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Select item 109424671.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 107662022.

ALDH1A3 promotes invasion and metastasis in triple‐negative breast cancer by regulating the plasminogen activation pathway

Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato

Mol Oncol. 2024 Jan; 18(1): 91–112. Published online 2023 Oct 9. doi: 10.1002/1878-0261.13528

PMCID:: PMC10766202

Abstract Article PDF–4.9M

Select item 106491343.

Enhanced Sensitivity to ALDH1A3-Dependent Ferroptosis in TMZ-Resistant Glioblastoma Cells

Yang Wu, Sophie Franzmeier, Friederike Liesche-Starnecker, Jürgen Schlegel

Cells. 2023 Nov; 12(21): 2522. Published online 2023 Oct 25. doi: 10.3390/cells12212522

PMCID:: PMC10649134

Abstract Article PDF–3.3M

Select item 105458244.

Clinical and genetic analysis further delineates the phenotypic spectrum of ALDH1A3-related anophthalmia and microphthalmia

Yesim Kesim, Fabiola Ceroni, Alejandra Damián, Fiona Blanco-Kelly, Carmen Ayuso, Kathy Williamson, Véronique Paquis-Flucklinger, Dorine A Bax, Julie Plaisancié, Claudine Rieubland, Mostafa Chamlal, Marta Cortón, Nicolas Chassaing, Patrick Calvas, Nicola K Ragge

Eur J Hum Genet. 2023 Oct; 31(10): 1175–1180. Published online 2023 Mar 31. doi: 10.1038/s41431-023-01342-8

Correction in:: Eur J Hum Genet. 2023 Oct; 31(10): 1196–1198.

PMCID:: PMC10545824

Abstract Article PDF–1.1M

Select item 100856155.

MiR-320b aberrant expression enhances the radioresistance of human glioma via upregulated expression of ALDH1A3

Ping Mao, Tuo Wang, Ke Gao, Yi Li, Changwang Du, Maode Wang

Aging (Albany NY) 2023 Mar 31; 15(6): 2347–2357. Published online 2023 Mar 29. doi: 10.18632/aging.204617

PMCID:: PMC10085615

Abstract Article PDF–1.2M

Select item 94754536.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 90079728.

Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3

Albert Castellví, Raquel Pequerul, Vito Barracco, Judith Juanhuix, Xavier Parés, Jaume Farrés

Commun Biol. 2022; 5: 354. Published online 2022 Apr 13. doi: 10.1038/s42003-022-03311-1

PMCID:: PMC9007972

Abstract Article PDF–3.2M

Select item 85057969.

Aldehyde dehydrogenase 1A1 and 1A3 isoforms – mechanism of activation and regulation in cancer

M. Poturnajova, Z. Kozovska, M. Matuskova

Cell Signal. 2021 Nov; 87: 110120. doi: 10.1016/j.cellsig.2021.110120

PMCID:: PMC8505796

Abstract Article

Select item 845559410.

Disruption of KDM4C-ALDH1A3 feed-forward loop inhibits stemness, tumorigenesis and chemoresistance of gastric cancer stem cells

Tingyuan Lang, Jia Xu, Lei Zhou, Zhiqi Zhang, Xinli Ma, Jiayi Gu, Jingshu Liu, Yunzhe Li, Dongyan Ding, Jiangfeng Qiu

Signal Transduct Target Ther. 2021; 6: 336. Published online 2021 Sep 22. doi: 10.1038/s41392-021-00674-5

PMCID:: PMC8455594

Article PDF–1.4M

Select item 828956511.

ALDH1A3 Coordinates Metabolism with Gene Regulation in Pulmonary Arterial Hypertension

Dan Li, Ning-Yi Shao, Jan-Renier Moonen, Zhixin Zhao, Minyi Shi, Shoichiro Otsuki, Lingli Wang, Tiffany Nguyen, Elaine Yan, David P. Marciano, Kévin Contrepois, Caiyun G. Li, Joseph C. Wu, Michael P. Snyder, Marlene Rabinovitch

Circulation. Author manuscript; available in PMC 2022 May 25.

Published in final edited form as: Circulation. 2021 May 25; 143(21): 2074–2090. Published online 2021 Mar 25. doi: 10.1161/CIRCULATIONAHA.120.048845

PMCID:: PMC8289565

Abstract Article PDF–2.3M

Select item 821016212.

A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells

Muhammad Sohail, Lulzim Shkreta, Johanne Toutant, Safwat Rabea, Jean-Philippe Babeu, Caroline Huard, Jasmin Coulombe-Huntington, Aurélie Delannoy, Morgane Placet, Sameh Geha, Fernand-Pierre Gendron, François Boudreau, Mike Tyers, David S Grierson, Benoit Chabot

NAR Cancer. 2021 Jun; 3(2): zcab019. Published online 2021 May 25. doi: 10.1093/narcan/zcab019

PMCID:: PMC8210162

Abstract Article PDF–5.8M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 736879214.

The predominant expression of cancer stem cell marker ALDH1A3 in tumor infiltrative area is associated with shorter overall survival of human glioblastoma

Chao Gan, Daniela Pierscianek, Nicolai El Hindy, Yahya Ahmadipour, Kathy Keyvani, Ulrich Sure, Yuan Zhu

BMC Cancer. 2020; 20: 672. Published online 2020 Jul 17. doi: 10.1186/s12885-020-07153-0

PMCID:: PMC7368792

Abstract Article PDF–5.4M

Select item 735777115.

High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients

Yuka Nozaki, Hitomi Motomura, Shoma Tamori, Yumiko Kimura, Chotaro Onaga, Shotaro Kanai, Yuka Ishihara, Ayaka Ozaki, Yasushi Hara, Yohsuke Harada, Yasunari Mano, Tsugumichi Sato, Keiko Sato, Kazunori Sasaki, Hitoshi Ishiguro, Shigeo Ohno, Kazunori Akimoto

PLoS One. 2020; 15(7): e0235747. Published online 2020 Jul 13. doi: 10.1371/journal.pone.0235747

PMCID:: PMC7357771

Abstract Article PDF–2.7M

Select item 720603016.

ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells

Dejan Vidovic, Thomas T. Huynh, Prathyusha Konda, Cheryl Dean, Brianne M. Cruickshank, Mohammad Sultan, Krysta M. Coyle, Shashi Gujar, Paola Marcato

Cell Death Differ. 2020 Jan; 27(1): 363–378. Published online 2019 Jun 13. doi: 10.1038/s41418-019-0362-1

PMCID:: PMC7206030

Abstract Article PDF–5.8M

Select item 720178717.

ALDH1A3 serves as a predictor for castration resistance in prostate cancer patients

Shangqian Wang, Xiang Zhou, Chao Liang, Meiling Bao, Ye Tian, Jundong Zhu, Tongtong Zhang, Jie Yang, Zengjun Wang

BMC Cancer. 2020; 20: 387. Published online 2020 May 6. doi: 10.1186/s12885-020-06899-x

PMCID:: PMC7201787

Abstract Article PDF–1.8M

Select item 718947718.

MIR600HG suppresses metastasis and enhances oxaliplatin chemosensitivity by targeting ALDH1A3 in colorectal cancer

Yi Yao, Nan Li

Biosci Rep. 2020 Apr 30; 40(4): BSR20200390. Published online 2020 Apr 28. doi: 10.1042/BSR20200390

Retraction in:: Biosci Rep. 2024 Sep 25; 44(9): BSR-2020-0390_RET.

PMCID:: PMC7189477

Abstract Article

Select item 711512819.

Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan

Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam

Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525

PMCID:: PMC7115128

Abstract Article PDF–1.6M

Select item 706047420.

ALDH1A3‐mTOR axis as a therapeutic target for anticancer drug‐tolerant persister cells in gastric cancer

Ryuhei Kawakami, Tetsuo Mashima, Naomi Kawata, Koshi Kumagai, Toshiro Migita, Takeshi Sano, Nobuyuki Mizunuma, Kensei Yamaguchi, Hiroyuki Seimiya

Cancer Sci. 2020 Mar; 111(3): 962–973. Published online 2020 Feb 11. doi: 10.1111/cas.14316

PMCID:: PMC7060474

Abstract Article PDF–1.8M

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