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Select item 111902251.

CD8⁺ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB

Kelsey B. Bennion, Danya Liu, Abdelhameed S. Dawood, Megan M. Wyatt, Katie L. Alexander, Mohamed S. Abdel-Hakeem, Chrystal M. Paulos, Mandy L. Ford

Nat Commun. 2024; 15: 5280. Published online 2024 Jun 20. doi: 10.1038/s41467-024-49475-8

PMCID:: PMC11190225

Abstract Article PDF–2.6M

Select item 111021382.

Unveiling the hidden role of the interaction between CD36 and FcγRIIb: implications for autoimmune disorders

Chenfei He, Guoying Hua, Yong Liu, Shuijie Li

Cell Mol Biol Lett. 2024; 29: 76. Published online 2024 May 18. doi: 10.1186/s11658-024-00593-7

PMCID:: PMC11102138

Abstract Article PDF–1.5M

Select item 110341353.

Elk1 enhances inflammatory cell infiltration and exacerbates acute lung injury/acute respiratory distress syndrome by suppressing Fcgr2b transcription

Shiyou Wei, Dandan Ling, Jingui Zhong, Rui Chang, Xinyu Ling, Zhigang Chen, Ruowang Duan

Mol Med. 2024; 30: 53. Published online 2024 Apr 22. doi: 10.1186/s10020-024-00820-z

PMCID:: PMC11034135

Abstract Article PDF–7.5M

Select item 109117034.

FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment

David A. Knorr, Lucas Blanchard, Rom S. Leidner, Shawn M. Jensen, Ryan Meng, Andrew Jones, Carmen Ballesteros-Merino, Richard B. Bell, Maria Baez, Alessandra Marino, David Sprott, Carlo B. Bifulco, Brian Piening, Rony Dahan, Juan C. Osorio, Bernard A. Fox, Jeffrey V. Ravetch

Cancer Immunol Res. 2024 Mar 4; 12(3): 322–333. Published online 2023 Dec 26. doi: 10.1158/2326-6066.CIR-23-0389

PMCID:: PMC10911703

Abstract Article PDF–3.3M

Select item 107073935.

Lipopolysaccharide Impedes Bone Repair in FcγRIIB-Deficient Mice

Sirikanda Jantaboon, Nithidol Sakunrangsit, Parichart Toejing, Asada Leelahavanichkul, Prapaporn Pisitkun, Matthew B. Greenblatt, Sutada Lotinun

Int J Mol Sci. 2023 Dec; 24(23): 16944. Published online 2023 Nov 29. doi: 10.3390/ijms242316944

PMCID:: PMC10707393

Abstract Article PDF–5.1M

Select item 106198176.

Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmp^gt/gt mouse model of slowly progressing liver fibrosis

Milton Boaheng Antwi, Gianina Dumitriu, Jaione Simón-Santamaria, Javier Sánchez Romano, Ruomei Li, Bård Smedsrød, Anders Vik, Winnie Eskild, Karen Kristine Sørensen

PLoS One. 2023; 18(11): e0293526. Published online 2023 Nov 1. doi: 10.1371/journal.pone.0293526

PMCID:: PMC10619817

Abstract Article PDF–7.5M

Select item 105828877.

C-reactive protein impairs immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma

Jinxing Jiang, Ziyi Peng, Junying Wang, Mengping Chen, Yike Wan, Honghui Huang, Zhiqiang Liu, Jingya Wang, Jian Hou

J Immunother Cancer. 2023; 11(10): e007593. Published online 2023 Oct 15. doi: 10.1136/jitc-2023-007593

Correction in:: J Immunother Cancer. 2023; 11(12): e007593corr1.

PMCID:: PMC10582887

Abstract Article PDF–5.1M

Select item 105248698.

IgG:FcγRIIb signals block effector programs of IgE:FcεRI-activated mast cells but spare survival pathways

Cynthia Kanagaratham, Tahereh Derakhshan, Yasmeen S. El Ansari, Kameryn N. Furiness, Eleanor Hollers, Mats Keldsen, Hans C. Oettgen, Daniel F. Dwyer

J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2023 Aug; 152(2): 453–468. Published online 2023 Apr 6. doi: 10.1016/j.jaci.2023.03.027

PMCID:: PMC10524869

Abstract Article PDF–3.0M

Select item 103943799.

Plasmodium curtails autoimmune nephritis via lasting bone marrow alterations, independent of hemozoin accumulation

Laura Amo, Hemanta K. Kole, Bethany Scott, Chen-Feng Qi, Ludmila Krymskaya, Hongsheng Wang, Louis H. Miller, Chris J. Janse, Silvia Bolland

Front Immunol. 2023; 14: 1192819. Published online 2023 Jul 19. doi: 10.3389/fimmu.2023.1192819

PMCID:: PMC10394379

Abstract Article PDF–6.4M

Select item 1036616410.

Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents

Shingo Umemoto, Rika Nakahashi-Ouchida, Yoshikazu Yuki, Shiho Kurokawa, Tomonori Machita, Yohei Uchida, Hiromi Mori, Tomoyuki Yamanoue, Takehiko Shibata, Shin-ichi Sawada, Kazuya Ishige, Takashi Hirano, Kohtaro Fujihashi, Kazunari Akiyoshi, Yosuke Kurashima, Daisuke Tokuhara, Peter B Ernst, Masashi Suzuki, Hiroshi Kiyono

NPJ Vaccines. 2023; 8: 106. Published online 2023 Jul 24. doi: 10.1038/s41541-023-00700-3

PMCID:: PMC10366164

Abstract Article PDF–2.7M

Select item 1036442311.

Knockdown of DEC2 expression inhibits the proliferation of mesangial cells through suppressed glycolysis and p38 MAPK/Erk pathway in lupus nephritis

Huimeng Qi, Li Xu, Qiang Liu

Mol Med. 2023; 29: 99. Published online 2023 Jul 24. doi: 10.1186/s10020-023-00672-z

Correction in:: Mol Med. 2023; 29: 124.

PMCID:: PMC10364423

Abstract Article PDF–5.5M

Select item 1019144112.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 991173313.

FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells

Qingnan Zhao, Jiemiao Hu, Lingyuan Kong, Shan Jiang, Xiangjun Tian, Jing Wang, Rintaro Hashizume, Zhiliang Jia, Natalie Wall Fowlkes, Jun Yan, Xueqing Xia, Sofia F. Yi, Long Hoang Dao, David Masopust, Amy B. Heimberger, Shulin Li

Nat Commun. 2023; 14: 735. Published online 2023 Feb 10. doi: 10.1038/s41467-023-36430-2

PMCID:: PMC9911733

Abstract Article PDF–9.3M

Select item 959252614.

Establishment of fetomaternal tolerance through glycan-mediated B cell suppression

G. Rizzuto, J. F. Brooks, S. T. Tuomivaara, T. I. McIntyre, S. Ma, D. Rideaux, J. Zikherman, S. J. Fisher, A. Erlebacher

Nature. Author manuscript; available in PMC 2022 Oct 25.

Published in final edited form as: Nature. 2022 Mar; 603(7901): 497–502. Published online 2022 Mar 2. doi: 10.1038/s41586-022-04471-0

PMCID:: PMC9592526

Abstract Article PDF–4.4M

Select item 937576715.

Two major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance

Qijing Li, Jianghong Zhong, Huqiao Luo, Vilma Urbonaviciute, Zhongwei Xu, Chang He, Rikard Holmdahl

Cell Mol Life Sci. 2022 Sep; 79(9): 482. Published online 2022 Aug 14. doi: 10.1007/s00018-022-04501-0

PMCID:: PMC9375767

Abstract Article PDF–4.6M

Select item 869289416.

FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape

Lei Wu, Yanquan Xu, Huakan Zhao, Yu Zhou, Yu Chen, Shuai Yang, Juan Lei, Jiangang Zhang, Jingchun Wang, Yongzhong Wu, Yongsheng Li

Theranostics. 2022; 12(2): 842–858. Published online 2022 Jan 1. doi: 10.7150/thno.66575

PMCID:: PMC8692894

Abstract Article PDF–3.9M

Select item 859917117.

C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation

Hai-Yun Li, Zhao-Ming Tang, Zhe Wang, Jian-Min Lv, Xiao-Ling Liu, Yu-Lin Liang, Bin Cheng, Ning Gao, Shang-Rong Ji, Yi Wu

Cell Mol Gastroenterol Hepatol. 2022; 13(1): 289–307. Published online 2021 Sep 16. doi: 10.1016/j.jcmgh.2021.09.003

PMCID:: PMC8599171

Abstract Article PDF–8.7M

Select item 841004318.

Monoallelic IRF5 deficiency in B cells prevents murine lupus

Alex Pellerin, Kei Yasuda, Abraham Cohen-Bucay, Vanessa Sandra, Prachi Shukla, Barry K. Horne Jr, Kerstin Nündel, Gregory A. Viglianti, Yao Xie, Ulf Klein, Ying Tan, Ramon G. Bonegio, Ian R. Rifkin

JCI Insight. 2021 Aug 9; 6(15): e141395. Published online 2021 Aug 9. doi: 10.1172/jci.insight.141395

PMCID:: PMC8410043

Abstract Article PDF–6.7M

Select item 826907319.

Acute Kidney Injury Induced Lupus Exacerbation Through the Enhanced Neutrophil Extracellular Traps (and Apoptosis) in Fcgr2b Deficient Lupus Mice With Renal Ischemia Reperfusion Injury

Wilasinee Saisorn, Supichcha Saithong, Pornpimol Phuengmaung, Kanyarat Udompornpitak, Thansita Bhunyakarnjanarat, Peerapat Visitchanakun, Awirut Chareonsappakit, Prapaporn Pisitkun, Direkrit Chiewchengchol, Asada Leelahavanichkul

Front Immunol. 2021; 12: 669162. Published online 2021 Jun 24. doi: 10.3389/fimmu.2021.669162