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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Adverse maternal environment alters Oprl1 variant expression in mouse hippocampus
Xingrao Ke, Yingliu Huang, Qi Fu, Amber Majnik, Venkatesh Sampath, Robert H. Lane
Anat Rec (Hoboken) 2023 Jan; 306(1): 162–175. Published online 2022 Aug 19. doi: 10.1002/ar.25056
PMCID:
PMC10087895
AbstractArticlePDF–3.5M
3.
Activation of the nociceptin/orphanin-FQ receptor promotes NREM sleep and EEG slow wave activity
Stephen R. Morairty, Yu Sun, Lawrence Toll, Michael R. Bruchas, Thomas S. Kilduff
Proc Natl Acad Sci U S A. 2023 Mar 28; 120(13): e2214171120. Published online 2023 Mar 22. doi: 10.1073/pnas.2214171120
PMCID:
PMC10068791
AbstractArticlePDF–3.3M
4.
Peripheral ablation of type III adenylyl cyclase induces hyperalgesia and eliminates KOR-mediated analgesia in mice
Wen-Wen Zhang, Hong Cao, Yang Li, Xian-Jun Fu, Yu-Qiu Zhang
JCI Insight. 2022 Feb 8; 7(3): e153191. Published online 2022 Feb 8. doi: 10.1172/jci.insight.153191
PMCID:
PMC8855833
AbstractArticlePDF–14M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward
Kyle E. Parker, Christian E. Pedersen, Adrian M. Gomez, Skylar M. Spangler, Marie C. Walicki, Shelley Y. Feng, Sarah L. Stewart, James M. Otis, Ream Al-Hasani, Jordan G. McCall, Kristina Sakers, Dionnet L. Bhatti, Bryan A. Copits, Robert W. Gereau, Thomas Jhou, Thomas J. Kash, Joseph D. Dougherty, Garret D. Stuber, Michael R. Bruchas
Cell. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell. 2019 Jul 25; 178(3): 653–671.e19. doi: 10.1016/j.cell.2019.06.034
PMCID:
PMC7001890
AbstractArticlePDF–3.1M
7.
Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists
Anika Mann, Lionel Moulédous, Carine Froment, Patrick R. O´Neill, Pooja Dasgupta, Thomas Günther, Gloria Brunori, Brigitte L. Kieffer, Lawrence Toll, Michael R. Bruchas, Nurulain T. Zaveri, Stefan Schulz
Sci Signal. Author manuscript; available in PMC 2019 Dec 27.
Published in final edited form as: Sci Signal. 2019 Mar 26; 12(574): eaau8072. Published online 2019 Mar 26. doi: 10.1126/scisignal.aau8072
PMCID:
PMC6934085
AbstractArticlePDF–3.2M
8.
Enhanced Spinal Nociceptin Receptor Expression Develops Morphine Tolerance and Dependence
Hiroshi Ueda, Makoto Inoue, Hiroshi Takeshima, Yoshikazu Iwasawa
J Neurosci. 2000 Oct 15; 20(20): 7640–7647. doi: 10.1523/JNEUROSCI.20-20-07640.2000
PMCID:
PMC6772876
AbstractArticlePDF–334K
9.
Blockade of Nociceptin/Orphanin FQ Receptor Signaling in Rat Substantia Nigra Pars Reticulata Stimulates Nigrostriatal Dopaminergic Transmission and Motor Behavior
Matteo Marti, Flora Mela, Carlo Veronesi, Remo Guerrini, Severo Salvadori, Mauro Federici, Nicola B. Mercuri, Anna Rizzi, Gianfranco Franchi, Lorenzo Beani, Clementina Bianchi, Michele Morari
J Neurosci. 2004 Jul 28; 24(30): 6659–6666. doi: 10.1523/JNEUROSCI.0987-04.2004
PMCID:
PMC6729727
AbstractArticlePDF–428K
10.
Blockade of Nociceptin/Orphanin FQ Transmission Attenuates Symptoms and Neurodegeneration Associated with Parkinson's Disease
Matteo Marti, Flora Mela, Martina Fantin, Silvia Zucchini, Jeffrey M. Brown, Jassir Witta, Manuela Di Benedetto, Beata Buzas, Rainer K. Reinscheid, Severo Salvadori, Remo Guerrini, Patrizia Romualdi, Sanzio Candeletti, Michele Simonato, Brian M. Cox, Michele Morari
J Neurosci. 2005 Oct 19; 25(42): 9591–9601. doi: 10.1523/JNEUROSCI.2546-05.2005
PMCID:
PMC6725738
AbstractArticlePDF–625K
11.
The Neuropeptide Nociceptin Is a Synaptically Released Endogenous Inhibitor of Hippocampal Long-Term Potentiation
Saknan Bongsebandhu-phubhakdi, Toshiya Manabe
J Neurosci. 2007 May 2; 27(18): 4850–4858. doi: 10.1523/JNEUROSCI.0876-07.2007
PMCID:
PMC6672088
AbstractArticlePDF–874K
12.
Tlx1/3 and Ptf1a Control the Expression of Distinct Sets of Transmitter and Peptide Receptor Genes in the Developing Dorsal Spinal Cord
Zhen Guo, Congling Zhao, Menggui Huang, Tianwen Huang, Mingran Fan, Zhiqin Xie, Ying Chen, Xiaolin Zhao, Guannan Xia, Junlan Geng, Leping Cheng
J Neurosci. 2012 Jun 20; 32(25): 8509–8520. doi: 10.1523/JNEUROSCI.6301-11.2012
PMCID:
PMC6620993
AbstractArticlePDF–5.6M
13.
Nociceptin/orphanin FQ inhibition with SB612111 ameliorates dextran sodium sulfate-induced colitis
Carsten Alt, Jennifer S. Lam, M. Travis Harrison, Kathleen M. Kershaw, Steven Samuelsson, Lawrence Toll, Annalisa D’Andrea
Eur J Pharmacol. Author manuscript; available in PMC 2019 Jun 19.
Published in final edited form as: Eur J Pharmacol. 2012 May 15; 683(1-3): 285–293. Published online 2012 Mar 16. doi: 10.1016/j.ejphar.2012.03.014
PMCID:
PMC6582657
AbstractArticlePDF–1.5M
14.
Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease
Ludovico Arcuri, Riccardo Viaro, Simone Bido, Francesco Longo, Mariangela Calcagno, Pierre-Olivier Fernagut, Nurulain T. Zaveri, Girolamo Calò, Erwan Bezard, Michele Morari
Neurobiol Dis. Author manuscript; available in PMC 2017 Aug 23.
Published in final edited form as: Neurobiol Dis. 2016 May; 89: 55–64. Published online 2016 Jan 22. doi: 10.1016/j.nbd.2016.01.016
PMCID:
PMC5567676
AbstractArticlePDF–2.9M
15.
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice
Derek Vang, Jinny A. Paul, Julia Nguyen, Huy Tran, Lucile Vincent, Dennis Yasuda, Nurulain T. Zaveri, Kalpna Gupta
Haematologica. 2015 Dec; 100(12): 1517–1525. doi: 10.3324/haematol.2015.128736
PMCID:
PMC4666327
AbstractArticlePDF–1.4M
16.
Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization
Akihiko Ozawa, Gloria Brunori, Daniela Mercatelli, Jinhua Wu, Andrea Cippitelli, Bende Zou, Xinmin (Simon) Xie, Melissa Williams, Nurulain T. Zaveri, Sarah Low, Grégory Scherrer, Brigitte L. Kieffer, Lawrence Toll
J Neurosci. 2015 Aug 19; 35(33): 11682–11693. doi: 10.1523/JNEUROSCI.5122-14.2015
PMCID:
PMC4540802
AbstractArticlePDF–3.4M
17.
Activation of nociceptin opioid peptide (NOP) receptor impairs contextual fear learning in mice through glutamatergic mechanisms
Celia Goeldner, Davids Reiss, Jürgen Wichmann, Brigitte L. Kieffer, Abdel-Mouttalib Ouagazzal
Neurobiol Learn Mem. Author manuscript; available in PMC 2015 Jun 26.
Published in final edited form as: Neurobiol Learn Mem. 2009 May; 91(4): 393–401. Published online 2009 Jan 22. doi: 10.1016/j.nlm.2008.12.001
PMCID:
PMC4482120
AbstractArticlePDF–1.0M
18.
Evidence of efficient stop codon readthrough in four mammalian genes
Gary Loughran, Ming-Yuan Chou, Ivaylo P. Ivanov, Irwin Jungreis, Manolis Kellis, Anmol M. Kiran, Pavel V. Baranov, John F. Atkins
Nucleic Acids Res. 2014 Aug 18; 42(14): 8928–8938. Published online 2014 Jul 10. doi: 10.1093/nar/gku608
PMCID:
PMC4132726
AbstractArticlePDF–2.3M
19.
A genomic atlas of mouse hypothalamic development
Tomomi Shimogori, Daniel A Lee, Ana Miranda-Angulo, Yanqin Yang, Hong Wang, Lizhi Jiang, Aya C Yoshida, Ayane Kataoka, Hiromi Mashiko, Marina Avetisyan, Lixin Qi, Jiang Qian, Seth Blackshaw
Nat Neurosci. Author manuscript; available in PMC 2014 Jun 24.
Published in final edited form as: Nat Neurosci. 2010 Jun; 13(6): 767–775. Published online 2010 May 2. doi: 10.1038/nn.2545
PMCID:
PMC4067769
AbstractArticlePDF–1.8M
20.
Amygdala-Dependent Fear Is Regulated by Oprl1 in Mice and Humans with PTSD
Raül Andero, Shaun P. Brothers, Tanja Jovanovic, Yen T. Chen, Hasib Salah-Uddin, Michael Cameron, Thomas D. Bannister, Lynn Almli, Jennifer S. Stevens, Bekh Bradley, Elisabeth B. Binder, Claes Wahlestedt, Kerry J. Ressler
Sci Transl Med. Author manuscript; available in PMC 2014 Jun 5.
Published in final edited form as: Sci Transl Med. 2013 Jun 5; 5(188): 188ra73. doi: 10.1126/scitranslmed.3005656
PMCID:
PMC3732318
AbstractArticlePDF–1.8M

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