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Select item 111307111.

NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation

Tao Yu, Dan Hou, Jiaqi Zhao, Xuan Lu, Wendy K. Greentree, Qian Zhao, Min Yang, Don-Gerard Conde, Maurine E. Linder, Hening Lin

Cell Rep. Author manuscript; available in PMC 2024 May 28.

Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114070. Published online 2024 Apr 6. doi: 10.1016/j.celrep.2024.114070

PMCID:: PMC11130711

Abstract Article PDF–3.0M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107165903.

Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy

Tanya A. Baldwin, James P. Teuber, Yasuhide Kuwabara, Araskumar Subramani, Suh-Chin J. Lin, Onur Kanisicak, Ronald J. Vagnozzi, Weiqi Zhang, Matthew J. Brody, Jeffery D. Molkentin

J Biol Chem. 2023 Dec; 299(12): 105426. Published online 2023 Nov 3. doi: 10.1016/j.jbc.2023.105426

PMCID:: PMC10716590

Abstract Article PDF–1.7M

Select item 105586854.

IFI27 Integrates Succinate and Fatty Acid Oxidation to Promote Adipocyte Thermogenic Adaption

Xuan Cui, Haojie Liu, Ting Shi, Qingwen Zhao, Feiyan Li, Wenjing Lv, Chao Yu, Haiyan Huang, Qi‐Qun Tang, Dongning Pan

Adv Sci (Weinh) 2023 Oct; 10(28): 2301855. Published online 2023 Aug 6. doi: 10.1002/advs.202301855

PMCID:: PMC10558685

Abstract Article PDF–5.6M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 57909596.

The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection

Shaohui Wang, Kevin R. Mott, Marianne Cilluffo, Casey L. Kilpatrick, Shoko Murakami, Alexander V. Ljubimov, Konstantin G. Kousoulas, Sita Awasthi, Bernhard Luscher, Homayon Ghiasi

J Virol. 2018 Feb 15; 92(4): e01599-17. Prepublished online 2017 Nov 29. Published online 2018 Jan 30. doi: 10.1128/JVI.01599-17

PMCID:: PMC5790959

Abstract Article PDF–1.8M

Select item 53384077.

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry

Jennifer Greaves, Kevin R. Munro, Stuart C. Davidson, Matthieu Riviere, Justyna Wojno, Terry K. Smith, Nicholas C. O. Tomkinson, Luke H. Chamberlain

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1365–E1374. Published online 2017 Feb 6. doi: 10.1073/pnas.1612254114

PMCID:: PMC5338407

Abstract Article PDF–1.4M

Select item 53141928.

DHHC7 Palmitoylates Glucose Transporter 4 (Glut4) and Regulates Glut4 Membrane Translocation

Keyong Du, Shoko Murakami, Yingmin Sun, Casey L. Kilpatrick, Bernhard Luscher

J Biol Chem. 2017 Feb 17; 292(7): 2979–2991. Published online 2017 Jan 5. doi: 10.1074/jbc.M116.747139

PMCID:: PMC5314192

Abstract Article PDF–3.5M

Select item 52071639.

Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-β (SERZ-β)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice

Casey L. Kilpatrick, Shoko Murakami, Mengyang Feng, Xia Wu, Rachnanjali Lal, Gong Chen, Keyong Du, Bernhard Luscher

J Biol Chem. 2016 Dec 30; 291(53): 27371–27386. Published online 2016 Nov 14. doi: 10.1074/jbc.M116.732768

PMCID:: PMC5207163

Abstract Article PDF–3.4M

Select item 508772410.

Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization

Joseph Murphy, Saravanan Kolandaivelu

J Biol Chem. 2016 Oct 28; 291(44): 23036–23046. Published online 2016 Sep 9. doi: 10.1074/jbc.M116.742767

PMCID:: PMC5087724

Abstract Article PDF–991K

Select item 498592911.

ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation

Patricia Marie-Jeanne Lievens, Tatiana Kuznetsova, Gaga Kochlamazashvili, Fabrizia Cesca, Natalya Gorinski, Dalia Abdel Galil, Volodimir Cherkas, Natalia Ronkina, Juri Lafera, Matthias Gaestel, Evgeni Ponimaskin, Alexander Dityatev

Mol Cell Biol. 2016 Sep 1; 36(17): 2208–2225. Prepublished online 2016 May 31. Published online 2016 Aug 12. doi: 10.1128/MCB.00144-16

PMCID:: PMC4985929

Abstract Article PDF–3.1M

Select item 470593212.

The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc

Colin D. Gottlieb, Sheng Zhang, Maurine E. Linder

J Biol Chem. 2015 Dec 4; 290(49): 29259–29269. Published online 2015 Oct 20. doi: 10.1074/jbc.M115.691147

PMCID:: PMC4705932

Abstract Article PDF–1.2M

Select item 424419713.

The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity

Kimon Lemonidis, Oforiwa A. Gorleku, Maria C. Sanchez-Perez, Christopher Grefen, Luke H. Chamberlain

Mol Biol Cell. 2014 Dec 1; 25(24): 3870–3883. doi: 10.1091/mbc.E14-06-1169

PMCID:: PMC4244197

Abstract Article PDF–8.2M

Select item 396495514.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 382936915.

Oligomerization of DHHC Protein S-Acyltransferases

Jianbin Lai, Maurine E. Linder

J Biol Chem. 2013 Aug 2; 288(31): 22862–22870. Published online 2013 Jun 22. doi: 10.1074/jbc.M113.458794

PMCID:: PMC3829369

Abstract Article PDF–920K

Select item 370768516.

In Silico Screening for Palmitoyl Substrates Reveals a Role for DHHC1/3/10 (zDHHC1/3/11)-mediated Neurochondrin Palmitoylation in Its Targeting to Rab5-positive Endosomes

Shinichiro Oku, Naoki Takahashi, Yuko Fukata, Masaki Fukata

J Biol Chem. 2013 Jul 5; 288(27): 19816–19829. Published online 2013 May 16. doi: 10.1074/jbc.M112.431676

PMCID:: PMC3707685

Abstract Article PDF–4.4M

Select item 343984517.

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith

Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130

PMCID:: PMC3439845

Abstract Article PDF–1.4M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253419.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 288223320.

Palmitoylation and Membrane Interactions of the Neuroprotective Chaperone Cysteine-string Protein

Jennifer Greaves, Christine Salaun, Yuko Fukata, Masaki Fukata, Luke H. Chamberlain

J Biol Chem. 2008 Sep 5; 283(36): 25014–25026. doi: 10.1074/jbc.M802140200

PMCID:: PMC2882233

Abstract Article PDF–889K

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