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Items: 1 to 20 of 94

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity, and prevent transformation
Robin D. Lee, Todd P. Knutson, Sarah A. Munro, Jeffrey T. Miller, Lynn M. Heltemes-Harris, Charles G. Mullighan, Kristen Jepsen, Michael A. Farrar
Nat Immunol. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: Nat Immunol. 2022 Dec; 23(12): 1763–1776. Published online 2022 Oct 31. doi: 10.1038/s41590-022-01343-7
PMCID:
PMC9772092
AbstractArticlePDF–6.3M
3.
Nuclear corepressor SMRT acts as a strong regulator of both β-oxidation and suppressor of fibrosis in the differentiation process of mouse skeletal muscle cells
Hiroaki Shimizu, Yasuhiro Horibata, Izuki Amano, Megan J. Ritter, Mariko Domae, Hiromi Ando, Hiroyuki Sugimoto, Ronald N. Cohen, Anthony N. Hollenberg
PLoS One. 2022; 17(12): e0277830. Published online 2022 Dec 1. doi: 10.1371/journal.pone.0277830
PMCID:
PMC9714868
AbstractArticlePDF–7.9M
4.
SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling
Atimukta Jha, Abdul Ahad, Gyan Prakash Mishra, Kaushik Sen, Shuchi Smita, Aliva Prity Minz, Viplov Kumar Biswas, Archana Tripathy, Shantibhushan Senapati, Bhawna Gupta, Hans Acha-Orbea, Sunil Kumar Raghav
Front Immunol. 2022; 13: 910705. Published online 2022 Sep 27. doi: 10.3389/fimmu.2022.910705
PMCID:
PMC9552960
AbstractArticlePDF–11M
5.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
6.
Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis
Megan J. Ritter, Izuki Amano, Norihiro Imai, Lorraine Soares De Oliveira, Kristen R. Vella, Anthony N. Hollenberg
Mol Metab. 2021 Nov; 53: 101315. Published online 2021 Aug 12. doi: 10.1016/j.molmet.2021.101315
PMCID:
PMC8429965
AbstractArticlePDF–3.5M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
The uncharacterized SANT and BTB domain-containing protein SANBR inhibits class switch recombination
Simin Zheng, Allysia J. Matthews, Numa Rahman, Kayleigh Herrick-Reynolds, Emily Sible, Jee Eun Choi, Alec Wishnie, Yan Kee Ng, Daniela Rhodes, Stephen J. Elledge, Bao Q. Vuong
J Biol Chem. 2021 Jan-Jun; 296: 100625. Published online 2021 Apr 6. doi: 10.1016/j.jbc.2021.100625
PMCID:
PMC8141524
AbstractArticlePDF–1.1M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Ncor2/PPARα-Dependent Upregulation of MCUb in the Type 2 Diabetic Heart Impacts Cardiac Metabolic Flexibility and Function
Federico Cividini, Brian T. Scott, Jorge Suarez, Darren E. Casteel, Sven Heinz, Anzhi Dai, Tanja Diemer, Jorge A. Suarez, Christopher W. Benner, Majid Ghassemian, Wolfgang H. Dillmann
Diabetes. 2021 Mar; 70(3): 665–679. Published online 2020 Dec 10. doi: 10.2337/db20-0779
PMCID:
PMC7897348
AbstractArticlePDF–3.8M
11.
Dichotomous Engagement of HDAC3 Activity Governs Inflammatory Responses
Hoang C. B. Nguyen, Marine Adlanmerini, Amy K. Hauck, Mitchell A. Lazar
Nature. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: Nature. 2020 Aug; 584(7820): 286–290. Published online 2020 Aug 5. doi: 10.1038/s41586-020-2576-2
PMCID:
PMC7725280
AbstractArticlePDF–4.5M
12.
SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem
Jonathan H Kahn, Anna Goddi, Aishwarya Sharma, Joshua Heiman, Alanis Carmona, Yan Li, Alexandria Hoffman, Kelly Schoenfelt, Honggang Ye, Alexandria M Bobe, Lev Becker, Anthony N Hollenberg, Ronald N Cohen
Endocrinology. 2020 Oct; 161(10): bqaa132. Published online 2020 Aug 8. doi: 10.1210/endocr/bqaa132
PMCID:
PMC7478322
AbstractArticle
13.
A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain
Attilio Iemolo, Patricia Montilla-Perez, I-Chi Lai, Yinuo Meng, Syreeta Nolan, Junneng Wen, Iulia Rusu, Davide Dulcis, Francesca Telese
J Comp Neurol. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: J Comp Neurol. 2020 Sep 1; 528(13): 2218–2238. Published online 2020 Feb 24. doi: 10.1002/cne.24886
PMCID:
PMC7368833
AbstractArticlePDF–7.4M
14.
HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity
Katherine M. Szigety, Fang Liu, Chase Y. Yuan, Deborah J. Moran, Jeremy Horrell, Heather R. Gochnauer, Ronald N. Cohen, Jonathan P. Katz, Klaus H. Kaestner, John T. Seykora, John W. Tobias, Mitchell A. Lazar, Mingang Xu, Sarah E. Millar
Genes Dev. 2020 Jul 1; 34(13-14): 973–988. doi: 10.1101/gad.333674.119
PMCID:
PMC7328513
AbstractArticlePDF–22M
15.
Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action
Hiroaki Shimizu, Yu Lu, Kristen R. Vella, Federico Damilano, Inna Astapova, Izuki Amano, Megan Ritter, Molly R. Gallop, Anthony N. Rosenzweig, Ronald N. Cohen, Anthony N. Hollenberg
PLoS One. 2019; 14(8): e0220717. Published online 2019 Aug 12. doi: 10.1371/journal.pone.0220717
PMCID:
PMC6690520
AbstractArticlePDF–2.0M
16.
ARNT2 tunes activity-dependent gene expression through NCoR2-mediated repression and NPAS4-mediated activation
Nikhil Sharma, Elizabeth A. Pollina, M. Aurel Nagy, Ee-Lynn Yap, Florence A. DiBiase, Sinisa Hrvatin, Linda Hu, Cindy Lin, Michael E. Greenberg
Neuron. Author manuscript; available in PMC 2020 Apr 17.
Published in final edited form as: Neuron. 2019 Apr 17; 102(2): 390–406.e9. Published online 2019 Mar 4. doi: 10.1016/j.neuron.2019.02.007
PMCID:
PMC6504996
AbstractArticlePDF–2.8M
17.
NCOR1/2 loss of function impairs memory through a novel GABAergic hypothalamus–CA3 projection
Wenjun Zhou, Yanlin He, Atteeq U. Rehman, Yan Kong, Sungguan Hong, Guolian Ding, Hari Krishna Yalamanchili, Ying-Wooi Wan, Basil Paul, Chuhan Wang, Yingyun Gong, Wenxian Zhou, Hao Liu, John Dean, Emmanuel Scalais, Mary O’Driscoll, Jenny E.V. Morton, DDD study, Xinguo Hou, Qi Wu, Qingchun Tong, Zhandong Liu, Pengfei Liu, Yong Xu, Zheng Sun
Nat Neurosci. Author manuscript; available in PMC 2019 Jul 21.
Published in final edited form as: Nat Neurosci. 2019 Feb; 22(2): 205–217. Published online 2019 Jan 21. doi: 10.1038/s41593-018-0311-1
Correction in:
Nat Neurosci. 2019 Jun 20
PMCID:
PMC6361549
AbstractArticlePDF–1.5M
18.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
19.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
20.
Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis
Suk-Hyun Hong, Sungsoon Fang, Benson C. Lu, Russell Nofsinger, Yasuhiko Kawakami, Glenda L. Castro, Yunqiang Yin, Chengqi Lin, Ruth T. Yu, Michael Downes, Juan Carlos Izpisúa Belmonte, Ali Shilatifard, Ronald M. Evans
Proc Natl Acad Sci U S A. 2018 Oct 9; 115(41): 10381–10386. Published online 2018 Sep 25. doi: 10.1073/pnas.1809480115
PMCID:
PMC6187131
AbstractArticlePDF–1.3M

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