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Select item 110307301.

Expression of CD13/aminopeptidase N in precursor B-cell leukemia: role in growth regulation of B cells

Ankit Saxena, Ambak Rai, Vinod Raina, Tulika Seth, Dipendra Kumar Mitra

Cancer Immunol Immunother. 2010 Jan; 59(1): 125–135. Published online 2009 Jun 28. doi: 10.1007/s00262-009-0731-6

PMCID:: PMC11030730

Abstract Article PDF–1.1M

Select item 109604152.

CD13 expression affects glioma patient survival and influences key functions of human glioblastoma cell lines in vitro

Wenying Zhang, Anne Blank, Irina Kremenetskaia, Anja Nitzsche, Güliz Acker, Peter Vajkoczy, Susan Brandenburg

BMC Cancer. 2024; 24: 369. Published online 2024 Mar 22. doi: 10.1186/s12885-024-12113-z

PMCID:: PMC10960415

Abstract Article PDF–11M

Select item 106043253.

Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18

Laura Díaz-Alvarez, Mariana Esther Martínez-Sánchez, Eleanor Gray, Erandi Pérez-Figueroa, Enrique Ortega

Biomolecules. 2023 Oct; 13(10): 1488. Published online 2023 Oct 6. doi: 10.3390/biom13101488

PMCID:: PMC10604325

Abstract Article PDF–3.5M

Select item 105660994.

CD13 facilitates immune cell migration and aggravates acute injury but promotes chronic post-stroke recovery

Justin N. Nguyen, Eric C. Mohan, Gargee Pandya, Uzma Ali, Chunfeng Tan, Julia K. Kofler, Linda Shapiro, Sean P. Marrelli, Anjali Chauhan

J Neuroinflammation. 2023; 20: 232. Published online 2023 Oct 10. doi: 10.1186/s12974-023-02918-3

PMCID:: PMC10566099

Abstract Article PDF–5.4M

Select item 101669505.

Reduced expression of alanyl aminopeptidase is a robust biomarker of non‐familial adenomatous polyposis and non‐hereditary nonpolyposis colorectal cancer syndrome early‐onset colorectal cancer

Ye Jin Ha, Yun Jae Shin, Ka Hee Tak, Jong Lyul Park, Jeong Hwan Kim, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seon Young Kim, Jin Cheon Kim

Cancer Med. 2023 Apr; 12(8): 10091–10104. Published online 2023 Feb 7. doi: 10.1002/cam4.5675

PMCID:: PMC10166950

Abstract Article PDF–7.5M

Select item 96500556.

Soluble ANPEP Released From Human Astrocytes as a Positive Regulator of Microglial Activation and Neuroinflammation: Brain Renin–Angiotensin System in Astrocyte–Microglia Crosstalk

Jong-Heon Kim, Ruqayya Afridi, Eunji Cho, Jong Hyuk Yoon, Yong-Hyun Lim, Ho-Won Lee, Hoon Ryu, Kyoungho Suk

Mol Cell Proteomics. 2022 Nov; 21(11): 100424. Published online 2022 Oct 8. doi: 10.1016/j.mcpro.2022.100424

PMCID:: PMC9650055

Abstract Article PDF–3.0M

Select item 95355197.

Abnormal CD13/HLA-DR Expression Pattern on Myeloblasts Predicts Development of Myeloid Neoplasia in Patients With Clonal Cytopenia of Undetermined Significance

Dragan Jevremovic, Ahmad Nanaa, Susan M Geyer, Michael Timm, Haya Azouz, Cynthia Hengel, Alexander Reberg, Rong He, David Viswanatha, Mohamad E Salama, Min Shi, Horatiu Olteanu, Pedro Horna, Gregory Otteson, Patricia T Greipp, Zhuoer Xie, Hassan B Alkhateeb, William Hogan, Mark Litzow, Mrinal M Patnaik, Mithun Shah, Aref Al-Kali, Phuong L Nguyen

Am J Clin Pathol. 2022 Oct; 158(4): 530–536. Published online 2022 Aug 8. doi: 10.1093/ajcp/aqac083

PMCID:: PMC9535519

Abstract Article PDF–551K

Select item 92792858.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92316239.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917548210.

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression

Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma

BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4

PMCID:: PMC9175482

Abstract Article PDF–15M

Select item 874895811.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 855290712.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 833899313.

CD13 orients the apical-basal polarity axis necessary for lumen formation

Li-Ting Wang, Abira Rajah, Claire M. Brown, Luke McCaffrey

Nat Commun. 2021; 12: 4697. Published online 2021 Aug 4. doi: 10.1038/s41467-021-24993-x

PMCID:: PMC8338993

Abstract Article PDF–5.6M

Select item 814419514.

CD13 is a critical regulator of cell–cell fusion in osteoclastogenesis

Mallika Ghosh, Tomislav Kelava, Ivana Vrhovac Madunic, Ivo Kalajzic, Linda H. Shapiro

Sci Rep. 2021; 11: 10736. Published online 2021 May 24. doi: 10.1038/s41598-021-90271-x

PMCID:: PMC8144195

Abstract Article PDF–4.1M

Select item 812686215.

SIK2 orchestrates actin-dependent host response upon Salmonella infection

Marcel Hahn, Adriana Covarrubias-Pinto, Lina Herhaus, Shankha Satpathy, Kevin Klann, Keith B. Boyle, Christian Münch, Krishnaraj Rajalingam, Felix Randow, Chunaram Choudhary, Ivan Dikic

Proc Natl Acad Sci U S A. 2021 May 11; 118(19): e2024144118. Published online 2021 May 4. doi: 10.1073/pnas.2024144118

PMCID:: PMC8126862

Abstract Article PDF–3.0M

Select item 809474716.

Reduced Activity of CD13/Aminopeptidase N (APN) in Aggressive Meningiomas Is Associated with Increased Levels of SPARC

Christian Mawrin, Carmen Wolke, Daniela Haase, Sabine Krüger, Raimund Firsching, Gerburg Keilhoff, Werner Paulus, David H. Gutmann, Anita Lal, Uwe Lendeckel

Brain Pathol. 2010 Jan; 20(1): 200–210. Published online 2009 Feb 19. doi: 10.1111/j.1750-3639.2009.00267.x

PMCID:: PMC8094747

Abstract Article PDF–424K

Select item 797284117.

In Vivo Molecular Imaging of the Efficacy of Aminopeptidase N (APN/CD13) Receptor Inhibitor Treatment on Experimental Tumors Using ⁶⁸Ga-NODAGA-c(NGR) Peptide

Adrienn Kis, Noémi Dénes, Judit P. Szabó, Viktória Arató, Lívia Beke, Orsolya Matolay, Kata Nóra Enyedi, Gábor Méhes, Gábor Mező, Péter Bai, István Kertész, György Trencsényi

Biomed Res Int. 2021; 2021: 6642973. Published online 2021 Mar 10. doi: 10.1155/2021/6642973

PMCID:: PMC7972841

Abstract Article PDF–1.0M

Select item 765186218.

TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway

Shiyu Chen, Zhiwei He, Changhao Zhu, Yanqing Liu, Lin Li, Lu Deng, Jun Wang, Chao Yu, Chengyi Sun

Front Oncol. 2020; 10: 554787. Published online 2020 Oct 16. doi: 10.3389/fonc.2020.554787

PMCID:: PMC7651862

Abstract Article PDF–5.4M

Select item 756509119.

Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases

Weronika Wanat, Michał Talma, Błażej Dziuk, Paweł Kafarski

Biomolecules. 2020 Sep; 10(9): 1319. Published online 2020 Sep 14. doi: 10.3390/biom10091319

PMCID:: PMC7565091

Abstract Article PDF–2.6M

Select item 724904320.

APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway

Mengying Zhai, Zixia Yang, Chenrui Zhang, Jinping Li, Jing Jia, Lingyi Zhou, Rong Lu, Zhi Yao, Zheng Fu

Cell Death Dis. 2020 May; 11(5): 396. Published online 2020 May 26. doi: 10.1038/s41419-020-2610-1

PMCID:: PMC7249043

Abstract Article PDF–9.1M

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