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Select item 112614481.

Mutations in tyrosyl-DNA phosphodiesterase 2 suppress top-2 induced chromosome segregation defects during Caenorhabditis elegans spermatogenesis

Ji Kent Kwah, Nirajan Bhandari, Christine Rourke, Gabriella Gassaway, Aimee Jaramillo-Lambert

J Biol Chem. 2024 Jul; 300(7): 107446. Published online 2024 Jun 4. doi: 10.1016/j.jbc.2024.107446

PMCID:: PMC11261448

Abstract Article PDF–3.1M

Select item 108029522.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 104832803.

Transcriptional repression during spermatogenesis in C. elegans requires TOP-2, condensin II, and the MET-2 H3K9 methyltransferase.

Emilie Chien, W. Matthew Michael

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000933. Published online 2023 Aug 23. doi: 10.17912/micropub.biology.000933

PMCID:: PMC10483280

Abstract Article PDF–1.9M

Select item 103958374.

Characterization of factors that underlie transcriptional silencing in C. elegans oocytes

Mezmur D. Belew, Emilie Chien, W. Matthew Michael

PLoS Genet. 2023 Jul; 19(7): e1010831. Published online 2023 Jul 21. doi: 10.1371/journal.pgen.1010831

PMCID:: PMC10395837

Abstract Article PDF–2.7M

Select item 98376125.

Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans

Ana Karina Morao, Jun Kim, Daniel Obaji, Siyu Sun, Sevinc Ercan

Mol Cell. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Mol Cell. 2022 Nov 17; 82(22): 4202–4217.e5. Published online 2022 Oct 26. doi: 10.1016/j.molcel.2022.10.002

PMCID:: PMC9837612

Abstract Article PDF–3.0M

Select item 95260626.

TOP-2 is differentially required for the proper maintenance of the cohesin subunit REC-8 on meiotic chromosomes in Caenorhabditis elegans spermatogenesis and oogenesis

Christine Rourke, Aimee Jaramillo-Lambert

Genetics. 2022 Oct; 222(2): iyac120. Published online 2022 Aug 11. doi: 10.1093/genetics/iyac120

PMCID:: PMC9526062

Abstract Article PDF–1.5M

Select item 94378487.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 84467938.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 83311839.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 821057410.

A global chromatin compaction pathway that represses germline gene expression during starvation

Mezmur D. Belew, Emilie Chien, Matthew Wong, W. Matthew Michael

J Cell Biol. 2021 Sep 6; 220(9): e202009197. Published online 2021 Jun 15. doi: 10.1083/jcb.202009197

PMCID:: PMC8210574

Abstract Article PDF–4.2M

Select item 817051011.

Endogenous localization of TOP-2 in C. elegans using a C-terminal GFP-tag

Christine K. Rourke, Darline Murat, Tyler J. Hansen, Aimee Jaramillo-Lambert

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000402. Published online 2021 May 28. doi: 10.17912/micropub.biology.000402

PMCID:: PMC8170510

Abstract Article PDF–33M

Select item 799517612.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 722730513.

GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability

Gregoriy A. Dokshin, Gregory M. Davis, Ashley D. Sawle, Matthew D. Eldridge, Peter K. Nicholls, Taylin E. Gourley, Katherine A. Romer, Luke W. Molesworth, Hannah R. Tatnell, Ahmet R. Ozturk, Dirk G. de Rooij, Gregory J. Hannon, David C. Page, Craig C. Mello, Michelle A. Carmell

Dev Cell. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Dev Cell. 2020 Jan 6; 52(1): 53–68.e6. Published online 2019 Dec 12. doi: 10.1016/j.devcel.2019.11.006

PMCID:: PMC7227305

Abstract Article PDF–1.3M

Select item 714408314.

Identification of Suppressors of top-2 Embryonic Lethality in Caenorhabditis elegans

Nirajan Bhandari, Christine Rourke, Thomas Wilmoth, Alekya Bheemreddy, David Schulman, Dina Collins, Harold E. Smith, Andy Golden, Aimee Jaramillo-Lambert

G3 (Bethesda) 2020 Apr; 10(4): 1183–1191. Published online 2020 Feb 21. doi: 10.1534/g3.119.400927

PMCID:: PMC7144083

Abstract Article PDF–1.5M

Select item 663896615.

The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline

Simon Yuan Wang, Hui Mao, Hiroki Shibuya, Satoru Uzawa, Zach Klapholz O’Brown, Sage Wesenberg, Nara Shin, Takamune T. Saito, Jinmin Gao, Barbara J. Meyer, Monica P. Colaiácovo, Eric Lieberman Greer

PLoS Genet. 2019 Jul; 15(7): e1008252. Published online 2019 Jul 8. doi: 10.1371/journal.pgen.1008252

PMCID:: PMC6638966

Abstract Article PDF–2.6M

Select item 621659016.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 613707617.

FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells

Ena Kolundzic, Andreas Ofenbauer, Selman I. Bulut, Bora Uyar, Gülkiz Baytek, Anne Sommermeier, Stefanie Seelk, Mei He, Antje Hirsekorn, Dubravka Vucicevic, Altuna Akalin, Sebastian Diecke, Scott A. Lacadie, Baris Tursun

Dev Cell. 2018 Sep 10; 46(5): 611–626.e12. doi: 10.1016/j.devcel.2018.07.006