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Select item 110396121.

ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder

Matthias Przyklenk, Shreya Karmacharya, Debora Bonasera, Arthur-Lauri Pasanen-Zentz, Stanislav Kmoch, Mats Paulsson, Raimund Wagener, Gianmaria Liccardi, Alvise Schiavinato

Sci Rep. 2024; 14: 9321. Published online 2024 Apr 23. doi: 10.1038/s41598-024-59901-y

PMCID:: PMC11039612

Abstract Article PDF–6.6M

Select item 110298842.

Tumor endothelial marker 8 expression levels in dendritic cell-based cancer vaccines are related to clinical outcome

Franco Maria Venanzi, Massimiliano Petrini, Laura Fiammenghi, Elisabetta Bolli, Anna Maria Granato, Laura Ridolfi, Federica Gabrielli, Alessandra Barucca, Antonio Concetti, Ruggero Ridolfi, Angela Riccobon

Cancer Immunol Immunother. 2010 Jan; 59(1): 27–34. Published online 2009 May 7. doi: 10.1007/s00262-009-0717-4

PMCID:: PMC11029884

Abstract Article PDF–444K

Select item 103232523.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 94408114.

ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell

Tingting Jin, Zhaojun Zhang, Yuanyuan Han, Di Li, Juan Liu, Minmin Jiang, Ryo Kurita, Yukio Nakamura, Fangfang Hu, Xiangdong Fang, Shengwen Huang, Zhaolin Sun

Dis Markers. 2022; 2022: 1226697. Published online 2022 Aug 27. doi: 10.1155/2022/1226697

PMCID:: PMC9440811

Abstract Article PDF–4.0M

Select item 93568485.

Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway

Tingting Jin, Zhaojun Zhang, Yuanyuan Han, Di Li, Juan Liu, Minmin Jiang, Junwei Zhu, Ryo Kurita, Yukio Nakamura, Fangfang Hu, Yongjie Xu, Xiangdong Fang, Shengwen Huang, Zhaolin Sun

J Immunol Res. 2022; 2022: 8440422. Published online 2022 Jul 30. doi: 10.1155/2022/8440422

PMCID:: PMC9356848

Abstract Article PDF–3.3M

Select item 92316236.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 87489587.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 85138538.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 84402879.

N-Myc promotes angiogenesis and therapeutic resistance of prostate cancer by TEM8

Mingfeng Li, Linna Fang, Louis Boafo Kwantwi, Guifang He, Wenwu Luo, Lijie Yang, Yuhang Huang, Shiyuan Yin, Yongping Cai, Wei Ma, Heqin Zhan, Zhuting Tong, Li Zhang, Chaozhao Liang, Yu Yin

Med Oncol. 2021; 38(10): 127. Published online 2021 Sep 14. doi: 10.1007/s12032-021-01575-x

PMCID:: PMC8440287

Abstract Article PDF–1.9M

Select item 829252710.

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu

Nat Commun. 2021; 12: 4413. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24703-7

PMCID:: PMC8292527

Abstract Article PDF–6.5M

Select item 824045111.

Targeted silencing of TEM8 suppresses non-small cell lung cancer tumor growth via the ERK/Bcl-2 signaling pathway

Quan Gong, Jing Deng, Lijuan Zhang, Chunyan Zhou, Chaojiang Fu, Xicai Wang, Li Zhuang

Mol Med Rep. 2021 Aug; 24(2): 595. Published online 2021 Jun 22. doi: 10.3892/mmr.2021.12234

PMCID:: PMC8240451

Abstract Article PDF–771K

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814520813.

N-Linked Glycosylation on Anthrax Toxin Receptor 1 Is Essential for Seneca Valley Virus Infection

Nadishka Jayawardena, Linde A. Miles, Laura N. Burga, Charles Rudin, Matthias Wolf, John T. Poirier, Mihnea Bostina

Viruses. 2021 May; 13(5): 769. Published online 2021 Apr 28. doi: 10.3390/v13050769

PMCID:: PMC8145208

Abstract Article PDF–7.3M

Select item 715683314.

Anthrax toxin receptor 1/tumor endothelial marker 8 promotes gastric cancer progression through activation of the PI3K/AKT/mTOR signaling pathway

Chen Cai, Wei Dang, Shilei Liu, Ling Huang, Yang Li, Guoqiang Li, Siyuan Yan, Chengkai Jiang, Xiaoling Song, Yunping Hu, Jun Gu

Cancer Sci. 2020 Apr; 111(4): 1132–1145. Published online 2020 Feb 19. doi: 10.1111/cas.14326

PMCID:: PMC7156833

Abstract Article PDF–2.9M

Select item 677813715.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 671373616.

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins

Sascha E. Dho, Nancy Silva-Gagliardi, Fabio Morgese, Etienne Coyaud, Emily Lamoureux, Donna M. Berry, Brian Raught, C. Jane McGlade

Sci Rep. 2019; 9: 12471. Published online 2019 Aug 28. doi: 10.1038/s41598-019-48902-x

PMCID:: PMC6713736

Abstract Article PDF–5.6M

Select item 629825417.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 624325318.

Structural basis for anthrax toxin receptor 1 recognition by Seneca Valley Virus

Nadishka Jayawardena, Laura N. Burga, Richard A. Easingwood, Yoshimasa Takizawa, Matthias Wolf, Mihnea Bostina

Proc Natl Acad Sci U S A. 2018 Nov 13; 115(46): E10934–E10940. Published online 2018 Oct 31. doi: 10.1073/pnas.1810664115

PMCID:: PMC6243253

Abstract Article PDF–2.3M

Select item 615105019.

TEM8 functions as a receptor for uPA and mediates uPA-stimulated EGFR phosphorylation

Lian-Cheng Zhang, Yong Shao, Li-Hua Gao, Jin Liu, Yong-Yi Xi, Yin Xu, Chutse Wu, Wei Chen, Hui-Peng Chen, You-Liang Wang, Hai-Feng Duan, Xian-Wen Hu

Cell Commun Signal. 2018; 16: 62. Published online 2018 Sep 21. doi: 10.1186/s12964-018-0272-8

PMCID:: PMC6151050

Abstract Article PDF–2.2M

Select item 593305320.

A Biallelic ANTXR1 Variant Expands the Anthrax Toxin Receptor Associated Phenotype to Tooth Agenesis

Nuriye Dinckan, Renqian Du, Zeynep Coban Akdemir, Yavuz Bayram, Shalini Jhiangiani, Harsha Doddapaneni, Jianhong Hu, Donna M. Muzny, Yeliz Guven, Oya Aktoren, Hulya Kayserili, Eric Boerwinkle, Richard A. Gibbs, Jennifer E. Posey, James R. Lupski, Zehra Oya Uyguner, Ariadne Letra

Am J Med Genet A. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Am J Med Genet A. 2018 Apr; 176(4): 1015–1022. Published online 2018 Feb 13. doi: 10.1002/ajmg.a.38625

PMCID:: PMC5933053

Abstract Article PDF–714K

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