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Select item 112316651.

Argonaute 2 restored erectile function and corpus cavernosum mitochondrial function by reducing apoptosis in a mouse model of cavernous nerve injury

Yan Huang, Guo Nan Yin, Fang-Yuan Liu, Fitri Rahma Fridayana, Lashkari Niloofar, Minh Nhat Vo, Ji-Kan Ryu

Investig Clin Urol. 2024 Jul; 65(4): 400–410. Published online 2024 Jun 24. doi: 10.4111/icu.20240077

PMCID:: PMC11231665

Abstract Article PDF–24M

Select item 110572252.

Ablation of Argonaute 2 in Schwann cells accelerates the progression of diabetic peripheral neuropathy

Baoyan Fan, Michael Chopp, Yi Zhang, Xinli Wang, Amy Kemper, Zheng Gang Zhang, Xian Shuang Liu

Glia. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Glia. 2023 Sep; 71(9): 2196–2209. Published online 2023 May 13. doi: 10.1002/glia.24387

PMCID:: PMC11057225

Abstract Article PDF–2.2M

Select item 109365993.

Pycard deficiency inhibits microRNA maturation and prevents neointima formation by promoting chaperone-mediated autophagic degradation of AGO2/argonaute 2 in adipose tissue

Jian Li, Hongmin Yao, Fujie Zhao, Junqing An, Qilong Wang, Jing Mu, Zhixue Liu, Ming-Hui Zou, Zhonglin Xie

Autophagy. 2024; 20(3): 629–644. Published online 2023 Nov 14. doi: 10.1080/15548627.2023.2277610

PMCID:: PMC10936599

Abstract Article PDF–5.3M

Select item 105601144.

hsa_circ_0129047 Upregulates LYVE1 to Inhibit Hepatocellular Carcinoma Progression by Sponging miR-492

Zhenzhen Feng, Jiyuan Wu

Dis Markers. 2023; 2023: 6978234. Published online 2023 Sep 30. doi: 10.1155/2023/6978234

PMCID:: PMC10560114

Abstract Article PDF–1.6M

Select item 105278625.

Oncogenic K-Ras suppresses global miRNA function

Bing Shui, Tyler S. Beyett, Zhengyi Chen, Xiaoyi Li, Gaspare La Rocca, William M. Gazlay, Michael J. Eck, Ken S. Lau, Andrea Ventura, Kevin M. Haigis

Mol Cell. Author manuscript; available in PMC 2024 Jul 20.

Published in final edited form as: Mol Cell. 2023 Jul 20; 83(14): 2509–2523.e13. Published online 2023 Jul 3. doi: 10.1016/j.molcel.2023.06.008

PMCID:: PMC10527862

Abstract Article PDF–1.6M

Select item 103078526.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102443777.

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways

Aditya Kshirsagar, Svetlana Maslov Doroshev, Anna Gorelik, Tsviya Olender, Tamar Sapir, Daisuke Tsuboi, Irit Rosenhek-Goldian, Sergey Malitsky, Maxim Itkin, Amir Argoetti, Yael Mandel-Gutfreund, Sidney R. Cohen, Jacob H. Hanna, Igor Ulitsky, Kozo Kaibuchi, Orly Reiner

Nat Commun. 2023; 14: 3293. Published online 2023 Jun 6. doi: 10.1038/s41467-023-38797-8

PMCID:: PMC10244377

Abstract Article PDF–8.5M

Select item 101610018.

Ago2 and a miRNA reduce Topoisomerase 1 for enhancing DNA cleavage in antibody diversification by activation-induced cytidine deaminase

Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koichiro Higasa, Fumihiko Matsuda, Tasuku Honjo

Proc Natl Acad Sci U S A. 2023 May 2; 120(18): e2216918120. Published online 2023 Apr 24. doi: 10.1073/pnas.2216918120

PMCID:: PMC10161001

Abstract Article PDF–4.1M

Select item 99180489.

Argonaute 2 Restores Erectile Function by Enhancing Angiogenesis and Reducing Reactive Oxygen Species Production in Streptozotocin (STZ)-Induced Type-1 Diabetic Mice

Fang-Yuan Liu, Guo Nan Yin, Jiyeon Ock, Fitri Rahma Fridayana, Lashkari Niloofar, Yan Huang, Minh Nhat Vo, Jun-Kyu Suh, Soon-Sun Hong, Ju-Hee Kang, Ji-Kan Ryu

Int J Mol Sci. 2023 Feb; 24(3): 2935. Published online 2023 Feb 2. doi: 10.3390/ijms24032935

PMCID:: PMC9918048

Abstract Article PDF–7.7M

Select item 960386010.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 952898611.

Widespread association of the Argonaute protein AGO2 with meiotic chromatin suggests a distinct nuclear function in mammalian male reproduction

Kimberly N. Griffin, Benjamin William Walters, Haixin Li, Huafeng Wang, Giulia Biancon, Toma Tebaldi, Carolyn B. Kaya, Jean Kanyo, TuKiet T. Lam, Andy L. Cox, Stephanie Halene, Jean-Ju Chung, Bluma J. Lesch

Genome Res. 2022 Sep; 32(9): 1655–1668. doi: 10.1101/gr.276578.122

PMCID:: PMC9528986

Abstract Article PDF–4.5M

Select item 943761012.

STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals

Shumin Zhang, Xuhua Zhang, Yuanyuan Bie, Jing Kong, An Wang, Yang Qiu, Xi Zhou

Virol Sin. 2022 Aug; 37(4): 569–580. Published online 2022 May 6. doi: 10.1016/j.virs.2022.05.001

PMCID:: PMC9437610

Abstract Article PDF–3.0M

Select item 893110713.

Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1^G93A mice

Dillon Shapiro, Ryan Massopust, Thomas Taetzsch, Gregorio Valdez

Sci Rep. 2022; 12: 4630. Published online 2022 Mar 17. doi: 10.1038/s41598-022-08455-y

PMCID:: PMC8931107

Abstract Article PDF–8.0M

Select item 867159014.

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development

Yin Zhang, Ye-Ya Tan, Pei-Pei Chen, Hui Xu, Shu-Juan Xie, Shi-Jun Xu, Bin Li, Jun-Hao Li, Shun Liu, Jian-Hua Yang, Hui Zhou, Liang-Hu Qu

Cell Death Dis. 2021 Dec; 12(12): 1161. Published online 2021 Dec 14. doi: 10.1038/s41419-021-04436-7

PMCID:: PMC8671590

Abstract Article PDF–5.3M

Select item 844704515.

Retinal Degeneration Caused by Ago2 Disruption

Xue-Jiao Chen, Chang-Jun Zhang, Ya-Han Wang, Zi-Bing Jin

Invest Ophthalmol Vis Sci. 2021 Sep; 62(12): 14. Published online 2021 Sep 16. doi: 10.1167/iovs.62.12.14

PMCID:: PMC8447045

Abstract Article PDF–20M

Select item 815791716.

AGO2 promotes tumor progression in KRAS-driven mouse models of non–small cell lung cancer

Jean Ching-Yi Tien, Seema Chugh, Andrew E. Goodrum, Yunhui Cheng, Rahul Mannan, Yuping Zhang, Lisha Wang, Vijaya L. Dommeti, Xiaoming Wang, Alice Xu, Jennifer Hon, Carson Kenum, Fengyun Su, Rui Wang, Xuhong Cao, Sunita Shankar, Arul M. Chinnaiyan

Proc Natl Acad Sci U S A. 2021 May 18; 118(20): e2026104118. Published online 2021 May 10. doi: 10.1073/pnas.2026104118

PMCID:: PMC8157917

Abstract Article PDF–1.8M

Select item 809881417.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790660219.

Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs

Qiuying Liu, Xiaoli Chen, Mariah K Novak, Shaojie Zhang, Wenqian Hu

eLife. 2021; 10: e66288. Published online 2021 Feb 18. doi: 10.7554/eLife.66288

PMCID:: PMC7906602

Abstract Article PDF–3.2M

Select item 787517520.

Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery

Jashdeep Bhattacharjee, Vishnupriya J Borra, Esam S B Salem, Cai Zhang, Kazutoshi Murakami, Rupinder K Gill, Ahlee Kim, James K Kim, Rosa-Maria Salazar-Gonzalez, Mikako Warren, Rohit Kohli, Takahisa Nakamura

Endocrinology. 2021 Apr; 162(4): bqab007. Published online 2021 Jan 11. doi: 10.1210/endocr/bqab007

PMCID:: PMC7875175

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