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Items: 1 to 20 of 24

1.
Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants
James P Allen, Kathryn B Garber, Riley Perszyk, Cara T Khayat, Steven A Kell, Maki Kaneko, Catherine Quindipan, Sulagna Saitta, Roger L Ladda, Stacy Hewson, Michal Inbar-Feigenberg, Chitra Prasad, Asuri N Prasad, Leah Olewiler, Weiyi Mu, Liana S Rosenthal, Marcello Scala, Pasquale Striano, Federico Zara, Tyler W McCullock, Robin-Tobias Jauss, Johannes R Lemke, David M MacLean, Cheng Zhu, Hongjie Yuan, Scott J Myers, Stephen F Traynelis
Hum Mol Genet. 2024 Feb 15; 33(4): 355–373. Published online 2023 Nov 7. doi: 10.1093/hmg/ddad188
PMCID:
PMC10840383
AbstractArticlePDF–3.7M
2.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
3.
Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data
Robin Herbrechter, Nadine Hube, Raoul Buchholz, Andreas Reiner
Cell Mol Life Sci. 2021 Jul; 78(14): 5605–5630. Published online 2021 Jun 8. doi: 10.1007/s00018-021-03865-z
PMCID:
PMC8257547
AbstractArticlePDF–2.4M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Postsynaptic Density-93 Interacts with the δ2 Glutamate Receptor Subunit at Parallel Fiber Synapses
Katherine W. Roche, C. Dune Ly, Ronald S. Petralia, Ya-Xian Wang, Aaron W. McGee, David S. Bredt, Robert J. Wenthold
J Neurosci. 1999 May 15; 19(10): 3926–3934. doi: 10.1523/JNEUROSCI.19-10-03926.1999
PMCID:
PMC6782719
AbstractArticlePDF–769K
7.
A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Mol Cell. Author manuscript; available in PMC 2017 Oct 31.
Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004
PMCID:
PMC5663465
AbstractArticlePDF–2.1M
8.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
9.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
10.
GluD1 is a common altered player in neuronal differentiation from both MECP2-mutated and CDKL5-mutated iPS cells
Gabriella Livide, Tommaso Patriarchi, Mariangela Amenduni, Sonia Amabile, Dag Yasui, Eleonora Calcagno, Caterina Lo Rizzo, Giulia De Falco, Cristina Ulivieri, Francesca Ariani, Francesca Mari, Maria Antonietta Mencarelli, Johannes Wilhelm Hell, Alessandra Renieri, Ilaria Meloni
Eur J Hum Genet. 2015 Feb; 23(2): 195–201. Published online 2014 Jun 11. doi: 10.1038/ejhg.2014.81
PMCID:
PMC4172451
AbstractArticlePDF–882K
11.
Genome-Wide Association Study Identifies Novel Loci Associated With Concentrations of Four Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway: Results from the CHARGE Consortium
Jason H.Y. Wu, Rozenn N. Lemaitre, Ani Manichaikul, Weihua Guan, Toshiko Tanaka, Millennia Foy, Edmond K. Kabagambe, Luc Djousse, David Siscovick, Amanda M. Fretts, Catherine Johnson, Irena B. King, Bruce M. Psaty, Barbara McKnight, Stephen S. Rich, Yii-Der I. Chen, Jennifer A. Nettleton, Weihong Tang, Stefania Bandinelli, David R. Jacobs, Jr, Brian L. Browning, Cathy C. Laurie, Xiangjun Gu, Michael Y. Tsai, Lyn M. Steffen, Luigi Ferrucci, Myriam Fornage, Dariush Mozaffarian
Circ Cardiovasc Genet. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Circ Cardiovasc Genet. 2013 Apr; 6(2): 171–183. Published online 2013 Jan 29. doi: 10.1161/CIRCGENETICS.112.964619
PMCID:
PMC3891054
AbstractArticlePDF–1.9M
12.
A Genome-Wide Association Study Identifies New Susceptibility Loci for Esophageal Adenocarcinoma and Barrett’s Esophagus
David M. Levine, Weronica E. Ek, Rui Zhang, Xinxue Liu, Lynn Onstad, Cassandra Sather, Pierre Lao-Sirieix, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Nigel C. Bird, Laura J. Hardie, Liam J. Murray, Brian J. Reid, Wong-Ho Chow, Harvey A. Risch, Olof Nyrén, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, Alan G. Casson, Stephen Chanock, Patricia Harrington, Isabel Caldas, Irene Debiram-Beecham, Carlos Caldas, Nicholas K. Hayward, Paul Pharoah, Rebecca Fitzgerald, Stuart MacGregor, David C. Whiteman, Thomas L. Vaughan
Nat Genet. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: Nat Genet. 2013 Dec; 45(12): 1487–1493. Published online 2013 Oct 13. doi: 10.1038/ng.2796
PMCID:
PMC3840115
ArticlePDF–1.5M
13.
Genome-Wide Association Study of Survival in Patients with Pancreatic Adenocarcinoma
Chen Wu, Peter Kraft, Rachael Stolzenberg-Solomon, Emily Steplowski, Michelle Brotzman, Mousheng Xu, Poorva Mudgal, Laufey Amundadottir, Alan A. Arslan, H. Bas Bueno-de-Mesquita, Myron Gross, Kathy Helzlsouer, Eric J. Jacobs, Charles Kooperberg, Gloria M. Petersen, Wei Zheng, Demetrius Albanes, Marie-Christine Boutron-Ruault, Julie E. Buring, Federico Canzian, Guangwen Cao, Eric J. Duell, Joanne L. Elena, J. Michael Gaziano, Edward L. Giovannucci, Göran Hallmans, Amy Hutchinson, David J. Hunter, Mazda Jenab, Guoliang Jiang, Kay-Tee Khaw, Andrea LaCroix, Zhaoshen Li, Julie B. Mendelsohn, Salvatore Panico, Alpa V. Patel, Zhirong Qian, Howard Sesso, Hongbing Shen, Xiao-Ou Shu, Anne Tjonneland, Geoffrey S. Tobias, Dimitrios Trichopoulos, Jarmo Virtamo, Kala Visvanathan, Jean Wactawski-Wende, Chengfeng Wang, Kai Yu, Anne Zeleniuch-Jacquotte, Stephen Chanock, Robert Hoover, Patricia Hartge, Charles S. Fuchs, Dongxin Lin, Brian M. Wolpin
Gut. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Gut. 2014 Jan; 63(1): 10.1136/gutjnl-2012-303477. Published online 2012 Nov 24. doi: 10.1136/gutjnl-2012-303477
PMCID:
PMC3816124
AbstractArticlePDF–1.1M
14.
Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder
Pingxing Xie, Henry R. Kranzler, Can Yang, Hongyu Zhao, Lindsay A. Farrer, Joel Gelernter
Biol Psychiatry. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Biol Psychiatry. 2013 Nov 1; 74(9): 10.1016/j.biopsych.2013.04.013. Published online 2013 May 28. doi: 10.1016/j.biopsych.2013.04.013
PMCID:
PMC3810148
AbstractArticlePDF–319K
15.
Genetic variants associated with disordered eating
Tracey D Wade, Scott Gordon, Sarah Medland, Cynthia M. Bulik, Andrew C Heath, Grant W Montgomery, Nicholas G Martin
Int J Eat Disord. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Int J Eat Disord. 2013 Sep; 46(6): 594–608. Published online 2013 Apr 9. doi: 10.1002/eat.22133
PMCID:
PMC3775874
AbstractArticlePDF–2.1M
16.
Genome-wide Association Study of Periodontal Pathogen Colonization
K. Divaris, K.L. Monda, K.E. North, A.F. Olshan, E.M. Lange, K. Moss, S.P. Barros, J.D. Beck, S. Offenbacher
J Dent Res. 2012 Jul; 91(7 Suppl): S21–S28. doi: 10.1177/0022034512447951
PMCID:
PMC3383103
AbstractArticlePDF–2.0M
17.
Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein
Xiangbing Meng, Danlin Zhu, Shujie Yang, Xinjun Wang, Zhi Xiong, Yuping Zhang, Pavla Brachova, Kimberly K. Leslie
J Biol Chem. 2012 Feb 10; 287(7): 4485–4491. Published online 2011 Dec 23. doi: 10.1074/jbc.C111.291518
PMCID:
PMC3281628
AbstractArticlePDF–2.0M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Genetic Variants Associated With Cardiac Structure and Function: A Meta-analysis and Replication of Genome-wide Association Data
Dr. Ramachandran S. Vasan, Dr. Nicole L. Glazer, Dr. Janine F. Felix, Dr. Wolfgang Lieb, Dr. Philipp S. Wild, Dr. Stephan B. Felix, Dr. Norbert Watzinger, Dr. Martin G. Larson, Dr. Nicholas L. Smith, Dr. Abbas Dehghan, Dr. Anika Großhennig, Dr. Arne Schillert, Mr. Alexander Teumer, Dr. Reinhold Schmidt, Dr. Sekar Kathiresan, Dr. Thomas Lumley, Dr. Yurii S. Aulchenko, Dr. Inke R. König, Dr. Tanja Zeller, Dr. Georg Homuth, Dr. Maksim Struchalin, Dr. Jayashri Aragam, Dr. Joshua C. Bis, Dr. Fernando Rivadeneira, Dr. Jeanette Erdmann, Dr. Renate B. Schnabel, Dr. Marcus Dörr, Dr. Robert Zweiker, Dr. Lars Lind, Dr. Richard J. Rodeheffer, Dr. Karin Halina Greiser, Dr. Daniel Levy, Dr. Talin Haritunians, Dr. Jaap W. Deckers, Dr. Jan Stritzke, Dr. Karl J. Lackner, Dr. Uwe Völker, Dr. Erik Ingelsson, Dr. Iftikhar Kullo, Dr. Johannes Haerting, Dr. Christopher J. O’Donnell, Dr. Susan R. Heckbert, Dr. Bruno H. Stricker, Dr. Andreas Ziegler, Dr. Thorsten Reffelmann, Dr. Margaret M. Redfield, Dr. Karl Werdan, Dr. Gary F. Mitchell, Dr. Kenneth Rice, Dr. Donna K. Arnett, Dr. Albert Hofman, Dr. John S. Gottdiener, Dr. Andre G. Uitterlinden, Dr. Thomas Meitinger, Dr. Maria Blettner, Dr. Nele Friedrich, Dr. Thomas J. Wang, Dr. Bruce M. Psaty, Dr. Cornelia M. van Duijn, Dr. H.-Erich Wichmann, Dr. Thomas F. Munzel, Dr. Heyo K. Kroemer, Dr. Emelia J. Benjamin, Dr. Jerome I. Rotter, Dr. Jacqueline C. Witteman, Dr. Heribert Schunkert, Dr. Helena Schmidt, Dr. Henry Völzke, Dr. Stefan Blankenberg
JAMA. Author manuscript; available in PMC 2010 Nov 8.
Published in final edited form as: JAMA. 2009 Jul 8; 302(2): 168–178. doi: 10.1001/jama.2009.978-a
PMCID:
PMC2975567
AbstractArticlePDF–1.3M
20.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M

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