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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 101015002.

The active zone protein Clarinet regulates synaptic sorting of ATG-9 and presynaptic autophagy

Zhao Xuan, Sisi Yang, Benjamin Clark, Sarah E. Hill, Laura Manning, Daniel A. Colón-Ramos

PLoS Biol. 2023 Apr; 21(4): e3002030. Published online 2023 Apr 13. doi: 10.1371/journal.pbio.3002030

PMCID:: PMC10101500

Abstract Article PDF–4.4M

Select item 91299223.

SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion

Xianghong Wang, Xinxin Li, Junkai Wang, Jiabin Wang, Can Hu, Jia Zeng, Anbing Shi, Long Lin

J Cell Biol. 2022 Jul 4; 221(7): e202111125. Published online 2022 May 23. doi: 10.1083/jcb.202111125

PMCID:: PMC9129922

Abstract Article PDF–8.5M

Select item 83311834.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 79951765.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 68273686.

Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules

Elisabeth A. Marnik, J. Heath Fuqua, Catherine S. Sharp, Jesse D. Rochester, Emily L. Xu, Sarah E. Holbrook, Dustin L. Updike

Genetics. 2019 Nov; 213(3): 923–939. Published online 2019 Sep 10. doi: 10.1534/genetics.119.302670

PMCID:: PMC6827368

Abstract Article PDF–4.0M

Select item 68261457.

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun

Aging Cell. 2019 Dec; 18(6): e13012. Published online 2019 Aug 9. doi: 10.1111/acel.13012

PMCID:: PMC6826145

Abstract Article PDF–3.0M

Select item 67398738.

A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex

Edward A Partlow, Richard W Baker, Gwendolyn M Beacham, Joshua S Chappie, Andres E Leschziner, Gunther Hollopeter

eLife. 2019; 8: e50003. Published online 2019 Aug 29. doi: 10.7554/eLife.50003

PMCID:: PMC6739873

Abstract Article PDF–3.1M

Select item 62165909.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 578520910.

NECAPs are negative regulators of the AP2 clathrin adaptor complex

Gwendolyn M Beacham, Edward A Partlow, Jeffrey J Lange, Gunther Hollopeter

eLife. 2018; 7: e32242. Published online 2018 Jan 18. doi: 10.7554/eLife.32242

PMCID:: PMC5785209

Abstract Article PDF–3.1M

Select item 485894511.

In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics

Jia-Xuan Chen, Patricia G. Cipriani, Desirea Mecenas, Jolanta Polanowska, Fabio Piano, Kristin C. Gunsalus, Matthias Selbach

Mol Cell Proteomics. 2016 May; 15(5): 1642–1657. Published online 2016 Feb 24. doi: 10.1074/mcp.M115.053975

PMCID:: PMC4858945

Abstract Article PDF–3.1M

Select item 443683312.

The AP2 clathrin adaptor protein complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans

Steven D. Garafalo, Eric S. Luth, Benjamin J. Moss, Michael I. Monteiro, Emily Malkin, Peter Juo

Mol Biol Cell. 2015 May 15; 26(10): 1887–1900. doi: 10.1091/mbc.E14-06-1048

PMCID:: PMC4436833

Abstract Article PDF–715K

Select item 421553613.

The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex

Gunther Hollopeter, Jeffrey J Lange, Ying Zhang, Thien N Vu, Mingyu Gu, Michael Ailion, Eric J Lambie, Brian D Slaughter, Jay R Unruh, Laurence Florens, Erik M Jorgensen

eLife. 2014; 3: e03648. Published online 2014 Oct 10. doi: 10.7554/eLife.03648

PMCID:: PMC4215536

Abstract Article PDF–5.0M

Select item 371811214.

Regulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membrane

Jonathan R. Mayers, Lei Wang, Jhuma Pramanik, Adam Johnson, Ali Sarkeshik, Yueju Wang, Witchuda Saengsawang, John R. Yates, III, Anjon Audhya

Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29): 11857–11862. Published online 2013 Jul 1. doi: 10.1073/pnas.1302918110

PMCID:: PMC3718112

Abstract Article PDF–907K

Select item 365614415.

Clathrin and AP2 Are Required for Phagocytic Receptor-Mediated Apoptotic Cell Clearance in Caenorhabditis elegans

Didi Chen, Youli Jian, Xuezhao Liu, Yuanya Zhang, Jingjing Liang, Xiaying Qi, Hongwei Du, Wei Zou, Lianwan Chen, Yongping Chai, Guangshuo Ou, Long Miao, Yingchun Wang, Chonglin Yang

PLoS Genet. 2013 May; 9(5): e1003517. Published online 2013 May 16. doi: 10.1371/journal.pgen.1003517