Eun Hee Koh, Minsang Shin, Dae-Kyu Song, Seung-Soon Im

BMB Rep. 2021 Sep 30; 54(9): 476–481. Published online 2021 Sep 30. doi: 10.5483/BMBRep.2021.54.9.051

PMCID:: PMC8505233

Abstract Article PDF–1.5M

Select item 84671158.

Perilipin 5 Ameliorates Hepatic Stellate Cell Activation via SMAD2/3 and SNAIL Signaling Pathways and Suppresses STAT3 Activation

Rafael Cierpka, Ralf Weiskirchen, Anastasia Asimakopoulos

Cells. 2021 Sep; 10(9): 2184. Published online 2021 Aug 24. doi: 10.3390/cells10092184

PMCID:: PMC8467115

Abstract Article PDF–2.6M

Select item 81755979.

Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

Violeta I. Gallardo-Montejano, Chaofeng Yang, Lisa Hahner, John L. McAfee, Joshua A. Johnson, William L. Holland, Rodrigo Fernandez-Valdivia, Perry E. Bickel

Nat Commun. 2021; 12: 3320. Published online 2021 Jun 3. doi: 10.1038/s41467-021-23601-2

PMCID:: PMC8175597

Abstract Article PDF–4.5M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790076011.

Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control

Stacey N. Keenan, William De Nardo, Jieqiong Lou, Ralf B. Schittenhelm, Magdalene K. Montgomery, James G. Granneman, Elizabeth Hinde, Matthew J. Watt

J Lipid Res. 2021; 62: 100016. Published online 2021 Jan 5. doi: 10.1194/jlr.RA120001126

PMCID:: PMC7900760

Abstract Article PDF–4.3M

Select item 739722212.

EPA/DHA Concentrate by Urea Complexation Decreases Hyperinsulinemia and Increases Plin5 in the Liver of Mice Fed a High-Fat Diet

Alejandra Espinosa, Andrés Ross, Gretel Dovale-Rosabal, Francisco Pino-de la Fuente, Ernesto Uribe-Oporto, Camila Sacristán, Paulina Ruiz, Rodrigo Valenzuela, Nalda Romero, Santiago P. Aubourg, Alicia Rodríguez

Molecules. 2020 Jul; 25(14): 3289. Published online 2020 Jul 20. doi: 10.3390/molecules25143289

PMCID:: PMC7397222

Abstract Article PDF–1.3M

Select item 734892913.

Deletion of Perilipin 5 Protects against Hepatic Injury in Nonalcoholic Fatty Liver Disease via Missing Inflammasome Activation

Anastasia Asimakopoulou, Kathrin M. Engel, Nikolaus Gassler, Thilo Bracht, Barbara Sitek, Eva M. Buhl, Stavroula Kalampoka, Manuela Pinoé-Schmidt, Josef van Helden, Jürgen Schiller, Ralf Weiskirchen

Cells. 2020 Jun; 9(6): 1346. Published online 2020 May 28. doi: 10.3390/cells9061346

PMCID:: PMC7348929

Abstract Article PDF–3.6M

Select item 733821914.

Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice

Stephanie Kolleritsch, Benedikt Kien, Gabriele Schoiswohl, Clemens Diwoky, Renate Schreiber, Christoph Heier, Lisa Katharina Maresch, Martina Schweiger, Thomas O. Eichmann, Sarah Stryeck, Petra Krenn, Tamara Tomin, Matthias Schittmayer, Dagmar Kolb, Thomas Rülicke, Gerald Hoefler, Heimo Wolinski, Tobias Madl, Ruth Birner-Gruenberger, Guenter Haemmerle

Cardiovasc Res. Author manuscript; available in PMC 2020 Jul 6.

Published in final edited form as: Cardiovasc Res. 2020 Feb 1; 116(2): 339–352. doi: 10.1093/cvr/cvz119

Correction in:: Cardiovasc Res. 2019 Nov 1; 115(13): 1906.

PMCID:: PMC7338219

Abstract Article PDF–1.6M

Select item 705725815.

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez

Cell Rep. 2019 Nov 5; 29(6): 1410–1418.e6. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.073

PMCID:: PMC7057258

Abstract Article

Select item 705383016.

Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting

Enxiang Zhang, Wenqi Cui, Michael Lopresti, Mara T. Mashek, Charles P. Najt, Hongbo Hu, Douglas G. Mashek

J Lipid Res. 2020 Mar; 61(3): 338–350. Published online 2020 Jan 13. doi: 10.1194/jlr.RA119000336

PMCID:: PMC7053830

Abstract Article PDF–2.3M

Select item 645178617.

Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver

Jin Zhang, Xing Gao, Yuan Yuan, Chao Sun, Yuanlin Zhao, Liming Xiao, Ying Yang, Yu Gu, Risheng Yang, Peizhen Hu, Lijun Zhang, Chao Wang, Jing Ye

Lipids Health Dis. 2019; 18: 87. Published online 2019 Apr 6. doi: 10.1186/s12944-019-1022-7

PMCID:: PMC6451786

Abstract Article PDF–4.8M

Select item 583292718.

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells

Jianguo Lin, Shizhong Zheng, Alan D. Attie, Mark P. Keller, David A. Bernlohr, William S. Blaner, Elizabeth P. Newberry, Nicholas O. Davidson, Anping Chen

J Lipid Res. 2018 Mar; 59(3): 416–428. Published online 2018 Jan 9. doi: 10.1194/jlr.M077487

PMCID:: PMC5832927

Abstract Article PDF–1.6M

Select item 531693219.

Plin5 alleviates myocardial ischaemia/reperfusion injury by reducing oxidative stress through inhibiting the lipolysis of lipid droplets

Pengfei Zheng, Zhonglin Xie, Yuan Yuan, Wen Sui, Chao Wang, Xing Gao, Yuanlin Zhao, Feng Zhang, Yu Gu, Peizhen Hu, Jing Ye, Xuyang Feng, Lijun Zhang

Sci Rep. 2017; 7: 42574. Published online 2017 Feb 20. doi: 10.1038/srep42574

PMCID:: PMC5316932

Abstract Article PDF–1.8M

Select item 513883820.

Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle

Claire Laurens, Virginie Bourlier, Aline Mairal, Katie Louche, Pierre-Marie Badin, Etienne Mouisel, Alexandra Montagner, André Marette, Angelo Tremblay, John S. Weisnagel, Hervé Guillou, Dominique Langin, Denis R. Joanisse, Cedric Moro

Sci Rep. 2016; 6: 38310. Published online 2016 Dec 6. doi: 10.1038/srep38310

PMCID:: PMC5138838

Abstract Article PDF–1.6M

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