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Items: 1 to 20 of 65

1.
Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease
Fei Han, Shi Wu, Ya Dong, Yanjie Liu, Bei Sun, Liming Chen
J Transl Med. 2024; 22: 465. Published online 2024 May 16. doi: 10.1186/s12967-024-05207-6
PMCID:
PMC11100153
AbstractArticlePDF–10M
2.
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo
Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis, Jr
Nat Commun. 2024; 15: 2142. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46463-w
PMCID:
PMC10923867
AbstractArticlePDF–7.3M
3.
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice
Min Chen, Jie-Ying Zhu, Wang-Jing Mu, Hong-Yang Luo, Yang Li, Shan Li, Lin-Jing Yan, Ruo-Ying Li, Liang Guo
Nat Commun. 2023; 14: 8391. Published online 2023 Dec 18. doi: 10.1038/s41467-023-44242-7
PMCID:
PMC10728194
AbstractArticlePDF–8.0M
4.
CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle
Florentina Negoita, Alex B. Addinsall, Kristina Hellberg, Conchita Fraguas Bringas, Paul S. Hafen, Tyler J. Sermersheim, Marianne Agerholm, Christopher T.A. Lewis, Danial Ahwazi, Naomi X.Y. Ling, Jeppe K. Larsen, Atul S. Deshmukh, Mohammad A. Hossain, Jonathan S. Oakhill, Julien Ochala, Jeffrey J. Brault, Uma Sankar, David H. Drewry, John W. Scott, Carol A. Witczak, Kei Sakamoto
Mol Metab. 2023 Sep; 75: 101761. Published online 2023 Jun 26. doi: 10.1016/j.molmet.2023.101761
PMCID:
PMC10362367
AbstractArticlePDF–3.0M
5.
Calcium/Calmodulin-Dependent Protein Kinase Kinase β (CaMKK β) is Neuroprotective in Stroke in Aged Mice
Lin Liu, Hui Yuan, Kyle Denton, Xue-jun Li, Louise McCullough, Jun Li
Eur J Neurosci. Author manuscript; available in PMC 2023 May 23.
Published in final edited form as: Eur J Neurosci. 2016 Aug; 44(4): 2139–2146. doi: 10.1111/ejn.13299
PMCID:
PMC10204777
AbstractArticlePDF–1.2M
6.
CaMKK2 Knockout Bone Marrow Cells Collected/Processed in Low Oxygen (Physioxia) Suggests CaMKK2 as a Hematopoietic Stem to Progenitor Differentiation Fate Determinant
Hal E. Broxmeyer, James Ropa, Maegan L. Capitano, Scott Cooper, Luigi Racioppi, Uma Sankar
Stem Cell Rev Rep. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Stem Cell Rev Rep. 2022 Oct; 18(7): 2513–2521. Published online 2022 Mar 9. doi: 10.1007/s12015-021-10306-8
PMCID:
PMC10072181
AbstractArticlePDF–800K
7.
Osteocyte-Derived CaMKK2 Regulates Osteoclasts and Bone Mass in a Sex-Dependent Manner through Secreted Calpastatin
Justin N. Williams, Mavis Irwin, Yong Li, Anuradha Valiya Kambrath, Brett T. Mattingly, Sheel Patel, Mizuho Kittaka, Rebecca N. Collins, Nicholas A. Clough, Emma H. Doud, Amber L. Mosley, Teresita Bellido, Angela Bruzzaniti, Lilian I. Plotkin, Jonathan C. Trinidad, William R. Thompson, Lynda F. Bonewald, Uma Sankar
Int J Mol Sci. 2023 Mar; 24(5): 4718. Published online 2023 Mar 1. doi: 10.3390/ijms24054718
PMCID:
PMC10003151
AbstractArticlePDF–9.4M
8.
Increased CaMKK2 expression is an adaptive response that maintains the fitness of tumor-infiltrating natural killer cells
Patrick K. Juras, Luigi Racioppi, Debarati Mukherjee, Sandeep Artham, Xia Gao, Laura Akullian D’Agostino, Ching-Yi Chang, Donald P. McDonnell
Cancer Immunol Res. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Cancer Immunol Res. 2023 Jan 3; 11(1): 109–122. doi: 10.1158/2326-6066.CIR-22-0391
PMCID:
PMC9812906
AbstractArticlePDF–1.0M
9.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin
Nat Metab. 2022; 4(10): 1369–1401. Published online 2022 Oct 10. doi: 10.1038/s42255-022-00640-7
PMCID:
PMC9584815
AbstractArticlePDF–9.0M
10.
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
Annie Lee, Chandana Kondapalli, Daniel M. Virga, Tommy L. Lewis, Jr, So Yeon Koo, Archana Ashok, Georges Mairet-Coello, Sebastien Herzig, Marc Foretz, Benoit Viollet, Reuben Shaw, Andrew Sproul, Franck Polleux
Nat Commun. 2022; 13: 4444. Published online 2022 Aug 1. doi: 10.1038/s41467-022-32130-5
PMCID:
PMC9343354
AbstractArticlePDF–8.1M
11.
LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response
Sandy MacMillan, Andrew P. Holmes, Mark L. Dallas, Amira D. Mahmoud, Michael J. Shipston, Chris Peers, D. Grahame Hardie, Prem Kumar, A. Mark Evans
Commun Biol. 2022; 5: 642. Published online 2022 Jun 29. doi: 10.1038/s42003-022-03583-7
Correction in:
Commun Biol. 2022; 5: 765.
PMCID:
PMC9243028
AbstractArticlePDF–2.4M
12.
Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer
Thomas L. Pulliam, Dominik Awad, Jenny J. Han, Mollianne M. Murray, Jeffrey J. Ackroyd, Pavithr Goli, Jonathan S. Oakhill, John W. Scott, Michael M. Ittmann, Daniel E. Frigo
Cells. 2022 Jun; 11(12): 1890. Published online 2022 Jun 10. doi: 10.3390/cells11121890
PMCID:
PMC9221545
AbstractArticlePDF–4.7M
13.
A molecular complex of Cav1.2/CaMKK2/CaMK1a in caveolae is responsible for vascular remodeling via excitation–transcription coupling
Yoshiaki Suzuki, Takumi Ozawa, Tomo Kurata, Nanami Nakajima, Gerald W. Zamponi, Wayne R. Giles, Yuji Imaizumi, Hisao Yamamura
Proc Natl Acad Sci U S A. 2022 Apr 19; 119(16): e2117435119. Published online 2022 Apr 11. doi: 10.1073/pnas.2117435119
PMCID:
PMC9169798
AbstractArticlePDF–2.8M
14.
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism
Brittany A. Stork, Adam Dean, Andrea R. Ortiz, Pradip Saha, Nagireddy Putluri, Maricarmen D. Planas-Silva, Iqbal Mahmud, Kimal Rajapakshe, Cristian Coarfa, Stefan Knapp, Philip L. Lorenzi, Bruce E. Kemp, Benjamin E. Turk, John W. Scott, Anthony R. Means, Brian York
Mol Metab. 2022 Aug; 62: 101513. Published online 2022 May 11. doi: 10.1016/j.molmet.2022.101513
PMCID:
PMC9157561
AbstractArticlePDF–3.0M
15.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
16.
microRNA-378b regulates ethanol-induced hepatic steatosis by targeting CaMKK2 to mediate lipid metabolism
Ying-Zhao Wang, Jun Lu, Yuan-Yuan Li, Yu-Juan Zhong, Cheng-Fang Yang, Yan Zhang, Li-Hua Huang, Su-Mei Huang, Qi-Ran Li, Dan Wu, Meng-Wei Song, Lin Shi, Li Li, Yong-Wen Li
Bioengineered. 2021; 12(2): 12659–12676. Published online 2021 Dec 20. doi: 10.1080/21655979.2021.2003677
PMCID:
PMC8810039
AbstractArticlePDF–4.8M
17.
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling
Jun Seok Son, Song Ah Chae, Liang Zhao, Hongyang Wang, Jeanene M. de Avila, Mei-Jun Zhu, Zhihua Jiang, Min Du
EBioMedicine. 2022 Feb; 76: 103842. Published online 2022 Jan 23. doi: 10.1016/j.ebiom.2022.103842
PMCID:
PMC8790600
AbstractArticlePDF–4.3M
18.
Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells
Wei Huang, Yaping Liu, Anthony Luz, Mark Berrong, Joel N. Meyer, Yujing Zou, Excel Swann, Pasupathi Sundaramoorthy, Yubin Kang, Shekeab Jauhari, William Lento, Nelson Chao, Luigi Racioppi
Front Immunol. 2021; 12: 754083. Published online 2021 Oct 12. doi: 10.3389/fimmu.2021.754083
PMCID:
PMC8546266
AbstractArticlePDF–6.0M
19.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
20.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M

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