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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice
P. Poursharifi, C. Schmitt, I. Chenier, Y.H. Leung, A.K. Oppong, Y. Bai, L.-L. Klein, A. Al-Mass, R. Lussier, M. Abu-Farha, J. Abubaker, F. Al-Mulla, M.-L. Peyot, S.R.M. Madiraju, M. Prentki
Mol Metab. 2023 Dec; 78: 101822. Published online 2023 Oct 12. doi: 10.1016/j.molmet.2023.101822
PMCID:
PMC10622714
AbstractArticlePDF–3.3M
3.
The serine hydrolase ABHD6 controls survival and thermally induced seizures in a mouse model of Dravet syndrome
Ruth Westenbroek, Joshua Kaplan, Katie Viray, Nephi Stella
Neurobiol Dis. Author manuscript; available in PMC 2023 Jul 10.
Published in final edited form as: Neurobiol Dis. 2023 May; 180: 106099. Published online 2023 Mar 27. doi: 10.1016/j.nbd.2023.106099
PMCID:
PMC10332637
AbstractArticlePDF–1.3M
4.
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
Cristina Miralpeix, Ana Cristina Reguera, Anna Fosch, Maria Casas, Jaume Lillo, Gemma Navarro, Rafael Franco, Josefina Casas, Stephen P.H. Alexander, Núria Casals, Rosalía Rodríguez‐Rodríguez
Br J Pharmacol. 2021 Apr; 178(7): 1507–1523. Published online 2021 Feb 12. doi: 10.1111/bph.15377
PMCID:
PMC9328656
AbstractArticlePDF–8.5M
5.
ABHD6 Controls Amphetamine-Stimulated Hyperlocomotion: Involvement of CB1 Receptors
Liting Deng, Katie Viray, Simar Singh, Ben Cravatt, Nephi Stella
Cannabis Cannabinoid Res. April 2022; 7(2): 188–198. Published online 2022 Apr 19. doi: 10.1089/can.2021.0066
PMCID:
PMC9070749
AbstractArticlePDF–541K
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Adipose ABHD6 regulates tolerance to cold and thermogenic programs
Pegah Poursharifi, Camille Attané, Yves Mugabo, Anfal Al-Mass, Anindya Ghosh, Clémence Schmitt, Shangang Zhao, Julian Guida, Roxane Lussier, Heidi Erb, Isabelle Chenier, Marie-Line Peyot, Erik Joly, Christophe Noll, André C. Carpentier, S.R. Murthy Madiraju, Marc Prentki
JCI Insight. 2020 Dec 17; 5(24): e140294. Published online 2020 Dec 17. doi: 10.1172/jci.insight.140294
PMCID:
PMC7819748
AbstractArticlePDF–27M
8.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
9.
Identification of α,β-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells
Annelot C. M. van Esbroeck, Vasudev Kantae, Xinyu Di, Tom van der Wel, Hans den Dulk, Anna F. Stevens, Simar Singh, Alexander T. Bakker, Bogdan I. Florea, Nephi Stella, Herman S. Overkleeft, Thomas Hankemeier, Mario van der Stelt
Front Mol Neurosci. 2019; 12: 286. Published online 2019 Nov 26. doi: 10.3389/fnmol.2019.00286
PMCID:
PMC6901982
AbstractArticlePDF–2.4M
10.
Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
J Lipid Res. 2019 May; 60(5): 1020–1031. Published online 2019 Mar 20. doi: 10.1194/jlr.M093351
PMCID:
PMC6495172
AbstractArticlePDF–1.4M
11.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
12.
α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
Mengping Wei, Jian Zhang, Moye Jia, Chaojuan Yang, Yunlong Pan, Shuaiqi Li, Yiwen Luo, Junyuan Zheng, Jianguo Ji, Jianguo Chen, Xinli Hu, Jingwei Xiong, Yun Shi, Chen Zhang
Proc Natl Acad Sci U S A. 2016 May 10; 113(19): E2695–E2704. Published online 2016 Apr 25. doi: 10.1073/pnas.1524589113
PMCID:
PMC4868484
AbstractArticlePDF–3.0M
13.
α/β-Hydrolase domain-6 and saturated long chain monoacylglycerol regulate insulin secretion promoted by both fuel and non-fuel stimuli
Shangang Zhao, Pegah Poursharifi, Yves Mugabo, Emily J. Levens, Kevin Vivot, Camille Attane, Jose Iglesias, Marie-line Peyot, Erik Joly, S.R. Murthy Madiraju, Marc Prentki
Mol Metab. 2015 Dec; 4(12): 940–950. Published online 2015 Oct 8. doi: 10.1016/j.molmet.2015.09.012
PMCID:
PMC4731734
AbstractArticlePDF–2.2M
14.
α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate
Maria A. Pribasnig, Irina Mrak, Gernot F. Grabner, Ulrike Taschler, Oskar Knittelfelder, Barbara Scherz, Thomas O. Eichmann, Christoph Heier, Lukas Grumet, Jakob Kowaliuk, Matthias Romauch, Stefan Holler, Felix Anderl, Heimo Wolinski, Achim Lass, Rolf Breinbauer, Gunther Marsche, J. Mark Brown, Robert Zimmermann
J Biol Chem. 2015 Dec 11; 290(50): 29869–29881. Published online 2015 Oct 21. doi: 10.1074/jbc.M115.669168
PMCID:
PMC4705992
AbstractArticlePDF–2.0M
15.
Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture
Katarzyna Malenczyk, Erik Keimpema, Fabiana Piscitelli, Daniela Calvigioni, Peyman Björklund, Kenneth Mackie, Vincenzo Di Marzo, Tomas G. M. Hökfelt, Agnieszka Dobrzyn, Tibor Harkany
Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): E6185–E6194. Published online 2015 Oct 22. doi: 10.1073/pnas.1519040112
PMCID:
PMC4653226
AbstractArticlePDF–2.6M
16.
The Serine Hydrolase ABHD6 is a Critical Regulator of the Metabolic Syndrome
Gwynneth Thomas, Jenna L. Betters, Caleb C. Lord, Amanda L. Brown, Stephanie Marshall, Daniel Ferguson, Janet Sawyer, Matthew A. Davis, John T. Melchior, Lawrence C. Blume, Allyn C. Howlett, Pavlina T. Ivanova, Stephen B. Milne, David S. Myers, Irina Mrak, Vera Leber, Christoph Heier, Ulrike Taschler, Jacqueline L. Blankman, Benjamin F. Cravatt, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Robert Zimmermann, H. Alex Brown, J. Mark Brown
Cell Rep. Author manuscript; available in PMC 2013 Nov 19.
Published in final edited form as: Cell Rep. 2013 Oct 31; 5(2): 10.1016/j.celrep.2013.08.047. Published online 2013 Oct 3. doi: 10.1016/j.celrep.2013.08.047
PMCID:
PMC3833083
AbstractArticlePDF–2.4M
17.
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6
Mireille Alhouayek, Julien Masquelier, Patrice D. Cani, Didier M. Lambert, Giulio G. Muccioli
Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43): 17558–17563. Published online 2013 Oct 7. doi: 10.1073/pnas.1314017110
PMCID:
PMC3808642
AbstractArticlePDF–989K
18.
EUKARYOTIC RIBONUCLEASE P: A Plurality of Ribonucleoprotein Enzymes
Shaohua Xiao, Felicia Scott, Carol A. Fierke, David R. Engelke
Annu Rev Biochem. Author manuscript; available in PMC 2013 Sep 3.
Published in final edited form as: Annu Rev Biochem. 2002; 71: 165–189. Published online 2001 Nov 9. doi: 10.1146/annurev.biochem.71.110601.135352
PMCID:
PMC3759807
AbstractArticlePDF–916K
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Dual Inhibition of α/β-Hydrolase Domain 6 and Fatty Acid Amide Hydrolase Increases Endocannabinoid Levels in Neurons
William R. Marrs, Eric A. Horne, Silvia Ortega-Gutierrez, Jose Antonio Cisneros, Cong Xu, Yi Hsing Lin, Giulio G. Muccioli, Maria L. Lopez-Rodriguez, Nephi Stella
J Biol Chem. 2011 Aug 19; 286(33): 28723–28728. Published online 2011 Jun 10. doi: 10.1074/jbc.M110.202853
PMCID:
PMC3190680
AbstractArticlePDF–862K

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